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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 1.9041E-24 15 72 13 6292
    ribonucleoprotein complex 6.9455E-15 15 514 14 6292
    nuclear outer membrane 5.0848E-14 15 86 9 6292
    nuclear membrane 1.5652E-13 15 97 9 6292
    outer membrane 4.1064E-11 15 178 9 6292
    organelle outer membrane 4.1064E-11 15 178 9 6292
    nuclear envelope 1.1243E-10 15 199 9 6292
    nucleolus 1.9043E-10 15 211 9 6292
    nuclear membrane-endoplasmic reticulum network 4.4607E-10 15 232 9 6292
    preribosome 9.7994E-9 15 34 5 6292
    endomembrane system 5.2838E-8 15 398 9 6292
    macromolecular complex 6.9919E-8 15 1635 14 6292
    nuclear lumen 1.6291E-7 15 453 9 6292
    envelope 4.1644E-7 15 505 9 6292
    organelle envelope 4.1644E-7 15 505 9 6292
    nuclear part 3.1469E-6 15 1103 11 6292
    organelle lumen 4.0779E-6 15 660 9 6292
    intracellular organelle lumen 4.0779E-6 15 660 9 6292
    membrane part 4.1832E-6 15 662 9 6292
    organelle membrane 6.0739E-6 15 692 9 6292
    membrane-enclosed lumen 6.689E-6 15 700 9 6292
    90S preribosome 7.3081E-6 15 17 3 6292
    non-membrane-bounded organelle 9.3448E-6 15 959 10 6292
    intracellular non-membrane-bounded organelle 9.3448E-6 15 959 10 6292
    small-subunit processome 7.9142E-5 15 6 2 6292
    membrane 5.2722E-4 15 1198 9 6292
    intracellular organelle part 6.8752E-4 15 2282 12 6292
    organelle part 6.8752E-4 15 2282 12 6292
    nucleus 1.3856E-3 15 2041 11 6292
    box C/D snoRNP complex 4.7627E-3 15 2 1 6292
    Noc4p-Nop14p complex 4.7627E-3 15 2 1 6292
    nucleolar part 4.9503E-3 15 45 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 6.2723E-23 15 59 12 6292
    rRNA processing 1.289E-18 15 128 12 6292
    rRNA metabolic process 3.0078E-18 15 137 12 6292
    ribosome biogenesis 2.5626E-17 15 346 14 6292
    ribonucleoprotein complex biogenesis 7.739E-17 15 374 14 6292
    ncRNA processing 7.7829E-16 15 215 12 6292
    ncRNA metabolic process 6.8437E-15 15 257 12 6292
    cellular component biogenesis 4.7289E-13 15 694 14 6292
    RNA processing 7.689E-13 15 380 12 6292
    RNA metabolic process 4.0505E-8 15 954 12 6292
    gene expression 6.9534E-8 15 1283 13 6292
    nucleic acid metabolic process 3.6766E-6 15 1415 12 6292
    rRNA modification 8.7571E-6 15 18 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.1456E-5 15 1566 12 6292
    cellular nitrogen compound metabolic process 4.4458E-5 15 1770 12 6292
    nitrogen compound metabolic process 5.0606E-5 15 1791 12 6292
    cellular macromolecule metabolic process 8.6671E-5 15 2285 13 6292
    macromolecule metabolic process 1.2073E-4 15 2349 13 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.0759E-4 15 13 2 6292
    RNA modification 5.4525E-4 15 70 3 6292
    primary metabolic process 1.4206E-3 15 2896 13 6292
    ribosomal small subunit biogenesis 1.6681E-3 15 26 2 6292
    cellular metabolic process 2.4151E-3 15 3033 13 6292
    metabolic process 3.8068E-3 15 3157 13 6292
    cellular process 5.0732E-3 15 4426 15 6292
    ncRNA 5'-end processing 7.136E-3 15 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.136E-3 15 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.136E-3 15 3 1 6292
    rRNA 5'-end processing 7.136E-3 15 3 1 6292
    RNA 5'-end processing 7.136E-3 15 3 1 6292
    maturation of 5.8S rRNA 9.5041E-3 15 4 1 6292
    cleavage involved in rRNA processing 9.5041E-3 15 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5041E-3 15 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5041E-3 15 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 9.5041E-3 15 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5041E-3 15 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 8.1807E-16 15 31 8 6292
    RNA binding 5.5714E-7 15 367 8 6292
    nucleic acid binding 4.9401E-5 15 666 8 6292
    binding 5.0296E-3 15 1294 8 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle