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Protein Overview: BIG1

General Information:
Name(s) found: BIG1 / YHR101C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 335 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: fungal-type cell wall biogenesis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTVLKYLLL IMCGSFCASE ELQNQTNVPA IFFSYKLTPG ILKYQEDYDR AVTLPRDTFI  60
   61 EAAEKFLGVC NADTYVFINQ PGLRKLDFLE FETEFVSLQR YIRRSSTAIK FEKVDLLPQD 120
  121 LYYDLAEFVK EYCNVDQVLN LRGNNTEDFQ PFIDSEKRVI IIEYPKLPED TNERKEAFRH 180
  181 YDKYLRTILA QIPSPEQNVI YTSLNPGTTL AHESIIPIQI FPDIFDIKSR VGEVEQNNRV 240
  241 LDVPRLSFND YTPRFSEPPS EYVSIFDSQL IENNRGLLQL IFTILVGYIL IQFFFTKKTI 300
  301 VDEKITNKKD NVKQTSPQLL KKVQEIQKKP SQQVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BIG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..335] deduced N/A No confident structure predictions are available.
    2 View Details [204..335] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle