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Protein Overview: TCM62

General Information:
Name(s) found: TCM62 / YBR044C [SGD]
Description(s) found:
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  • gi|6319518|ref|NP_009600.1| Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone; Tcm62p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S45902 probable membrane protein YBR044c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|536270|emb|CAA84986.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • TCM62 Chaperone required for assembly of mitochondrial succinate dehydrogenase [mips]
  • Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone [SGD]
  • TCM62, Chr II from 324298-326019, reverse complement [yeast_orfs2]
  • Chr II from 324298-326019, reverse complement [yeastorf3.fasta]
  • Chr II from 326019-324298, reverse complement [yeastorf5.fasta]
  • (P38228) Mitochondrial chaperone TCM62 [4932.FASTACCERV.txt]
  • TCM62 SGDID:S0000248, Chr II from 326020-324299, reverse complement, Verified ORF [yeastflysequest.fasta]
  • TCM62 SGDID:S0000248, Chr II from 326058-324337, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Tcm62p [Saccharomyces cerevisiae]gi|536270|emb|CAA84986.1| unnamed protein product [Saccharomyces cerevisiae]gi|626213|pir||S45902 probable membrane protein YBR044c - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas]
  • TCM62 SGDID:S000000248, Chr II from 326058-324337, reverse complement, Verified ORF, "Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone; Tcm62p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: protein complex assembly [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: unfolded protein binding [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRNCLRKLG NHQTKCSVKT LHTPIYRTKN LQVLRDTLSG IKLLEKIITS SSYNKTLIYE  60
   61 PKYKSKPQVV SSHDTMRLHN VMRELLDSLQ VDEATNTRLQ SNRPRKLGRV GLQLFMDCIQ 120
  121 DNLTATSTSL TCSLLEHYFK YPEKEVTNGI KAGLRYIRDF LAKNKIIVKS QNDVDALVEQ 180
  181 LTMSSSDSQS IKRVLKAINY ELFSDDIVRV INGNKTYDEV DVSKGWKYPA GILDSNEAYL 240
  241 RSLELPTKKL VSIDKDMLVL MYDGTLRDAN KILPTITYAR KLRKSVLLIV NGDCTGDALT 300
  301 SVTINNNRNK RENNESRIVV LKYSKKANND LAPQENLDFI KFLRLPCGYD SIYSPEYSPL 360
  361 VPSKMCADKY YGSIESIKAT TGEAFLYNSI DAEAIPNKVP KSFLQNTVTL SIGGHNEIEI 420
  421 DRRRNAIDNC LNNVLCHGLA KGFIPGYGIS LLKAIPGLNE LKANEPNFMT KVGINAVLSA 480
  481 VILPSEVAFK NAYGYNYYEI NSLIAGAINE KSFPMAKFSP NSEPVNTVKD GNLEPWSKMD 540
  541 SCLAGVETFI ELLTSCNTII TCVYKSLNGT KPR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CTP1 ERV25 FKS1 FTR1 MRH1 OLE1 PEX27 ROG3 RPL10 RPL36B RPL37A RPP1A SEC11 SPC1 SPC2 SPC3 TCM62 TSC13 YNR021W
    View Details Gavin AC, et al. (2002) APM1 CYM1 DOA4 DUR1,2 HSP42 LAT1 LPD1 PDA1 PDB1 PDX1 PRP46 RPN11 TCM62
    View Details Qiu et al. (2008) PET100 TCM62

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167]
    [439..573]    		 PSI-BLAST 214.0 GroEL, E domain; GroEL, A domain; GroEL, I domain
    2 View Details [168..438] PSI-BLAST 214.0 GroEL, E domain; GroEL, A domain; GroEL, I domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle