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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CDC36
  • nucleus
  • cytoplasm
  • CCR4-NOT core complex
    		•
  • negative regulation of transcription from RNA polymerase II promoter
  • response to pheromone involved in conjugation with cellular fusion
  • nuclear-transcribed mRNA poly(A) tail shortening
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • protein ubiquitination
    		•
  • ubiquitin-protein ligase activity
  • 3'-5'-exoribonuclease activity
    		•
    NOT5
  • cytoplasm
  • CCR4-NOT core complex
    		•
  • nuclear-transcribed mRNA poly(A) tail shortening
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • protein ubiquitination
    		•
  • ubiquitin-protein ligase activity
  • 3'-5'-exoribonuclease activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    CCR4-NOT core complex 1.4147E-6 2 8 2 6292
    CCR4-NOT complex 4.5979E-6 2 14 2 6292
    transcription factor complex 1.2556E-4 2 71 2 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    nuclear lumen 5.1728E-3 2 453 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear-transcribed mRNA poly(A) tail shortening 1.4147E-6 2 8 2 6292
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1.7735E-5 2 27 2 6292
    mRNA 3'-end processing 2.3495E-5 2 31 2 6292
    nuclear-transcribed mRNA catabolic process 3.552E-5 2 38 2 6292
    RNA elongation from RNA polymerase II promoter 3.744E-5 2 39 2 6292
    RNA 3'-end processing 4.3504E-5 2 42 2 6292
    RNA elongation 5.0022E-5 2 45 2 6292
    protein ubiquitination 1.051E-4 2 65 2 6292
    mRNA catabolic process 1.1854E-4 2 69 2 6292
    RNA catabolic process 1.5966E-4 2 80 2 6292
    protein modification by small protein conjugation 1.8468E-4 2 86 2 6292
    protein modification by small protein conjugation or removal 3.2544E-4 2 114 2 6292
    mRNA processing 6.1087E-4 2 156 2 6292
    mRNA metabolic process 1.1408E-3 2 213 2 6292
    regulation of transcription from RNA polymerase II promoter 1.3075E-3 2 228 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    post-translational protein modification 3.2108E-3 2 357 2 6292
    regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
    regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
    RNA processing 3.6384E-3 2 380 2 6292
    regulation of transcription 3.7155E-3 2 384 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    catabolic process 6.2027E-3 2 496 2 6292
    protein modification process 6.278E-3 2 499 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    transcription 7.6839E-3 2 552 2 6292
    macromolecule modification 8.1649E-3 2 569 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    3'-5'-exoribonuclease activity 1.2783E-5 2 23 2 6292
    exoribonuclease activity 1.6421E-5 2 26 2 6292
    exoribonuclease activity, producing 5'-phosphomonoesters 1.6421E-5 2 26 2 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.8346E-5 2 34 2 6292
    3'-5' exonuclease activity 3.0063E-5 2 35 2 6292
    exonuclease activity 5.2295E-5 2 46 2 6292
    ubiquitin-protein ligase activity 8.0641E-5 2 57 2 6292
    small conjugating protein ligase activity 9.5546E-5 2 62 2 6292
    acid-amino acid ligase activity 1.2556E-4 2 71 2 6292
    ligase activity, forming carbon-nitrogen bonds 2.2085E-4 2 94 2 6292
    ribonuclease activity 5.5711E-4 2 149 2 6292
    ligase activity 5.6464E-4 2 150 2 6292
    nuclease activity 9.9543E-4 2 199 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle