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Protein Overview: GPI2

General Information:
Name(s) found: GPI2 / YPL076W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex [IPILink to PubMed article][TASLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: UDP-glycosyltransferase activity [ICLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRSPWKRLL WLKQEYPDNY TDPSFIELRA RQKAESNQKS DRKLSEAARA QIRLDFISFY  60
   61 QTILNTSFIY ITFTYIYYYG FDPIPPTIFL SFITLIISRT KVDPLLSSFM DVKSSLIITF 120
  121 AMLTLSPVLK SLSKTTASDS IWTLSFWLTL WYIFVISSTK SKDKPSNLST NILVALVAVL 180
  181 SSRLSTTIDV FCFLLICIQL NIILPTYLSV TNKVVPIISN IIVYSFLNVA LGWIYMLLIF 240
  241 FASVFYITVL PKWFIYWKIN YHKRDNDLLS TWDARTPILD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERI1 GPI1 GPI15 GPI2 SPT14

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GPI2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] MSA 1.013997 View MSA. No confident structure predictions are available.
    2 View Details [185..280] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle