| Protein: | FUN30 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1131 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUN30.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1131] | [1..1131] |
|
|
0.0 | [87..1116] | [10..1043] |
|
|
0.0 | [56..1116] | [89..1131] |
|
|
0.0 | [30..1119] | [94..1217] |
|
|
0.0 | [91..1131] | [1504..2545] |
|
|
0.0 | [19..1125] | [29..1096] |
|
Region A: Residues: [1-215] |
1 11 21 31 41 51
| | | | | |
1 MSGSHSNDED DVVQVPETSS PTKVASSSPL KPTSPTVPDA SVASLRSRFT FKPSDPSEGA 60
61 HTSKPLPSGS PEVALVNLAR EFPDFSQTLV QAVFKSNSFN LQSARERLTR LRQQRQNWTW 120
121 NKNASPKKSE TPPPVKKSLP LANTGRLSSI HGNINNKSSK ITVAKQKTSI FDRYSNVINQ 180
181 KQYTFELPTN LNIDSEALSK LPVNYNKKRR LVRAD
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [216-312] |
1 11 21 31 41 51
| | | | | |
1 QHPIGKSYES SATQLGSARE KLLANRKYGR HANDNDEEEE ESMMTDDDDA SGDDYTESTP 60
61 QINLDEQVLQ FINDSDIVDL SDLSDTTMHK AQLIASH
|
| Detection Method: | |
| Confidence: | 5.522879 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [313-365] |
1 11 21 31 41 51
| | | | | |
1 RPYSSLNAFV NTNFNDKDTE ENASNKRKRR AAASANESER LLDKITQSIR GYN
|
|
Region B: Residues: [452-521] |
1 11 21 31 41 51
| | | | | |
1 AEPTPAPAPA PVERETKRIR NTTKPKVVED EDDDVDLEAI DDELPQSEHE DDDYEEEDED 60
61 YNDEEEDVEY
|
| Detection Method: | |
| Confidence: | 5.522879 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleic acid binding | 3.89165617439497 | bayes_pls_golite062009 |
| DNA binding | 3.38561002225202 | bayes_pls_golite062009 |
| structure-specific DNA binding | 2.99888727194073 | bayes_pls_golite062009 |
| single-stranded DNA binding | 2.93712042261633 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.43759174701552 | bayes_pls_golite062009 |
| structural molecule activity | 2.08258913217268 | bayes_pls_golite062009 |
| transcription regulator activity | 1.69669059514663 | bayes_pls_golite062009 |
| translation regulator activity | 1.46320772716954 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 1.40718318783582 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 1.35850109411274 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 1.35845277283398 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 1.35845277283398 | bayes_pls_golite062009 |
| protein binding | 1.20309946451799 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.96756670903925 | bayes_pls_golite062009 |
| transcription activator activity | 0.889401463702631 | bayes_pls_golite062009 |
| transcription factor activity | 0.859071050218437 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 0.844320909398101 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.77755643935497 | bayes_pls_golite062009 |
| ribonuclease activity | 0.702449673647117 | bayes_pls_golite062009 |
| telomeric DNA binding | 0.52700145953711 | bayes_pls_golite062009 |
| ligase activity | 0.346041081217685 | bayes_pls_golite062009 |
| RNA binding | 0.18502033889261 | bayes_pls_golite062009 |
| aspartate-tRNA ligase activity | 0.151650064901878 | bayes_pls_golite062009 |
| nuclease activity | 0.111225677144242 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 0.108195560803799 | bayes_pls_golite062009 |
|
Region A: Residues: [366-451] |
1 11 21 31 41 51
| | | | | |
1 AIESVIKKCS SYGDLVTSQM KKWGVQVEGD NSELDLMNLG EDDDDDNDDG NNDNNNSNNN 60
61 NTAGADATSK EKEDTKAVVE GFDETS
|
|
Region B: Residues: [522-771] |
1 11 21 31 41 51
| | | | | |
1 DDGDDDDDDD DEFVATRKNT HVISTTSRNG RKPIVKFFKG KPRLLSPEIS LKDYQQTGIN 60
61 WLNLLYQNKM SCILADDMGL GKTCQVISFF AYLKQINEPG PHLVVVPSST LENWLREFQK 120
121 FAPALKIEPY YGSLQEREEL RDILERNAGK YDVIVTTYNL AAGNKYDVSF LKNRNFNVVV 180
181 YDEGHMLKNS TSERFAKLMK IRANFRLLLT GTPLQNNLKE LMSLLEFIMP NLFISKKESF 240
241 DAIFKQRAKT
|
| Detection Method: | |
| Confidence: | 5.522879 |
| Match: | 1gm5A_ |
| Description: | RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.11222585187695 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.02893949194171 | bayes_pls_golite062009 |
| pyrophosphatase activity | 1.97909493766908 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 1.95844964816653 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 1.95658009428828 | bayes_pls_golite062009 |
| DNA binding | 1.7904783386531 | bayes_pls_golite062009 |
| transcription regulator activity | 1.68903321260301 | bayes_pls_golite062009 |
| ATPase activity | 1.42257610975945 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.2155186842031 | bayes_pls_golite062009 |
| helicase activity | 1.16085745407703 | bayes_pls_golite062009 |
| RNA helicase activity | 1.02424782546779 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| hydrolase activity | 0.98565595572967 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.95986988363392 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.94128341275411 | bayes_pls_golite062009 |
| ATPase activity, coupled | 0.732723553251109 | bayes_pls_golite062009 |
| DNA helicase activity | 0.72881469450553 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.725611289205392 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.720649395550746 | bayes_pls_golite062009 |
| nucleotide binding | 0.717697610309727 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.713814218071151 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.713752628021599 | bayes_pls_golite062009 |
| transcription factor activity | 0.603758349693077 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.58862275163252 | bayes_pls_golite062009 |
| transcription activator activity | 0.537911793669378 | bayes_pls_golite062009 |
| GTPase activity | 0.437665353870877 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.407727781673696 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.396187998943318 | bayes_pls_golite062009 |
| microtubule motor activity | 0.38363601832205 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.22150712609541 | bayes_pls_golite062009 |
| ATP binding | 0.19169045543599 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.165732470448462 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.162060759063149 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.144154288308693 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.114463153989353 | bayes_pls_golite062009 |
| motor activity | 0.0492172159259601 | bayes_pls_golite062009 |
|
Region A: Residues: [772-852] |
1 11 21 31 41 51
| | | | | |
1 TDDNKNHNPL LAQEAITRAK TMMKPFILRR RKDQVLKHLP PKHTHIQYCE LNAIQKKIYD 60
61 KEIQIVLEHK RMIKDGELPK D
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.586 | d.68.3 | SirA-like |
| View | Download | 0.775 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.668 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.639 | d.58.43 | Mechanosensitive channel protein MscS (YggB), C-terminal domain |
| View | Download | 0.582 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.526 | a.60.8 | HRDC-like |
| View | Download | 0.488 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.477 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.466 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.449 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.442 | d.68.4 | YhbY-like |
| View | Download | 0.437 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.434 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.422 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.409 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.404 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.400 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.392 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.391 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.390 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.383 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.375 | d.94.1 | HPr-like |
| View | Download | 0.374 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.370 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.363 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.351 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.348 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.336 | g.44.1 | RING/U-box |
| View | Download | 0.335 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.326 | a.1.1 | Globin-like |
| View | Download | 0.326 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.312 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.301 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.299 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.299 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.294 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.290 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.290 | d.42.1 | POZ domain |
| View | Download | 0.289 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.288 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.286 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.278 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.278 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.276 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.275 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.274 | a.4.1 | Homeodomain-like |
| View | Download | 0.273 | d.68.3 | SirA-like |
| View | Download | 0.273 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.272 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.272 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.265 | a.60.8 | HRDC-like |
| View | Download | 0.265 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.264 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.263 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.263 | d.58.12 | eEF-1beta-like |
| View | Download | 0.260 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.257 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.257 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.253 | a.4.12 | TrpR-like |
| View | Download | 0.252 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.251 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.250 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.249 | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.249 | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.246 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.243 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.243 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.241 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.240 | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.239 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.239 | a.2.7 | tRNA-binding arm |
| View | Download | 0.236 | a.4.1 | Homeodomain-like |
| View | Download | 0.235 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.235 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.234 | a.64.1 | Saposin |
| View | Download | 0.234 | a.39.1 | EF-hand |
| View | Download | 0.233 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.233 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.230 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.230 | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.230 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.229 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.226 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.226 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.226 | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.224 | a.135.1 | Tetraspanin |
| View | Download | 0.224 | a.4.12 | TrpR-like |
| View | Download | 0.222 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.220 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.219 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.217 | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.213 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.211 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.210 | b.55.1 | PH domain-like |
| View | Download | 0.209 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.208 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.206 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.206 | a.4.12 | TrpR-like |
| View | Download | 0.205 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.205 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.203 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
|
Region A: Residues: [853-1065] |
1 11 21 31 41 51
| | | | | |
1 AKEKSKLQSS SSKNLIMALR KASLHPLLFR NIYNDKIITK MSDAILDEPA YAENGNKEYI 60
61 KEDMSYMTDF ELHKLCCNFP NTLSKYQLHN DEWMQSGKID ALKKLLKTII VDKQEKVLIF 120
121 SLFTQVLDIL EMVLSTLDYK FLRLDGSTQV NDRQLLIDKF YEDKDIPIFI LSTKAGGFGI 180
181 NLVCANNVII FDQSFNPHDD RQAADRAHRV GQT
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1066-1131] |
1 11 21 31 41 51
| | | | | |
1 KEVNITTLIT KDSIEEKIHQ LAKNKLALDS YISEDKKSQD VLESKVSDML EDIIYDENSK 60
61 PKGTKE
|
| Detection Method: | |
| Confidence: | 5.0 |
| Match: | 1d9xA_ |
| Description: | Nucleotide excision repair enzyme UvrB |
Matching Structure (courtesy of the PDB): |
|
