Protein Overview: ERP2

General Information:
Name(s) found:	ERP2 / YAL007C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731264\|sp\|P39704.1\|ERP2_YEAST RecName: Full=Protein ERP2; Flags: Precursor [NCBI NR] gi\|6319312\|ref\|NP_009395.1\| Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; Erp2p [Saccharomyces [NCBI NR] pir\|\|S43448 FUN54 protein precursor - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|45270222\|gb\|AAS56492.1\| YAL007C [Saccharomyces cerevisiae] [NCBI NR] gi\|349746\|gb\|AAC04951.1\| Yal007cp [Saccharomyces cerevisiae] [NCBI NR] Protein ERP2 OS=Saccharomyces cerevisiae GN=ERP2 PE=1 SV=1 [Swiss-Prot] ERP2 P24 protein involved in membrane trafficking [mips] Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles [SGD] ERP2, Chr I from 137696-138343, reverse complement [yeast_orfs2] Chr I from 137696-138343, reverse complement [yeastorf3.fasta] Chr I from 137700-138347, reverse complement [yeastorf4.fasta] Chr I from 138347-137700, reverse complement [yeastorf5.fasta] (P39704) ERP2 protein precursor [4932.FASTACCERV.txt] ERP2 SGDID:S0000005, Chr I from 138349-137702, reverse complement, Verified ORF [yeastflysequest.fasta] ERP2 SGDID:S0000005, Chr I from 138347-137700, reverse complement, Verified ORF [10112005cervSGD.fasta] Erp2p [Saccharomyces cerevisiae]gi\|630000\|pir\|\|S43448 FUN54 protein precursor - yeast (Saccharomyces cerevisiae)gi\|45270222\|gb\|AAS56492.1\| YAL007C [Saccharomyces cerevisiae]gi\|349746\|gb\|AAC04951.1\| Yal007cp [Saccharomyces cerevisiae]gi\|731264\|sp\|P3970 [nrdb_11152004_Chlamydomonas] ERP2 SGDID:S000000005, Chr I from 138347-137700, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and l [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Yal007cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YAL007C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein ERP2 precursor [nr-271106-contam.fasta] Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles; Erp2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] ERP2 SGDID:S000000005, Chr I from 138347-137700, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" [yeast-bovrabprots.fasta] [chemostatdb.fasta] ERP2 SGDID:S0000005, Chr I from 138347-137700, reverse complement [DAS20-2-Contrast.fasta] Protein ERP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERP2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] ERP2 SGDID:S000000005, Chr I from 138345-137698, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" [yeast-030211-contam.fasta] ERP2 SGDID:S000000005, Chr I from 138345-137698, Genome Release 64-2-1, reverse complement, Verified ORF, "Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP2 has a paralog, ERP4, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR817\|c0_g1_i1\|g.542 ORF TR817\|c0_g1_i1\|g.542 TR817\|c0_g1_i1\|m.542 type:complete len:216 (+) TR817\|c0_g1_i1:112-759(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YAL007C SGDID:S000000005, Chr I from 138345-137698, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_9685\|g.6976 ORF asmbl_9685\|g.6976 asmbl_9685\|m.6976 type:complete len:216 (+) asmbl_9685:109-756(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_9691\|g.5838 ORF ID=asmbl_9691\|g.5838 ID=asmbl_9691\|m.5838 type:complete len:216 (+) ID=asmbl_9691:109-756(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	215 amino acids
Gene Ontology:
Cellular Component:	ER to Golgi transport vesicle [IDA]
Biological Process:	ER to Golgi vesicle-mediated transport [IPI]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSTIALPS FFIVLILALV NSVAASSSYA PVAISLPAFS KECLYYDMVT EDDSLAVGYQ  60
   61 VLTGGNFEID FDITAPDGSV ITSEKQKKYS DFLLKSFGVG KYTFCFSNNY GTALKKVEIT 120
  121 LEKEKTLTDE HEADVNNDDI IANNAVEEID RNLNKITKTL NYLRAREWRN MSTVNSTESR 180
  181 LTWLSILIII IIAVISIAQV LLIQFLFTGR QKNYV

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		EMP24 ERP1 ERP2 ERV25
View Details	(MIPS) Mewes HW, et al. (2004)		EMP24 ERP1 ERP2 ERV25 ERV46 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31
View Details	Krogan NJ, et al. (2006)		EMP24 ERP1 ERP2 KAR2 PHB2 SCJ1 SSS1 YEL1
View Details	Gavin AC, et al. (2006)		EMP24 ERP1 ERP2 ERV25
View Details	Gavin AC, et al. (2002)		ARO1 ARX1 EMP24 ERP1 ERP2 ERV25 FKS1 HAS1 HHF1, HHF2 KAP123 NIP7 PHB1 RRP1
View Details	Qiu et al. (2008)		EMP24 ERP1 ERP2 ERV25 ERV41 ERV46 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31 SFB3 YOS1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SAM35	ERP2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	ERP2	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..215]	Pfam	75.124939	emp24/gp25L/p24 family/GOLD No confident structure predictions are available.
2	View Details	[146..215]	MSA	5.210997	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2