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Protein Overview: GAB1

General Information:
Name(s) found: GAB1 / YLR459W [SGD]
Description(s) found:
Found 27 descriptions.
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  • GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 394 amino acids

    Gene Ontology:
    Cellular Component: GPI-anchor transamidase complex [IMPLink to PubMed article][IPILink to PubMed article]
    Biological Process: attachment of GPI anchor to protein [ISSLink to PubMed article]
    Molecular Function: GPI-anchor transamidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSTALKVAL GCIAIRLAVN SLFPSLQQQL DQSVEFSTPV TSFRSLQEGI YLLRNNIQVY  60
   61 NHGVVHHPPI LIFFLSLFNS DRLISLIYAL IDGLIAYQLT EVTKAFKNLK LKVWLPGLLY 120
  121 AVNPLTLLSC ISRSSIIFTN FAISSSLYCI LAEGNVLLSS VMISISGYLS VYPILLLIPL 180
  181 LGMLKSWRQR ILSAIVSILS LLILLLFSYS ILGSQSWSFL TQVYGSIITF EKVFPNLGLW 240
  241 WYFFIEMFDT FIPFFKAVFN IFIAVFITPF TLRYHKQPFY AFILCIGWIV LTKPYPSLGD 300
  301 AGFFFSFLPF FTPLFGYLRY PIISALLFLH AIVLAPIFYH LWVVLGSGNS NFFYAISLVY 360
  361 ALAIASILVD LNWAMLRIEY DNGIPNFKLK VTQI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERI1 GAA1 GAB1 GPI11 GPI16 GPI17 GPI8

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] MSA 1.017982 View MSA. No confident structure predictions are available.
    2 View Details [128..188] deduced N/A No confident structure predictions are available.
    3 View Details [189..319] MSA 2.018977 View MSA. No confident structure predictions are available.
    4 View Details [320..394] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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