YRC Public Data Repository - Protein Structure Prediction

Protein:	BIG1
Organism:	Saccharomyces cerevisiae
Length:	335 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIG1.

Description	E-value	Query Range	Subject Range
BIG1_YEAST - Protein BIG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BIG1 PE=1 SV=1 BIG1 - Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall bet... gi\|190405880 - gi\|190405880\|gb\|EDV09147.1\| hypothetical protein SCRG_04814 [Saccharomyces cerevisiae RM11-1a]	0.0	[1..335]	[1..335]

Back

Predicted Domain #1

Region A:
Residues: [1-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTVLKYLLL IMCGSFCASE ELQNQTNVPA IFFSYKLTPG ILKYQEDYDR AVTLPRDTFI  60
   61 EAAEKFLGVC NADTYVFINQ PGLRKLDFLE FETEFVSLQR YIRRSSTAIK FEKVDLLPQD 120
  121 LYYDLAEFVK EYCNVDQVLN LRGNNTEDFQ PFIDSEKRVI IIEYPKLPED TNERKEAFRH 180
  181 YDKYLRTILA QIPSPEQNVI YTSLNPGTTL AHESIIPIQI FPDIFDIKSR VGEVEQNNRV 240
  241 LDVPRLSFND YTPRFSEPPS EYVSIFDSQL IENNRGLLQL IFTILVGYIL IQFFFTKKTI 300
  301 VDEKITNKKD NVKQTSPQLL KKVQEIQKKP SQQVS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [204-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNPGTTLAHE SIIPIQIFPD IFDIKSRVGE VEQNNRVLDV PRLSFNDYTP RFSEPPSEYV  60
   61 SIFDSQLIEN NRGLLQLIFT ILVGYILIQF FFTKKTIVDE KITNKKDNVK QTSPQLLKKV 120
  121 QEIQKKPSQQ VS