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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 5.3738E-18 6 11 6 6292
replication fork 6.1016E-14 6 42 6 6292
chromosomal part 2.6859E-9 6 237 6 6292
chromosome 6.4695E-9 6 274 6 6292
intracellular non-membrane-bounded organelle 1.2371E-5 6 959 6 6292
non-membrane-bounded organelle 1.2371E-5 6 959 6 6292
protein complex 3.4445E-5 6 1137 6 6292
macromolecular complex 3.0579E-4 6 1635 6 6292
organelle part 2.2664E-3 6 2282 6 6292
intracellular organelle part 2.2664E-3 6 2282 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 2.1931E-13 6 15 5 6292
mismatch repair 5.8863E-12 6 27 5 6292
DNA strand elongation 1.2382E-11 6 31 5 6292
DNA strand elongation involved in DNA replication 1.2382E-11 6 31 5 6292
DNA replication 4.9427E-11 6 123 6 6292
DNA repair 7.4792E-10 6 192 6 6292
DNA-dependent DNA replication 1.9749E-9 6 82 5 6292
response to DNA damage stimulus 2.6179E-9 6 236 6 6292
sister chromatid cohesion 8.2088E-9 6 32 4 6292
cellular response to stress 9.1219E-9 6 290 6 6292
cellular response to stimulus 4.6012E-8 6 379 6 6292
response to stress 2.362E-7 6 497 6 6292
DNA metabolic process 6.3106E-7 6 585 6 6292
chromosome segregation 2.3759E-6 6 128 4 6292
response to stimulus 3.2E-6 6 766 6 6292
chromosome organization 2.9217E-5 6 555 5 6292
cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
nucleic acid metabolic process 1.283E-4 6 1415 6 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.3599E-4 6 1566 6 6292
cellular biosynthetic process 2.3689E-4 6 1567 6 6292
biosynthetic process 2.7052E-4 6 1602 6 6292
cell cycle process 4.8022E-4 6 490 4 6292
cellular nitrogen compound metabolic process 4.9256E-4 6 1770 6 6292
nitrogen compound metabolic process 5.2873E-4 6 1791 6 6292
cell cycle 6.2738E-4 6 525 4 6292
organelle organization 9.3483E-4 6 1127 5 6292
cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
cellular component organization 4.7462E-3 6 1582 5 6292
regulation of transposition, DNA-mediated 7.6075E-3 6 8 1 6292
negative regulation of transposition, DNA-mediated 7.6075E-3 6 8 1 6292
transposition, DNA-mediated 7.6075E-3 6 8 1 6292
negative regulation of transposition 8.5551E-3 6 9 1 6292
regulation of transposition 8.5551E-3 6 9 1 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein-DNA loading ATPase activity 1.5353E-15 6 7 5 6292
DNA clamp loader activity 1.5353E-15 6 7 5 6292
DNA-dependent ATPase activity 2.5271E-10 6 55 5 6292
ATPase activity, coupled 4.1022E-8 6 149 5 6292
ATPase activity 2.3635E-7 6 211 5 6292
DNA binding 6.2279E-7 6 256 5 6292
nucleoside-triphosphatase activity 2.1805E-6 6 329 5 6292
hydrolase activity, acting on acid anhydrides 3.0968E-6 6 353 5 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.0968E-6 6 353 5 6292
pyrophosphatase activity 3.0968E-6 6 353 5 6292
nucleic acid binding 7.1765E-5 6 666 5 6292
hydrolase activity 3.3278E-4 6 911 5 6292
purine nucleotide binding 9.8386E-4 6 52 2 6292
nucleotide binding 1.2657E-3 6 59 2 6292
binding 1.819E-3 6 1294 5 6292

YRC Informatics Platform - Version 3.0
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