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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARX1
  • cytoplasm
  • nucleoplasm
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • DBP10
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • IPI3
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • MRT4
  • nucleus
  • nucleolus
  • ribosomal large subunit biogenesis
  • telomere maintenance
  • ribosome biogenesis
  • rRNA processing
  • mRNA catabolic process
  • molecular_function
  • NOG1
  • nuclear outer membrane
  • nucleolus
  • preribosome, large subunit precursor
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • GTP binding
  • NOG2
  • nucleus
  • nucleolus
  • nucleoplasm
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • GTPase activity
  • NOP15
  • nucleus
  • nucleolus
  • cytokinesis, actomyosin contractile ring assembly
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOP7
  • nucleus
  • nucleolus
  • cell proliferation
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • cell cycle
  • molecular_function
  • NSA2
  • nucleus
  • preribosome, large subunit precursor
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • molecular_function
  • NUG1
  • nucleus
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • GTPase activity
  • RIX1
  • nucleus
  • nuclear outer membrane
  • nucleoplasm
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • SDA1
  • nucleus
  • ribosome biogenesis
  • traversing start control point of mitotic cell cycle
  • ribosome assembly
  • actin cytoskeleton organization
  • molecular_function
  • TIF6
  • nucleus
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • ribosomal subunit export from nucleus
  • ribosomal large subunit biogenesis
  • processing of 27S pre-rRNA
  • ribosomal large subunit binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear lumen 1.0907E-13 15 453 13 6292
    nucleolus 3.7798E-12 15 211 10 6292
    organelle lumen 1.4368E-11 15 660 13 6292
    intracellular organelle lumen 1.4368E-11 15 660 13 6292
    membrane-enclosed lumen 3.0682E-11 15 700 13 6292
    nuclear part 1.0289E-8 15 1103 13 6292
    nucleus 4.4738E-8 15 2041 15 6292
    nuclear outer membrane 1.1443E-6 15 86 5 6292
    nuclear membrane 2.0866E-6 15 97 5 6292
    non-membrane-bounded organelle 9.3448E-6 15 959 10 6292
    intracellular non-membrane-bounded organelle 9.3448E-6 15 959 10 6292
    outer membrane 4.086E-5 15 178 5 6292
    organelle outer membrane 4.086E-5 15 178 5 6292
    nuclear envelope 6.9785E-5 15 199 5 6292
    organelle part 8.5313E-5 15 2282 13 6292
    intracellular organelle part 8.5313E-5 15 2282 13 6292
    nuclear membrane-endoplasmic reticulum network 1.4477E-4 15 232 5 6292
    preribosome, large subunit precursor 1.8916E-4 15 9 2 6292
    membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular organelle 1.4392E-3 15 4070 15 6292
    organelle 1.4445E-3 15 4071 15 6292
    endomembrane system 1.7459E-3 15 398 5 6292
    preribosome 2.8479E-3 15 34 2 6292
    nucleoplasm 2.866E-3 15 264 4 6292
    envelope 4.9781E-3 15 505 5 6292
    organelle envelope 4.9781E-3 15 505 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit biogenesis 2.2507E-22 15 65 12 6292
    ribosome biogenesis 9.5036E-20 15 346 15 6292
    ribonucleoprotein complex biogenesis 3.1258E-19 15 374 15 6292
    cellular component biogenesis 3.7988E-15 15 694 15 6292
    ribosome assembly 4.0637E-9 15 64 6 6292
    organelle assembly 6.4574E-9 15 69 6 6292
    ribonucleoprotein complex assembly 3.7332E-8 15 92 6 6292
    establishment of ribosome localization 3.0329E-7 15 26 4 6292
    ribosome localization 3.0329E-7 15 26 4 6292
    ribosomal subunit export from nucleus 3.0329E-7 15 26 4 6292
    cellular macromolecular complex assembly 2.1736E-6 15 182 6 6292
    processing of 27S pre-rRNA 6.027E-6 15 16 3 6292
    establishment of organelle localization 6.6428E-6 15 55 4 6292
    cellular macromolecular complex subunit organization 1.68E-5 15 259 6 6292
    macromolecular complex assembly 2.677E-5 15 281 6 6292
    organelle localization 3.7807E-5 15 85 4 6292
    nuclear export 8.0486E-5 15 103 4 6292
    macromolecular complex subunit organization 1.0337E-4 15 357 6 6292
    ribosomal large subunit assembly 1.1069E-4 15 41 3 6292
    cellular component assembly 1.5738E-4 15 385 6 6292
    nuclear transport 1.9905E-4 15 130 4 6292
    nucleocytoplasmic transport 1.9905E-4 15 130 4 6292
    ribosomal subunit assembly 2.67E-4 15 55 3 6292
    obsolete_biological_process 3.4578E-4 15 60 3 6292
    rRNA processing 3.1286E-3 15 128 3 6292
    rRNA metabolic process 3.7927E-3 15 137 3 6292
    cellular process 5.0732E-3 15 4426 15 6292
    actomyosin structure organization 7.136E-3 15 3 1 6292
    cytokinesis, actomyosin contractile ring assembly 7.136E-3 15 3 1 6292
    assembly of actomyosin apparatus involved in cell cycle cytokinesis 7.136E-3 15 3 1 6292
    organelle organization 9.8079E-3 15 1127 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal large subunit binding 2.384E-3 15 1 1 6292
    GTPase activity 8.9514E-3 15 61 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle