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Protein Overview: GPI19

General Information:
Name(s) found: GPI19 / YDR437W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 140 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex [IPILink to PubMed article][ISSLink to PubMed article]
    integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed articleLink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [ICLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: UDP-glycosyltransferase activity [ICLink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTKEYYWFS QYMIITSTLV LTIIWSILPS SLGEAAPKQF INTLLDIFPQ RRWIITLESI  60
   61 MLMGMLCTYI GLLMYNEDTL TPPLDSLSTV TDAGGQLVIE DDPDVFVKKW AFKETSGIYD 120
  121 LSLMDACQLL YLYDNDHTST

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERI1 GPI1 GPI14 GPI15 GPI16 GPI19 SPT14

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen GPI19 GET3 2 Hazbun TR, et al. (2003)
    View Screen GPI19 BAP3 2 Hazbun TR, et al. (2003)
    View Screen GPI19 YJR015W 2 Hazbun TR, et al. (2003)
    View Screen GPI19 GET3 2 Hazbun TR, et al. (2003)
    View Screen GPI19 YJR015W 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GPI19 and TRX3 Hazbun TR, et al. (2003)
    View Data GPI19 and SPC42 Hazbun TR, et al. (2003)
    View Data GPI19 and SPC42 Unpublished Data
    View Data GPI19 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] Pcons 1.88 Streptococcal pyrogenic exotoxin A1


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle