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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • PPH22
  • condensed nuclear chromosome, centromeric region
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • G1/S transition of mitotic cell cycle
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • hydrolase activity
  • RRD2
  • cytosol
  • cell fraction
  • response to osmotic stress
  • mitotic spindle organization in nucleus
  • protein phosphatase type 2A regulator activity
  • RTS1
  • nucleus
  • condensed nuclear chromosome, centromeric region
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • protein phosphatase type 2A complex
  • protein amino acid dephosphorylation
  • meiotic sister chromatid cohesion, centromeric
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • TPD3
  • nucleus
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • spindle pole body
  • mating projection tip
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • protein amino acid dephosphorylation
  • actin filament organization
  • budding cell bud growth
  • translation
  • ZDS1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • nuclear pore
  • mRNA export from nucleus
  • chromatin silencing
  • cell aging
  • protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 2A complex 3.4469E-12 6 6 4 6292
    protein serine/threonine phosphatase complex 5.4538E-10 6 17 4 6292
    cellular bud neck 2.4513E-6 6 129 4 6292
    cellular bud 6.7281E-6 6 166 4 6292
    site of polarized growth 7.0577E-6 6 168 4 6292
    cellular bud tip 1.3832E-5 6 57 3 6292
    protein complex 9.756E-4 6 1137 5 6292
    condensed chromosome, centromeric region 1.1004E-3 6 55 2 6292
    condensed nuclear chromosome, centromeric region 1.1004E-3 6 55 2 6292
    microtubule organizing center 1.4423E-3 6 63 2 6292
    spindle pole body 1.4423E-3 6 63 2 6292
    chromosome, centromeric region 1.6301E-3 6 67 2 6292
    spindle pole 1.6787E-3 6 68 2 6292
    condensed nuclear chromosome 2.6729E-3 6 86 2 6292
    spindle 2.8601E-3 6 89 2 6292
    condensed chromosome 3.1857E-3 6 94 2 6292
    microtubule cytoskeleton 4.0352E-3 6 106 2 6292
    macromolecular complex 5.5477E-3 6 1635 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein amino acid dephosphorylation 4.6787E-9 6 28 4 6292
    dephosphorylation 2.082E-8 6 40 4 6292
    mitotic cell cycle spindle assembly checkpoint 6.369E-7 6 21 3 6292
    negative regulation of nuclear division 6.369E-7 6 21 3 6292
    negative regulation of mitosis 6.369E-7 6 21 3 6292
    negative regulation of mitotic metaphase/anaphase transition 6.369E-7 6 21 3 6292
    spindle assembly checkpoint 6.369E-7 6 21 3 6292
    negative regulation of cell cycle 7.372E-7 6 22 3 6292
    spindle checkpoint 1.0998E-6 6 25 3 6292
    regulation of mitotic metaphase/anaphase transition 1.0998E-6 6 25 3 6292
    mitotic cell cycle spindle checkpoint 1.0998E-6 6 25 3 6292
    M phase 1.244E-6 6 294 5 6292
    mitotic cell cycle checkpoint 1.5649E-6 6 28 3 6292
    negative regulation of cellular component organization 1.7448E-6 6 29 3 6292
    regulation of nuclear division 1.7448E-6 6 29 3 6292
    negative regulation of organelle organization 1.7448E-6 6 29 3 6292
    regulation of mitosis 1.7448E-6 6 29 3 6292
    negative regulation of cell cycle process 2.3659E-6 6 32 3 6292
    budding cell bud growth 2.8523E-6 6 34 3 6292
    mitotic metaphase/anaphase transition 3.6996E-6 6 37 3 6292
    cell cycle phase 4.2398E-6 6 376 5 6292
    regulation of organelle organization 1.0466E-5 6 52 3 6292
    cell cycle checkpoint 1.4581E-5 6 58 3 6292
    cell cycle process 1.5781E-5 6 490 5 6292
    cell cycle 2.2202E-5 6 525 5 6292
    actin filament organization 2.3597E-5 6 68 3 6292
    phosphorus metabolic process 2.4213E-5 6 229 4 6292
    phosphate metabolic process 2.4213E-5 6 229 4 6292
    cytoskeleton organization 2.5062E-5 6 231 4 6292
    regulation of mitotic cell cycle 2.6883E-5 6 71 3 6292
    regulation of cellular component organization 3.1714E-5 6 75 3 6292
    negative regulation of cellular process 3.428E-5 6 250 4 6292
    negative regulation of biological process 3.5937E-5 6 253 4 6292
    mitotic cell cycle 3.7074E-5 6 255 4 6292
    regulation of cell cycle process 3.9986E-5 6 81 3 6292
    cell budding 5.4879E-5 6 90 3 6292
    asexual reproduction 5.4879E-5 6 90 3 6292
    mitosis 8.4638E-5 6 104 3 6292
    nuclear division 8.96E-5 6 106 3 6292
    organelle fission 1.0847E-4 6 113 3 6292
    actin cytoskeleton organization 1.0847E-4 6 113 3 6292
    actin filament-based process 1.2034E-4 6 117 3 6292
    post-translational protein modification 1.3958E-4 6 357 4 6292
    M phase of mitotic cell cycle 1.5729E-4 6 128 3 6292
    regulation of cell cycle 1.6852E-4 6 131 3 6292
    translation 1.7103E-4 6 376 4 6292
    growth 2.2788E-4 6 145 3 6292
    cell division 2.2788E-4 6 145 3 6292
    protein modification process 5.1534E-4 6 499 4 6292
    signal transduction 7.192E-4 6 214 3 6292
    signal transmission 7.492E-4 6 217 3 6292
    signaling process 7.492E-4 6 217 3 6292
    reproduction of a single-celled organism 7.492E-4 6 217 3 6292
    macromolecule modification 8.5609E-4 6 569 4 6292
    organelle organization 9.3483E-4 6 1127 5 6292
    meiotic sister chromatid cohesion, centromeric 9.5359E-4 6 1 1 6292
    signaling 1.1606E-3 6 252 3 6292
    cellular macromolecule biosynthetic process 1.2008E-3 6 1187 5 6292
    macromolecule biosynthetic process 1.2106E-3 6 1189 5 6292
    gene expression 1.746E-3 6 1283 5 6292
    meiotic sister chromatid cohesion 1.9064E-3 6 2 1 6292
    reproduction 2.4954E-3 6 328 3 6292
    regulation of cellular process 3.0881E-3 6 796 4 6292
    regulation of biological process 3.5191E-3 6 824 4 6292
    negative regulation of exit from mitosis 3.8098E-3 6 4 1 6292
    cellular biosynthetic process 4.5365E-3 6 1567 5 6292
    cellular component organization 4.7462E-3 6 1582 5 6292
    biosynthetic process 5.0373E-3 6 1602 5 6292
    cellular protein metabolic process 9.4683E-3 6 1074 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein phosphatase type 2A regulator activity 1.9272E-9 6 4 3 6292
    phosphatase regulator activity 8.4748E-7 6 23 3 6292
    protein phosphatase regulator activity 8.4748E-7 6 23 3 6292
    protein serine/threonine phosphatase activity 1.2428E-6 6 26 3 6292
    phosphoprotein phosphatase activity 5.8633E-6 6 43 3 6292
    phosphatase activity 4.9568E-5 6 87 3 6292
    phosphoric ester hydrolase activity 7.986E-5 6 102 3 6292
    enzyme regulator activity 6.5226E-4 6 207 3 6292
    hydrolase activity, acting on ester bonds 2.7916E-3 6 341 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle