YRC Public Data Repository - Protein Structure Prediction

Protein:	SRP102
Organism:	Saccharomyces cerevisiae
Length:	244 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SRP102.

Description	E-value	Query Range	Subject Range
ARF1_SOLTU - ADP-ribosylation factor 1 OS=Solanum tuberosum PE=2 SV=2	8.0E-62	[26..218]	[5..185]
gi\|4056469, gi\|2... - gi\|4056469\|gb\|AAC98042.1\| Strong similarity to gb\|M95166 ADP-ribosylation factor from Arabidopsis th...	3.0E-61	[24..205]	[3..174]
ARF1_XENLA - ADP-ribosylation factor 1 OS=Xenopus laevis GN=arf1 PE=2 SV=2	4.0E-61	[24..207]	[3..176]
gi\|6815060, gi\|3... - gi\|7242921\|dbj\|BAA92519.1\| putative ADP-ribosylation factor [Oryza sativa Japonica Group], gi\|681506...	5.0E-61	[26..205]	[5..174]
ARF1_SALBA - ADP-ribosylation factor 1 OS=Salix bakko GN=ARF1 PE=2 SV=3 gi\|29124981 - gi\|29124981\|gb\|AAO63780.1\| ADP-ribosylation factor 2 [Populus tremuloides] gi\|224108844, gi... - gi\|224108844\|ref\|XP_002314987.1\| predicted protein [Populus trichocarpa], gi\|222864027\|gb\|EEF01158.1...	5.0E-61	[24..205]	[3..174]
ARF_VIGUN - ADP-ribosylation factor OS=Vigna unguiculata GN=ARF PE=2 SV=3	6.0E-61	[24..205]	[3..174]
gi\|4324967 - gi\|4324967\|gb\|AAD17207.1\| ADP-ribosylation factor [Glycine max]	8.0E-61	[26..205]	[2..171]
gi\|125552797 - gi\|125552797\|gb\|EAY98506.1\| hypothetical protein OsI_20417 [Oryza sativa Indica Group] gi\|242090913, gi... - gi\|242090913\|ref\|XP_002441289.1\| hypothetical protein SORBIDRAFT_09g023880 [Sorghum bicolor], gi\|241... gi\|23304413 - gi\|23304413\|emb\|CAD48129.2\| ADP-ribosylation factor 1-like protein [Hordeum vulgare subsp. vulgare] ARF2_ORYSJ - ADP-ribosylation factor 2 OS=Oryza sativa subsp. japonica GN=ARF PE=2 SV=2 gi\|357125554\|ref... - PREDICTED: ADP-ribosylation factor 2-like [Brachypodium distachyon] gi\|13646976 - gi\|13646976\|dbj\|BAB41081.1\| ADP-ribosylation factor [Triticum aestivum] ARF2_ORYSA - ADP-ribosylation factor 2 - Oryza sativa (Rice)	8.0E-61	[26..205]	[5..174]
tr\|G1TXQ6\|G1TXQ6... - pep:novel scaffold:oryCun2:GL019112:79657:80606:-1 gene:ENSOCUG00000023645 transcript:ENSOCUT0000002... ARF1_MACFA - ADP-ribosylation factor 1 OS=Macaca fascicularis GN=ARF1 PE=2 SV=3 ENSCJAT00000032503 - null gi\|168277944, gi... - gi\|61362573\|gb\|AAX42245.1\| ADP-ribosylation factor 1 [synthetic construct], gi\|61362566\|gb\|AAX42244.... gi\|542165806\|ref... - PREDICTED: ADP-ribosylation factor 1 [Zonotrichia albicollis] ARF1 - ADP-ribosylation factor 1 gi\|149759398 - gi\|149759398\|ref\|XP_001494680.1\| PREDICTED: similar to ADP-ribosylation factor 1 isoform 1 [Equus ca... gi\|242247455, gi... - gi\|242247455\|ref\|NP_001156016.1\| ADP-ribosylation factor 1 [Ovis aries], gi\|238799786\|gb\|ACR55765.1\|... ARF1_MOUSE - ADP-ribosylation factor 1 OS=Mus musculus GN=Arf1 PE=1 SV=2 gi\|50732153 - ref\|XP_418504.1\| PREDICTED: similar to ADP-ribosylation factor 1 [Gallus gallus] ARF1_RAT - ADP-ribosylation factor 1 OS=Rattus norvegicus GN=Arf1 PE=1 SV=2 ARF1_BOVIN - ADP-ribosylation factor 1 OS=Bos taurus GN=ARF1 PE=1 SV=2 gi\|224044540 - gi\|224044540\|ref\|XP_002194825.1\| PREDICTED: ADP-ribosylation factor 1 [Taeniopygia guttata] gi\|212725657, gi... - gi\|238018148\|ref\|NP_001153899.1\| ADP-ribosylation factor 1 [Sus scrofa], gi\|237638742\|gb\|ACR07973.1\|... CCDS1565.1_1 - null gi\|114573018, gi... - gi\|114573032\|ref\|XP_001145210.1\| PREDICTED: similar to ADP-ribosylation factor isoform 14 [Pan trogl... ENSMMUG000000027... - null, null gi\|120577632 - gi\|120577632\|gb\|AAI30157.1\| Arf-1 protein [Xenopus laevis]	8.0E-61	[24..207]	[3..176]

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Predicted Domain #1

Region A:
Residues: [1-244]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSNTLIIAC LLVIGTTIAL IAVQKASSKT GIKQKSYQPS IIIAGPQNSG KTSLLTLLTT  60
   61 DSVRPTVVSQ EPLSAADYDG SGVTLVDFPG HVKLRYKLSD YLKTRAKFVK GLIFMVDSTV 120
  121 DPKKLTTTAE FLVDILSITE SSCENGIDIL IACNKSELFT ARPPSKIKDA LESEIQKVIE 180
  181 RRKKSLNEVE RKINEEDYAE NTLDVLQSTD GFKFANLEAS VVAFEGSINK RKISQWREWI 240
  241 DEKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	92.035458
Match:	1fzqA_
Description:	ADP-ribosylation factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
signal recognition particle binding	5.12760449152779	bayes_pls_golite062009
ribonucleoprotein binding	3.19511216911452	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
binding	1.77927104644254	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
motor activity	0.87979065815418	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
GTPase activity	0.437665353870877	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.213018989352421	bayes_pls_golite062009
protein binding	0.193768631623192	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0775601177068852	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: