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Protein Overview: SRP102

General Information:
Name(s) found: SRP102 / YKL154W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 244 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    signal recognition particle receptor complex [TASLink to PubMed article]
    Biological Process: SRP-dependent cotranslational protein targeting to membrane [ICLink to PubMed article][TASLink to PubMed article]
    protein targeting to ER [IMPLink to PubMed article]
    Molecular Function: GTP binding [IPILink to PubMed article]
    GTPase activity [ISSLink to PubMed article]
    signal recognition particle binding [IMPLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSNTLIIAC LLVIGTTIAL IAVQKASSKT GIKQKSYQPS IIIAGPQNSG KTSLLTLLTT  60
   61 DSVRPTVVSQ EPLSAADYDG SGVTLVDFPG HVKLRYKLSD YLKTRAKFVK GLIFMVDSTV 120
  121 DPKKLTTTAE FLVDILSITE SSCENGIDIL IACNKSELFT ARPPSKIKDA LESEIQKVIE 180
  181 RRKKSLNEVE RKINEEDYAE NTLDVLQSTD GFKFANLEAS VVAFEGSINK RKISQWREWI 240
  241 DEKL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) SRP101 SRP102
    View Details (MIPS) Mewes HW, et al. (2004) SRP101 SRP102
    View Details Gavin AC, et al. (2006) SRP101 SRP102
    View Details Gavin AC, et al. (2002) SRP101 SRP102
    View Details Qiu et al. (2008) MLP1 MLP2 SBH1 SBH2 SEC11 SEC59 SEC62 SEC66 SRP101 SRP102 SSH1 SSS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SRP102 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 92.035458 ADP-ribosylation factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • signal recognition particle binding
    		•  5.12760449152779 bayes_pls_golite062009
  • ribonucleoprotein binding
    		•  3.19511216911452 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • binding
    		•  1.77927104644254 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.640772201693186 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.63468044350616 bayes_pls_golite062009
  • GTP binding
    		•  0.621689261700018 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle