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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 23 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP15
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP8
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 1.4308E-37 23 72 20 6292
    nuclear outer membrane 1.9534E-21 23 86 14 6292
    nuclear membrane 1.1859E-20 23 97 14 6292
    ribonucleoprotein complex 1.7404E-19 23 514 20 6292
    outer membrane 8.2621E-17 23 178 14 6292
    organelle outer membrane 8.2621E-17 23 178 14 6292
    nuclear envelope 4.0481E-16 23 199 14 6292
    nucleolus 9.2875E-16 23 211 14 6292
    nuclear membrane-endoplasmic reticulum network 3.5471E-15 23 232 14 6292
    endomembrane system 6.3657E-12 23 398 14 6292
    nuclear lumen 3.7085E-11 23 453 14 6292
    envelope 1.6094E-10 23 505 14 6292
    organelle envelope 1.6094E-10 23 505 14 6292
    macromolecular complex 1.377E-9 23 1635 20 6292
    nuclear part 4.361E-9 23 1103 17 6292
    organelle lumen 5.6859E-9 23 660 14 6292
    intracellular organelle lumen 5.6859E-9 23 660 14 6292
    membrane part 5.917E-9 23 662 14 6292
    organelle membrane 1.0591E-8 23 692 14 6292
    membrane-enclosed lumen 1.2312E-8 23 700 14 6292
    preribosome 1.0647E-7 23 34 5 6292
    non-membrane-bounded organelle 7.0705E-7 23 959 14 6292
    intracellular non-membrane-bounded organelle 7.0705E-7 23 959 14 6292
    membrane 1.1142E-5 23 1198 14 6292
    Noc4p-Nop14p complex 1.2783E-5 23 2 2 6292
    nucleolar part 1.8311E-5 23 45 4 6292
    90S preribosome 2.8067E-5 23 17 3 6292
    nucleus 5.3624E-5 23 2041 17 6292
    Noc complex 1.2698E-4 23 5 2 6292
    small-subunit processome 1.9005E-4 23 6 2 6292
    preribosome, small subunit precursor 1.9005E-4 23 6 2 6292
    intracellular organelle part 2.6209E-4 23 2282 17 6292
    organelle part 2.6209E-4 23 2282 17 6292
    intracellular part 3.7561E-3 23 4938 23 6292
    intracellular 4.4613E-3 23 4975 23 6292
    box C/D snoRNP complex 7.2981E-3 23 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 2.5816E-31 23 59 17 6292
    ribosome biogenesis 5.241E-30 23 346 23 6292
    rRNA processing 1.5126E-29 23 128 19 6292
    ribonucleoprotein complex biogenesis 3.323E-29 23 374 23 6292
    rRNA metabolic process 6.0271E-29 23 137 19 6292
    ncRNA processing 4.9003E-25 23 215 19 6292
    ncRNA metabolic process 1.6248E-23 23 257 19 6292
    cellular component biogenesis 6.8635E-23 23 694 23 6292
    RNA processing 3.1736E-20 23 380 19 6292
    RNA metabolic process 1.1219E-12 23 954 19 6292
    gene expression 2.5782E-10 23 1283 19 6292
    nucleic acid metabolic process 1.5186E-9 23 1415 19 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.3806E-9 23 1566 19 6292
    cellular nitrogen compound metabolic process 8.2578E-8 23 1770 19 6292
    nitrogen compound metabolic process 1.0167E-7 23 1791 19 6292
    rRNA modification 4.0148E-7 23 18 4 6292
    cellular macromolecule metabolic process 6.9138E-6 23 2285 19 6292
    macromolecule metabolic process 1.1038E-5 23 2349 19 6292
    ribosomal small subunit biogenesis 1.0504E-4 23 26 3 6292
    RNA modification 1.0606E-4 23 70 4 6292
    cellular process 3.0112E-4 23 4426 23 6292
    primary metabolic process 3.4697E-4 23 2896 19 6292
    cellular metabolic process 7.2197E-4 23 3033 19 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.7297E-4 23 13 2 6292
    metabolic process 1.3484E-3 23 3157 19 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 1.2292E-28 23 31 14 6292
    RNA binding 2.0953E-12 23 367 14 6292
    nucleic acid binding 6.4051E-9 23 666 14 6292
    binding 4.2208E-6 23 1294 15 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle