YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Gdi1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GDI1
  • membrane fraction
  • soluble fraction
  • vesicle-mediated transport
  • Rab GDP-dissociation inhibitor activity
  • SEC4
  • incipient cellular bud site
  • mitochondrion
  • vesicle
  • transport vesicle
  • mitochondrial outer membrane
  • actin cap
  • vesicle fusion
  • bipolar cellular bud site selection
  • small GTPase mediated signal transduction
  • Golgi to plasma membrane transport
  • ascospore-type prospore formation
  • cytokinesis
  • exocytosis
  • membrane addition at site of cytokinesis
  • GTPase activity
  • STE11
  • cytoplasm
  • activation of MAPKK activity
  • MAPKKK cascade involved in osmosensory signaling pathway
  • pseudohyphal growth
  • osmosensory signaling pathway via Sho1 osmosensor
  • invasive growth in response to glucose limitation
  • signal transduction during filamentous growth
  • protein amino acid phosphorylation
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
  • SAM domain binding
  • MAP kinase kinase kinase activity
  • VPS21
  • mitochondrion
  • late endosome
  • mitochondrial outer membrane
  • endocytosis
  • protein targeting to vacuole
  • GTPase activity
  • YPT1
  • endoplasmic reticulum membrane
  • mitochondrion
  • Golgi membrane
  • ER to Golgi vesicle-mediated transport
  • protein complex assembly
  • GTPase activity
  • YPT10
  • cytoplasm
  • Golgi organization
  • GTPase activity
  • guanyl nucleotide binding
  • YPT31
  • endosome
  • Golgi apparatus
  • mitochondrial outer membrane
  • vesicle-mediated transport
  • exocytosis
  • GTPase activity
  • YPT32
  • endosome
  • Golgi apparatus
  • mitochondrial outer membrane
  • vesicle-mediated transport
  • exocytosis
  • GTPase activity
  • YPT52
  • late endosome
  • endocytosis
  • protein targeting to vacuole
  • GTPase activity
  • YPT6
  • Golgi apparatus
  • intracellular protein transport
  • retrograde transport, endosome to Golgi
  • GTPase activity
  • YPT7
  • mitochondrial outer membrane
  • vacuole
  • vacuole inheritance
  • vesicle-mediated transport
  • telomere maintenance
  • vacuole fusion, non-autophagic
  • endocytosis
  • Golgi to vacuole transport
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mitochondrial outer membrane 2.583E-7 11 92 5 6292
    outer membrane 6.8947E-6 11 178 5 6292
    organelle outer membrane 6.8947E-6 11 178 5 6292
    endosome 1.4231E-5 11 94 4 6292
    mitochondrial membrane 4.8735E-5 11 266 5 6292
    mitochondrial envelope 1.0477E-4 11 312 5 6292
    Golgi apparatus 1.4972E-4 11 171 4 6292
    organelle membrane 4.9182E-4 11 692 6 6292
    late endosome 6.2981E-4 11 22 2 6292
    mitochondrial part 7.5658E-4 11 475 5 6292
    envelope 1.0033E-3 11 505 5 6292
    organelle envelope 1.0033E-3 11 505 5 6292
    mitochondrion 6.5685E-3 11 1125 6 6292
    membrane 9.0464E-3 11 1198 6 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    vesicle-mediated transport 1.7722E-10 11 340 9 6292
    establishment of localization in cell 8.2132E-7 11 599 8 6292
    cellular localization 1.4234E-6 11 643 8 6292
    transport 2.4765E-6 11 997 9 6292
    establishment of localization 2.7247E-6 11 1008 9 6292
    localization 4.2181E-6 11 1060 9 6292
    exocytosis 5.7929E-5 11 46 3 6292
    secretion 9.3934E-5 11 54 3 6292
    secretion by cell 9.3934E-5 11 54 3 6292
    intracellular transport 1.4116E-4 11 553 6 6292
    cellular membrane organization 2.639E-4 11 198 4 6292
    membrane organization 2.639E-4 11 198 4 6292
    endocytosis 4.0225E-4 11 88 3 6292
    membrane invagination 4.8853E-4 11 94 3 6292
    vacuolar transport 8.8189E-4 11 115 3 6292
    Golgi vesicle transport 2.6346E-3 11 168 3 6292
    membrane addition at site of cytokinesis 3.4937E-3 11 2 1 6292
    osmosensory signaling pathway via Sho1 osmosensor 5.2364E-3 11 3 1 6292
    cellular membrane fusion 5.7748E-3 11 67 2 6292
    membrane fusion 5.7748E-3 11 67 2 6292
    post-Golgi vesicle-mediated transport 5.9441E-3 11 68 2 6292
    protein targeting to vacuole 6.1157E-3 11 69 2 6292
    ascospore-type prospore formation 6.9763E-3 11 4 1 6292
    Golgi organization 6.9763E-3 11 4 1 6292
    intracellular protein transport 8.5221E-3 11 255 3 6292
    activation of MAPKK activity 8.7135E-3 11 5 1 6292
    activation of protein kinase activity 8.7135E-3 11 5 1 6292
    protein transport 9.8755E-3 11 269 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    GTPase activity 2.2188E-17 11 61 9 6292
    nucleoside-triphosphatase activity 1.3177E-10 11 329 9 6292
    hydrolase activity, acting on acid anhydrides 2.4842E-10 11 353 9 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.4842E-10 11 353 9 6292
    pyrophosphatase activity 2.4842E-10 11 353 9 6292
    hydrolase activity 1.1275E-6 11 911 9 6292
    catalytic activity 1.6253E-4 11 2150 10 6292
    Rab GDP-dissociation inhibitor activity 1.7483E-3 11 1 1 6292
    GDP-dissociation inhibitor activity 3.4937E-3 11 2 1 6292
    SAM domain binding 5.2364E-3 11 3 1 6292
    protein domain specific binding 6.9763E-3 11 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle