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Protein Overview: kis-PA

General Information:
Name(s) found: kis-PA / FBpp0077803 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene kismet is referred to in FlyBase by the symbol Dmel\kis (CG3696, FBgn0086902). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:210732..250795. It has the cytological map location 21B4-21B5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; segment specification; border follicle cell migration; antimicrobial humoral response. 127 alleles are reported. The phenotypes of these alleles are annotated with: leg; imaginal disc. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 5322 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    chromatin [IEA]
    Biological Process: blastoderm segmentation [IMP]
    chromatin assembly or disassembly [IEA]
    border follicle cell migration [IMP]
    antimicrobial humoral response [IMP]
    segment specification [IMP]
    Molecular Function: ATP binding [IEA]
    DNA binding [IEA]
    ATP-dependent helicase activity [ISS]
    chromatin binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGNAQNMFH GNHQGDPYYR YDAAAAAAAA AAANPRAMGP PGGYPPRHRP PHPLQQQPQY  60
   61 PSYQPTAENL YGLGAADHQA AMGLGVGVGV GAGMGDLSGW GAAPSVPGQA AAYPGAGLGA 120
  121 YGHPQAAPPS QQQRQSNASA YRQHMPAYGQ QDQQKLASYG AQQSMMAGYG SLAPQQQQQQ 180
  181 QPPTPQQQQQ AQQVQQQAQQ QQQQQQQQSQ QQARLPQHYP QAPGQHPLYP GVGAPTVQAG 240
  241 QPPTPQAYAH SPYGSPMQHQ PSRGAPQHVG YGHTGLDQAS AYGQHVPGGA PPGHHLSAQQ 300
  301 QQAAQQLGAH QQQQLQSQQQ QQAQQQQPHV SLMQQQQLPG AGLPPPHMGM PPSYGSHHQQ 360
  361 QQQQQQTQQQ QQQSAPPYMS SSKHQQAAAQ LNSSPQYRAP FPQLSPQMSP RPPTMSPHPQ 420
  421 MSPRPVGVSP AKPPPPQQQQ QQTQAQQPQQ VVSNQPSQHS IQGMVGLPSP RPQPPTSGAG 480
  481 GAGAKGPAPV AAPVNTLQAL EQMVMPSQAL GLPPMDYPSA YRSAVGPRMP ASPQQQQQQH 540
  541 QQWGAAHGAQ HLAALQQQQA QQQQQQVQQQ QQAPPQQQQQ AAMLQAQQQH HQQQLSMYGQ 600
  601 PMGQQPQTAQ QQVVPPVTSQ PPVVAASQQQ QQQQHQQQSL NDQLQHSIND IVGGGNSSGA 660
  661 TGGAQNQHQQ QPQLAAMSSP LHQQNLPNMH HLIQPTMETT QPTQQQQQTS QQQQQPQQPQ 720
  721 ATLTSPHHQQ MQHQSPIHQQ QQSPHHQQHL PSYNQSQQQF DPFANILGDN QPAASQQTMS 780
  781 PAHVSSPVPA QMQQQQHQTQ QQPSQQVPQS QQQQVSQPQQ QTQQQQPSTP SHHLSSILNE 840
  841 TANSNDSSTL AVAANDSNNS SSNSSTNSIV NNQPTSVHDS NSQSSINSSS NNQQQLLMDN 900
  901 TNSHGGNSES AQNAGVDVGL FDNNSMSSNS AAVAAVASNA ASAAAALLDS NSQSSNAEFE 960
  961 KNQSEGEGLG VVEGVIANET DLPQDENSVS KTQDITLSTE LPTIQDDLQE KPTAEMEQTQ1020
 1021 LGQSLGDLSK SLLEEPKTVE ESGEDKSQSA PGVAPPADPI IPVTQPPQQQ MPPIGMPMHP1080
 1081 IAPGYEAQAQ GQGHMPPMMP PYGGAPGMYP PYPMLHQQEI AALQQQIQEL YCMPPGHELQ1140
 1141 HQDKLMRMQE RLNLLTQHEV NDQCAGGPQC LLFQNVPPMY GPPGNPLLNQ QMVESPQVSS1200
 1201 TTGRGRGKSA NKPRKPRAKK GEKAQVGQQQ DLMDISGNVA MGAANAVSSI PTTQLPVSED1260
 1261 CVTQGAGDTS VVGMLEYSEG MGDLSQDVHS ANELDTSTDG SGKKKKPRKP RTPKDPNKPP1320
 1321 RDRTPKAKKP KDPNDPNSTE TPAAVKKRAG ASKRRKQYGE DGAEQTGEGS EVEDNKPLVP1380
 1381 KAGSADGEAE TTSGGTGVDG ESPDYDDIPV SKIPRGSNED EKEAEAGDET VDSVPDSAGD1440
 1441 PASTPSRRDR KRSTARSRRN ANSEEGGSAR KNRGSLSAKA LKKRRNRGRI VPESDGEDDT1500
 1501 LDRTPPPSPP PDSEMDSNKR RSSRNTQRKK YIDDVMLRFS DDENSLLVAS PVKKDKKPSA1560
 1561 NASNSNAGSD VEKTEPQSGA EGDAAQEVGE EKSNLPLDES SQLEASSSTS AVAEKERQIS1620
 1621 TDAANAAMSS KPNYVYINTG DEDSMVVQLV LAMRMGKREL ILDKPKEKAP EPKQDEEKSE1680
 1681 LDEATTDKPE GDEKFKTEGE SKKDLTDSEE TKLESSAMEV DSKEESEPDD SKKSDEDNKD1740
 1741 KDKMEVDDEV GKSDKESKPE EQSETVKTEE NSKAIEEDKS STVLTADHAK EPETVLEKME1800
 1801 VDEKANDDQS AVSKAEGSDE KSTDDSNPEE ATTEKNKESL EIEGEKERVK EGEESVKKEN1860
 1861 DEKTEADMEN KPEPVFIDVE EYFVKYRNFS YLHCEWRTEE ELLKGDRRVA AKIRRFQQKQ1920
 1921 SQQLNIFENI EDEPFNQDFT EVDRVLDMSV HTDETSGETT KHYLVKWKSL PYEDCTWELE1980
 1981 EDVDNDKIEQ YLRFNKIPQR SEWKSKKRPH PELWKKLEKT PVYKGGNSLR PYQLEGLNWL2040
 2041 KFSWYNTHNC ILADEMGLGK TIQSLTFVHS VYEYGIRGPF LVIAPLSTIP NWQREFEGWT2100
 2101 DMNVVVYHGS VTSKQMIQDY EYYYKTESGK VLKEPIKFNV LITTFEMIVT DYMDLKAFNW2160
 2161 RLCVIDEAHR LKNRNCKLLE GLRQLNLEHR VLLSGTPLQN NISELFSLLN FLEPSQFSSQ2220
 2221 EEFMSEFGSL RTEEEVNKLQ ALLKPMMLRR LKDDVEKSLA PKEETIIEVE LTNIQKKYYR2280
 2281 GILEQNFSFL KKGTTSANIP NLMNTMMELR KCCIHPYLLN GAEEQIQYDF KSQHGEDPES2340
 2341 YYKNLILSAG KMVLIDKLLP KLKANGHRVL IFSQMVRCLD ILEDYLVYRK YPFERIDGRI2400
 2401 RGNLRQEAID RYSKPGSDRF VFLLCTKAGG LGINLTAADT VIIYDSDWNP QNDLQAQARC2460
 2461 HRIGQRKMVK IYRLLCRNTY EREMFDKASM KLGLDKAVLQ SMNTQGSKDG NNKQLSKKEI2520
 2521 EDLLKKGAYG AVMDDDNAGD KFCEEDIDSI LKRRTQVITM ESEKGSTFSK ASFAASGNRS2580
 2581 DITIDDPDFW TKWAKKVDID PDACERDETE DLVLSEPRRR TQIKRYGHED VMELNSEESS2640
 2641 NENSDEEGGI GLRSRRRKEK RDRAREKKGN DEYIPRERDA LAALGLEEIQ YGNWAKSECF2700
 2701 KVEKGLLSFG WGRWSELLEL GQFKRGWRDV DVEDCARIIL LYCLQVYKGD EKIKTFIWDL2760
 2761 ITPTEDGEVQ KISRDHSGLH NLVPRGRNGG KSNKESTGVS TPAPGSASGS NSGNTTPAHK2820
 2821 SSALDGSDKD SGGINASAVA AAVTSIHDPN HWSKKEKYDA DAYLEGAYKK HLGRHANKVL2880
 2881 LRVRMLYYIQ HEVIGDFVQQ IKDNTPISEL PIRPPPTPDQ VPSSWWNPIC CDKSLLVGTY2940
 2941 KHGCEMYRQM RADPNLCFVT HVGAGAAGDD LAVTSLPINE DDANSKHDDG DEVDDDGTTT3000
 3001 TKDSDSTKLT GGDNKDSLLD PERPSSSGLD EEESVAGSYP PTVAAVEDAT TMWPSMQDLN3060
 3061 TRLRRVITAY QRNYKKEELK LQQKAKLQAL VSSTPPLSVP TTPTLQSMQM QLQSGSGSGG3120
 3121 SGIGSSAQHD ASGRSLQALM QSQGASTSAA AAAAASSAGG SCSGSGQVGM GGAGVMPAMP3180
 3181 TAADISLMLS ILNTTDVNQL ANLDINKLAM YLVSMNNKME RQGKMELAAK ERESQRLQLI3240
 3241 PKKWNRREEY EFLRVLTGYG VDLHVSTPMA SSNGSSLSPD WTKFKQMAHL ERKSDETLTD3300
