YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MET4

General Information:
Name(s) found: MET4 / YNL103W [SGD]
Description(s) found:
Found 15 descriptions.
SHOW ALL
  • Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 672 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IPILink to PubMed article]
    Biological Process: sulfur amino acid metabolic process [IMPLink to PubMed article]
    response to arsenic [IDALink to PubMed article]
    response to cadmium ion [IDALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    Molecular Function: transcription coactivator activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQEQSHEGD SYSTEFINLF GKDTATHPSS NNGANNNGMG STNSLDQFVA TASSSSSLVT  60
   61 SSENRRPLIG DVTNRGNTNL YDHAVTPEIL LEQLAYVDNF IPSLDNEFSN VDWNVNTTHN 120
  121 NANNNGADTF SSINANPFDL DEQLAIELSA FADDSFIFPD EDKPSNNNNN SNNGNDDHSN 180
  181 HDVLHEDPST NNRQRNPHFL TQRRNTFLTS QYDQSKSRFS SKNKRNGNNG ETNNFGDNMQ 240
  241 NNHPFEPNFM GSPSQFPADA TNMTSIDHGG FTNVDITSTE NNTTGDNGVD ALSNLLHRTT 300
  301 HTPNRSSPLS NVTSAQNSSS QQRKHSESKV DSNSDNNSSN KAPNITVPDY SIIPTSVLVT 360
  361 LLPRVNVPNG AYNSLISAGF DNDQIDAIAA IMAYHHQKKI RENNSNNNKN INTNDSQEAP 420
  421 ILKNINELLS VLIPPSPAET RGPTTLSTSP SFNEHGVVAE ASFLSSILEL GIKHPKSNNI 480
  481 HNQRQPSRND HKISRESDGN NGNDNVHHNN AVIKSSTTRG DEIAKIRSEP TLNASSSDHK 540
  541 ENSLKRSHSG DLKNKKVPVD RKYSDNEDDE YDDADLHGFE KKQLIKKELG DDDEDLLIQS 600
  601 KKSHQKKKLK EKELESSIHE LTEIAASLQK RIHTLETENK LLKNLVLSSG ETEGIKKAES 660
  661 LKKQIFEKVQ KE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) CBF1 MET28 MET31 MET32 MET4
    View Details Krogan NJ, et al. (2006) GLN3 MET4 URE2
    View Details Ho Y, et al. (2002) CDC53 MET30 MET31 MET4 RUB1 SIS1 SKP1 TEF4 UBI4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] deduced N/A No confident structure predictions are available.
    2 View Details [175..551] ORFEUS 11.42 RBP1
    3 View Details [552..672] ORFEUS 8.01 Sec24


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle