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Protein Overview: GYP6

General Information:
Name(s) found: GYP6 / YJL044C [SGD]
Description(s) found:
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  • gi|6322417|ref|NP_012491.1| GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport; Gyp6p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1170142|sp|P32806.2|GYP6_YEAST RecName: Full=GTPase-activating protein GYP6; AltName: Full=GAP for YPT6 [NCBI NR]
  • pir||S56816 GTPase-activating protein GYP6 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1008173|emb|CAA89335.1| GYP6 [Saccharomyces cerevisiae] [NCBI NR]
  • GTPase-activating protein GYP6 OS=Saccharomyces cerevisiae GN=GYP6 PE=1 SV=2 [Swiss-Prot]
  • GYP6 GTPase-activating protein [mips]
  • GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport [SGD]
  • GYP6, Chr X from 357996-359372, reverse complement [yeast_orfs2]
  • Chr X from 357996-359372, reverse complement [yeastorf3.fasta]
  • Chr X from 359372-357996, reverse complement [yeastorf5.fasta]
  • (P32806) GTPase-activating protein GYP6 (GAP for YPT6) [4932.FASTACCERV.txt]
  • GYP6 SGDID:S0003580, Chr X from 359592-358216, reverse complement, Verified ORF [yeastflysequest.fasta]
  • GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport [Saccharomyces cerevisiae]gi|1008173|emb|CAA89335.1| GYP6 [Saccharomyces cerevisiae]gi|1077143|pir||S56816 GTPase-activating protein G [nrdb_11152004_Chlamydomonas]
  • GYP6 SGDID:S000003580, Chr X from 359592-358216, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • GYP6 SGDID:S000003580, Chr X from 359671-358295, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" [yeast-contam.fasta]
  • GYP6 SGDID:S000003580, Chr X from 359670-358294, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" [yeast-200209-contam.fasta]
  • GYP6 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • GTPase-activating protein GYP6 (GAP for YPT6) [nr-271106-contam.fasta]
  • GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport; Gyp6p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • GTPase-activating protein GYP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GYP6 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • GYP6 SGDID:S000003580, Chr X from 359676-358300, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" [yeast-030211-contam.fasta]
  • GYP6 SGDID:S000003580, Chr X from 359676-358300, Genome Release 64-2-1, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for yeast Rab family member Ypt6p; involved in vesicle mediated protein transport" [20141208_orf_trans.fasta]
  • YJL044C SGDID:S000003580, Chr X from 359676-358300, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: endosome [IDALink to PubMed article]
    clathrin-coated vesicle [IDALink to PubMed article]
    Biological Process: intracellular protein transport [ISSLink to PubMed article]
    Molecular Function: GTPase activator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDVLQWAID HYETRDQLVQ KGIWKGELYH DSIFKENSRG WLWKALLLCD ENNNCLLTDN  60
   61 FKGLDLNQFG LVPVPMLADG DNYDENHNAN VPKRVLHSNV SSSVGIRRLT PVEAVEKHPL 120
  121 SDDNDKTKGS LSKGSDEKPL TLRETLEIID LDLSRIMLDD IFQEPKVHAQ MRQLLYNYLL 180
  181 IHQSEHLQYK QGFHEILSVI YLQLYHGTDL DNTDLQNVLI IFNKLMNQIE PIFYNEENLI 240
  241 NWDKRVFTKI FRICLPDLFS KVFYQPPKTG SGKKKNVDHL IHSNLIWLIR WTRLLFLREL 300
  301 PLKYVLIVWD HVLTFNYPLD IFIACTIITL LLSIYDELHE LVSQGDYEHT NNNDEFVELI 360
  361 LHFKKIFEKE DASKDDEKFL DLCKVTGNLC ELWYGKNYDD MRLICDTFIN AKFGIKTSDV 420
  421 LSMETAKLTI DPNRQSLENK LRERVRQTIL KNKKKISQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BET3 GYP6 TRS20
    View Details Ho Y, et al. (2002) GYP6 TRS120 TRS130
    View Details Qiu et al. (2008) GYP6 TRS23 TRS31

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC4 GYP6 1 Unpublished Fields Lab Data
    View Screen GYP6 CPR6 1 Unpublished Fields Lab Data
    View Screen GYP6 FUN19 1 Unpublished Fields Lab Data
    View Screen GYP6 PSY3 1 Unpublished Fields Lab Data
    View Screen GYP6 YBR138C 1 Unpublished Fields Lab Data
    View Screen GYP6 CSM3 1 Unpublished Fields Lab Data
    View Screen GYP6 YBR284W 1 Unpublished Fields Lab Data
    View Screen GYP6 SPT21 1 Unpublished Fields Lab Data
    View Screen GYP6 USO1 1 Unpublished Fields Lab Data
    View Screen GYP6 RNT1 1 Unpublished Fields Lab Data
    View Screen GYP6 TIM22 1 Unpublished Fields Lab Data
    View Screen GYP6 MET4 1 Unpublished Fields Lab Data
    View Screen GYP6 SNF11 1 Unpublished Fields Lab Data
    View Screen GYP6 LSM7 1 Unpublished Fields Lab Data
    View Screen GYP6 MCM21 1 Unpublished Fields Lab Data
    View Screen GYP6 UAF30 1 Unpublished Fields Lab Data
    View Screen GYP6 SPT3 1 Unpublished Fields Lab Data
    View Screen GYP6 YPR172W 1 Unpublished Fields Lab Data
    View Screen GYP6 BIG1 1 Unpublished Fields Lab Data
    View Screen GYP6 YPR195C 1 Unpublished Fields Lab Data
    View Screen GYP6 ARP1 1 Unpublished Fields Lab Data
    View Screen GYP6 SVP26 1 Unpublished Fields Lab Data
    View Screen GYP6 AIM46 1 Unpublished Fields Lab Data
    View Screen GYP6 GVP36 1 Unpublished Fields Lab Data
    View Screen GYP6 TOA2 1 Unpublished Fields Lab Data
    View Screen GBP2 GYP6 1 Unpublished Fields Lab Data
    View Screen GYP6 ACF2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GYP6 Huh WK, et al. (2003)
    View Data GYP6 and CHC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] deduced N/A No confident structure predictions are available.
    2 View Details [83..238]
    [307..348]    		 PSI-BLAST 33.39794 Ypt/Rab-GAP domain of gyp1p
    3 View Details [239..306] PSI-BLAST 33.39794 Ypt/Rab-GAP domain of gyp1p
    4 View Details [349..458] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle