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Protein Overview: SBH1

General Information:
Name(s) found: SBH1 / YER087C-B [SGD]
Description(s) found:
Found 28 descriptions.
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  • Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; homologous to Sbh2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 82 amino acids

    Gene Ontology:
    Cellular Component: Sec61 translocon complex [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: SRP-dependent cotranslational protein targeting to membrane, translocation [TASLink to PubMed article]
    cotranslational protein targeting to membrane [IDALink to PubMed article][TASLink to PubMed article]
    posttranslational protein targeting to membrane, translocation [TASLink to PubMed article]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IDALink to PubMed article]
    protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPTPPGGQ RTLQKRKQGS SQKVAASAPK KNTNSNNSIL KIYSDEATGL RVDPLVVLFL  60
   61 AVGFIFSVVA LHVISKVAGK LF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) SBH1 SEC61 SSS1
    View Details Qiu et al. (2008) ERI1 SBH1 SBH2 SEC12 SEC20 SEC61 SEC62 SEC63 SEC66 SEC72 SPC2 SRP101 SRP102 SSH1 SSS1 YOS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SBH1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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