YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FPR3
Organism: Saccharomyces cerevisiae
Length: 411 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FPR3.

Description E-value Query
Range
Subject
Range
gi|2231720 - gi|2231720|gb|AAC45693.1| macrophage infectivity potentiator [Legionella jordanis]
2.0E-69 [185..410] [23..247]
FPR3 - Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by cas...
FKBP3_YEAST - FK506-binding nuclear protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FPR3 PE=1 ...
5.0E-68 [1..411] [1..411]
gi|6958238 - gi|6958238|gb|AAF32509.1|AF095230_1 macrophage infectivity potentiator [Legionella pneumophila]
8.0E-68 [200..410] [21..230]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-67 [200..410] [21..230]
gi|2231692 - gi|2231692|gb|AAC45674.1| macrophage infectivity potentiator [Fluoribacter dumoffii]
3.0E-67 [200..410] [21..230]
gi|2231682 - gi|2231682|gb|AAC45669.1| macrophage infectivity potentiator [Legionella anisa]
3.0E-67 [196..410] [16..229]
gi|2231688 - gi|2231688|gb|AAC45672.1| macrophage infectivity potentiator [Legionella cherrii]
8.0E-67 [200..410] [21..230]
gi|2231686 - gi|2231686|gb|AAC45671.1| macrophage infectivity potentiator [Fluoribacter bozemanae]
8.0E-67 [198..410] [19..230]
gi|2231736 - gi|2231736|gb|AAC45701.1| macrophage infectivity potentiator [Legionella parisiensis]
1.0E-66 [200..410] [21..230]

Back

Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDLLPLATY SLNVEPYTPV PAIDVTMPIT VRITMAALNP EAIDEENKPS TLRIIKRNPD  60
   61 FEDDDFLGGD FDEDEIDEES SEEEEEEKT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.75
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted functions:

Term Confidence Notes
histone binding 3.35045437512493 bayes_pls_golite062009
binding 2.31105760892804 bayes_pls_golite062009
protein binding 2.12153134547445 bayes_pls_golite062009
unfolded protein binding 1.82337497151874 bayes_pls_golite062009
transcription regulator activity 1.64766838528772 bayes_pls_golite062009
DNA binding 1.44751295983711 bayes_pls_golite062009
transcription activator activity 1.24287805928534 bayes_pls_golite062009
nucleic acid binding 1.22112424514163 bayes_pls_golite062009
transcription factor binding 0.771629017736754 bayes_pls_golite062009
enzyme binding 0.420979974123408 bayes_pls_golite062009
hydrolase activity 0.319361545733709 bayes_pls_golite062009
catalytic activity 0.290929394811364 bayes_pls_golite062009
ribonucleoprotein binding 0.290017406252516 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.237741029116502 bayes_pls_golite062009
pyrophosphatase activity 0.196866743343878 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.186970052809736 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.1843930975799 bayes_pls_golite062009
ATPase activity, coupled 0.0973531211151839 bayes_pls_golite062009
NF-kappaB binding 0.00132024988427304 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKKKKSKGKK AESESEDDEE DDDEDDEFQE SVLLTLSPEA QYQQSLDLTI TPEEEVQFIV  60
   61 TGSYAISLSG NYVKHPFDT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.75
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted functions:

Term Confidence Notes
ryanodine-sensitive calcium-release channel activity 10.9968443145942 bayes_pls_golite062009
intracellular ligand-gated calcium channel activity 10.9968443145942 bayes_pls_golite062009
macrolide binding 7.31599503004442 bayes_pls_golite062009
FK506 binding 7.22442625476031 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.74926751944787 bayes_pls_golite062009
calcium channel activity 6.4374377859142 bayes_pls_golite062009
cation channel activity 6.06732269872248 bayes_pls_golite062009
ion channel activity 5.45007096522107 bayes_pls_golite062009
passive transmembrane transporter activity 5.32426176964634 bayes_pls_golite062009
channel activity 5.32426176964634 bayes_pls_golite062009
substrate-specific channel activity 5.28960420749143 bayes_pls_golite062009
gated channel activity 5.28074654906904 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 4.0615867467963 bayes_pls_golite062009
cis-trans isomerase activity 3.99265212272703 bayes_pls_golite062009
ligand-gated channel activity 3.34717828007833 bayes_pls_golite062009
ligand-gated ion channel activity 3.34717828007833 bayes_pls_golite062009
ion transmembrane transporter activity 2.6566793500337 bayes_pls_golite062009
cation transmembrane transporter activity 2.61794461605199 bayes_pls_golite062009
calcium-release channel activity 2.58969194870156 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.47257819150887 bayes_pls_golite062009
isomerase activity 2.31710030777753 bayes_pls_golite062009
transcription regulator activity 1.85589011277711 bayes_pls_golite062009
receptor activity 1.78361575899771 bayes_pls_golite062009
transmembrane receptor activity 1.7459556028988 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.68688812199737 bayes_pls_golite062009
kinase activity 1.67904764195462 bayes_pls_golite062009
binding 1.63170667962375 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.57898291235576 bayes_pls_golite062009
signal transducer activity 1.53711974553033 bayes_pls_golite062009
molecular transducer activity 1.53711974553033 bayes_pls_golite062009
protein kinase activity 1.45320632553313 bayes_pls_golite062009
drug binding 1.39643621593407 bayes_pls_golite062009
transferase activity 1.34122735969662 bayes_pls_golite062009
receptor serine/threonine kinase binding 1.32709321745178 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 1.32470025150272 bayes_pls_golite062009
transforming growth factor beta receptor binding 1.32470025150272 bayes_pls_golite062009
transporter activity 1.25197125648774 bayes_pls_golite062009
protein binding 1.08765413491791 bayes_pls_golite062009
SMAD binding 1.04905381164355 bayes_pls_golite062009
transmembrane transporter activity 1.03909235910355 bayes_pls_golite062009
catalytic activity 0.885282592863018 bayes_pls_golite062009
substrate-specific transporter activity 0.789390402522536 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.780499202755666 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase activity 0.763739321802433 bayes_pls_golite062009
transforming growth factor beta receptor activity 0.763739321802433 bayes_pls_golite062009
intracellular ligand-gated ion channel activity 0.727019445105701 bayes_pls_golite062009
protein serine/threonine kinase activity 0.671059013500415 bayes_pls_golite062009
activin binding 0.33489895389042 bayes_pls_golite062009
unfolded protein binding 0.27473817613726 bayes_pls_golite062009
histone binding 0.221748741603068 bayes_pls_golite062009
transcription elongation regulator activity 0.21145105012677 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [169-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMGVEGEDED EDADIYDSED YDLTPDEDEI IGDDMDDLDD EEEEEVRIEE VQEEDEEDND  60
   61 GEEEQEEEEE 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.75
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [239-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEQKEEVKPE PKKSKKEKKR KHEEKEEEKK AKKVKKVEFK KDLEEGPTKP KSKKEQDKHK  60
   61 PKSKVLEGG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.75
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [308-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVIEDRTIGD GPQAKRGARV GMRYIGKLKN GKVFDKNTSG KPFAFKLGRG EVIKGWDIGV  60
   61 AGMSVGGERR IIIPAPYAYG KQALPGIPAN SELTFDVKLV SMKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 250.218487
Match: 1yat__
Description: Calcineurin (FKBP12.6)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle