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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ksp1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARO1
  • cytoplasm
  • aromatic amino acid family biosynthetic process
  • shikimate kinase activity
  • 3-dehydroquinate dehydratase activity
  • 3-phosphoshikimate 1-carboxyvinyltransferase activity
  • 3-dehydroquinate synthase activity
  • shikimate 5-dehydrogenase activity
  • BCK1
  • intracellular
  • response to acid
  • endoplasmic reticulum unfolded protein response
  • intracellular protein kinase cascade
  • response to nutrient
  • protein amino acid phosphorylation
  • MAP kinase kinase kinase activity
  • CHS1
  • chitosome
  • plasma membrane
  • cytokinesis, completion of separation
  • cell budding
  • chitin synthase activity
  • CMP2
  • calcineurin complex
  • cytoplasm
  • adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
  • cellular ion homeostasis
  • calcium-dependent protein serine/threonine phosphatase activity
  • DBP7
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • KOG1
  • fungal-type vacuole membrane
  • mitochondrion
  • TORC1 complex
  • plasma membrane
  • regulation of cell growth
  • cellular response to starvation
  • molecular_function
  • KSP1
  • nucleus
  • protein amino acid phosphorylation
  • protein serine/threonine kinase activity
  • PRI2
  • nuclear envelope
  • nucleus
  • alpha DNA polymerase:primase complex
  • DNA replication initiation
  • lagging strand elongation
  • DNA replication
  • DNA synthesis involved in DNA repair
  • DNA replication, synthesis of RNA primer
  • DNA primase activity
  • PSY2
  • nucleus
  • response to drug
  • response to DNA damage stimulus
  • molecular_function
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein serine/threonine phosphatase complex 3.0531E-4 10 17 2 6292
    chitosome 3.1764E-3 10 2 1 6292
    calcineurin complex 6.3436E-3 10 4 1 6292
    protein phosphatase type 2A complex 9.5019E-3 10 6 1 6292
    TORC1 complex 9.5019E-3 10 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular response to stimulus 1.5127E-4 10 379 5 6292
    cellular response to stress 7.4443E-4 10 290 4 6292
    response to extracellular stimulus 1.5503E-3 10 38 2 6292
    response to nutrient levels 1.5503E-3 10 38 2 6292
    response to external stimulus 1.5503E-3 10 38 2 6292
    response to stimulus 3.9288E-3 10 766 5 6292
    phosphorus metabolic process 4.7228E-3 10 229 3 6292
    phosphate metabolic process 4.7228E-3 10 229 3 6292
    response to stress 5.4959E-3 10 497 4 6292
    signaling 6.1793E-3 10 252 3 6292
    DNA synthesis involved in DNA repair 6.3436E-3 10 4 1 6292
    DNA replication, synthesis of RNA primer 7.9239E-3 10 5 1 6292
    cell budding 8.4509E-3 10 90 2 6292
    asexual reproduction 8.4509E-3 10 90 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    3-dehydroquinate dehydratase activity 1.5893E-3 10 1 1 6292
    3-dehydroquinate synthase activity 1.5893E-3 10 1 1 6292
    shikimate 5-dehydrogenase activity 1.5893E-3 10 1 1 6292
    3-phosphoshikimate 1-carboxyvinyltransferase activity 1.5893E-3 10 1 1 6292
    shikimate kinase activity 1.5893E-3 10 1 1 6292
    transferase activity, transferring phosphorus-containing groups 2.9742E-3 10 420 4 6292
    phosphotransferase activity, alcohol group as acceptor 3.1275E-3 10 198 3 6292
    DNA primase activity 3.1764E-3 10 2 1 6292
    kinase activity 4.3266E-3 10 222 3 6292
    transferase activity 4.6862E-3 10 797 5 6292
    chitin synthase activity 4.7611E-3 10 3 1 6292
    carbon-oxygen lyase activity, acting on phosphates 4.7611E-3 10 3 1 6292
    calcium-dependent protein serine/threonine phosphatase activity 4.7611E-3 10 3 1 6292
    protein serine/threonine kinase activity 8.6334E-3 10 91 2 6292
    MAP kinase kinase kinase activity 9.5019E-3 10 6 1 6292
    acetylglucosaminyltransferase activity 9.5019E-3 10 6 1 6292

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