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Protein Overview: ERI1

General Information:
Name(s) found: ERI1 / YPL096C-A [SGD]
Description(s) found:
Found 20 descriptions.
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  • Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2p at the ER; component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 68 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex [IPILink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article]
    Ras protein signal transduction [IMPLink to PubMed article]
    Molecular Function: GTPase inhibitor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPRDQGFLV LGFTYSVLLI SLATFYWLRN NDSFLHYWCV LLLCPATLWL WALIAWCDSE  60
   61 MFASSKDE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERI1 GAA1 GAB1 GPI1 GPI11 GPI12 GPI14 GPI15 GPI16 GPI17 GPI19 GPI2 SBH1 SHR5 SPT14 SUR4 YLL017W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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