 3301 YYKVFVAMCK RQAGLKLSES ERGLEGIIEE IEKEHAKLIL DRLEVLAKLR EVARNPMLEE3360
 3361 RLKLCTKNAD TPDWWEPGRH DKELITAVLK HGLYRSETFI FNDPNFSFGE SEKRFIRELE3420
 3421 AQIQRTIKLE AFNAEKAEKL AAAEKDAATE KAAATEKAAA EKAASVKNEV IDLDDELMTN3480
 3481 ESVIKKESPV TPIKEEIKSE ESPEKHDTAD NLEDKNSDAE ESTKIKGKED FNPETTEKEA3540
 3541 LDESTNLNKD KSSTETLVPE IEDSKPSEDK MEVEELPVAE NGEKEGSPEK CSDAEDKKFS3600
 3601 EEKPSSPAVP DGKVSEMEAD EAAPNTEENC SGDSESPEKE CEDKVVEKVE EEKGENSYEK3660
 3661 AEEQKEETEK LEKSSIESEP SEKSETVLEP EVAVPKKSTG DQDILDLVAG PSDPDDDEVM3720
 3721 KEKEKAVEEE CKKQAAELKA RFPDLEVIQP ATVKQQKLEK PKLEMCMIRW FKDFALERRI3780
 3781 AHIVACVESG NWPVDSKYSA FATCKGATDL SIALHESIPH LSSLERRSTT PDVITITTDQ3840
 3841 GVTKHLQTSH MQQVASSASA ASTSSGVPQV TQSKPSSSNS LPGLDAKSIN AAVAAAVAAA3900
 3901 AAGGNATSLS SLLPGMSLSA ATGSSAGGVS GLSVPSAGSG VGKKRKRHIA IDVETERAKL3960
 3961 HALLNSSTMA PKDWESEIAN MEALSGSSGR GRGGNSSASS GMQPPPAHQH ASLSRQSSGQ4020
 4021 FSKPAVPAMK TPPPSMGAPM DLSSSLPKMN MTEMLKSASS SGAIDLSEVQ DFSMPSKKSS4080
 4081 VHAALSSAFP SMGNKSKLDD TLNKLMKKNN CTIEEPVIGK EKKRKKLDEI VLGLSAAKEQ4140
 4141 KTFPDPSLPS SKKPQIPPSV SVTPANLQSS SNQQSNQKPF TITVTTVPGK SKSGSSNSGS4200
 4201 GTGGSSSASG GGAGGSGLSA LQNMAMGGLS SKDSLNALLA QTMATDPQTF LKQQQKMMQF4260
 4261 LPPAQRKAYE NMLAEMEQAM KISSKFSTNS PHDVKVNKWL SDMTSPLGDQ LSIDYVGGGG4320
 4321 ASGSGSGNSR RSNRQQGNSQ QSSSAAQLQK QQQQQQQQQQ QQQQHSMPGP QNLTGEEPVP4380
 4381 VINKQTGKRL GGNKAPQLKR LMQWLTENPN YEVDPKWLEQ MQNPMSTPSP RPASMESGYG4440
 4441 SSAVKSHGGR PLSNLSSTSS SSHTQQQSSA AQSQAGGNSG SSKKNSRQQT AASAALDQAA4500
 4501 LQFGSLAGLN PSLLANLPGL GAFDPKNPLA AFDPKNPLLS MSFGGMPGMG NIPGLGNLNN4560
 4561 MNLFASLAGM GGLGNLAGMD TQSLAALMAA AGPTLGGLTG ASGGAGSGKS QAQSQSSATS4620
 4621 SSSSASKKKQ QQQQQQAQNE AAQLAAAISA STGGSGASGG KNAAASASQL AAGFPFLFPN4680
 4681 PSLLYPPMGL GGLNPYSLGS SGLGSAYDQL AQQYNLLNGA TSSASNTSST QSKSHQSQSK4740
 4741 SSQSRNTTAS ANSAASLMNA MASMGGGAST VTTPSTSASG SGRGRQSSSR NQSQTTPTAA4800
 4801 DMAQLSSLLM PGADPHLLES LSRMSNMDLA QATRLMSSLG MPPLSGTPSS SGGGNTSTSK4860
 4861 RSSQAANEAN VQAKEQQKWL ESLARGALPT DLAALQAFSQ GKMPSTSGSN TGTSTSSSKS4920
 4921 SKAAATAAAA QLPQIPGMSS DFPQAFLAEM AAQAMAAAGG SLPLSGPGSL ASLAGLTGGS4980
 4981 AGGGGSSASG STSHSSSKRQ REQDAFKQQM DYYTKTLGLG SGISLIPTSS AGGSSASSSA5040
 5041 ANAAAAAYAA ALDAEQQHQQ QQKALSKRAR GDLHPTKEEL AALAAGLPLN LGASMSSIEK5100
 5101 SLRGGSSSSS SSTPAPMTAE QDKVTLTPLN ASGGGSGSSS SSAAAAGLAA NLPSQTTITI5160
 5161 APPISSGAST SSERSERSES RISLTITNAA DAAKLPPPYE EADELIIQPI LKKPTAANPG5220
 5221 SSHGGSVDDL DTAENTSAAN LSGSSSSSAA AAAAAAAEEN RRSSNRLKRP RSGNEQGSGS5280
 5281 VEGQPPEKRR ELRSTRHTRS SADASTLNLS TGSESGAEER NE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.28

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle