Protein Overview: GPI16

General Information:
Name(s) found:	GPI16 / YHR188C [SGD]
Description(s) found: Found 18 descriptions. SHOW ALL	Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog [SGD]
Organism:	Saccharomyces cerevisiae
Length:	610 amino acids
Gene Ontology:
Cellular Component:	GPI-anchor transamidase complex [IPI]
Biological Process:	attachment of GPI anchor to protein [IMP]
Molecular Function:	GPI-anchor transamidase activity [IMP][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILTLAYFML GTLLLGVFAE DTVSQIGIND SLWYPYDEAL VLKPLPNNDL LLSFAFQLQS  60
   61 EPFDPAVSSM SYDAYEHYTT FPRAIPPLLE STATRQFHLR FTRGFWDALS WGQLPHAGKE 120
  121 AGASGVELWS QVQAMDQEQA FHNWKKLSNS LSGLFCSSLN FIDESRTTFP RRSYASDIGA 180
  181 PLFNSTEKLY LMRASLPNEP ICTENLTPFI KLLPTRGKSG LTSLLDGHKL FDSLWNSISL 240
  241 DIATICSEDE DALCHYEMDA RIEMVTHVPS ALARGERPIP KPLDGNTLRC DTDKPFDSYQ 300
  301 CFPLPEPSQT HFKLSQLFAR PINNGNLFAN RPTRICAEVD RSTWTAFLSV DDTIFSTHDN 360
  361 CFDLSNDQNE GGSGYDFILE STDTTKVTPI VPVPIHVSRS LTGNGQDRGG MRIVFHNDND 420
  421 TPVKLIYFES LPWFMRVYLS SLQITSTTSP QLQENDIILD KYYLQAADRK RPGHLEFTML 480
  481 IPANTDIVMT YQFDKALLQF AEYPPDANHG FEIDAAVITV LSLESSSSLY EMRTSTLLLS 540
  541 LSTPDFSMPY NVIILTSTIM GLIFGMLYNL MVKRMVTVEE ADKITLQSGL KYKLLKLKEK 600
  601 FLGKKKTKTD

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		ARF1 ARF2 GPI16
View Details	Qiu et al. (2008)		ERI1 GAA1 GAB1 GPI16 GPI17 GPI19 GPI8

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	GPI16	YJR015W	2	Uetz P, et al. (2000)

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..114]	deduced	N/A	Confident ab initio structure predictions are available.
2	View Details	[115..267]	MSA	1.008969	View MSA. No confident structure predictions are available.
3	View Details	[268..610]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2