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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.642504802816]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromatin 1.4784E-4 2 77 2 6292
chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
nuclear nucleosome 3.811E-3 2 12 1 6292
nucleosome 3.811E-3 2 12 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of histone methylation 3.1786E-4 2 1 1 6292
negative regulation of histone methylation 3.1786E-4 2 1 1 6292
negative regulation of histone modification 3.1786E-4 2 1 1 6292
regulation of histone modification 3.1786E-4 2 1 1 6292
negative regulation of histone H3-K36 methylation 3.1786E-4 2 1 1 6292
regulation of histone H3-K36 methylation 3.1786E-4 2 1 1 6292
protein peptidyl-prolyl isomerization 3.1786E-4 2 1 1 6292
histone peptidyl-prolyl isomerization 3.1786E-4 2 1 1 6292
histone H3-K36 methylation 3.1786E-4 2 1 1 6292
histone lysine methylation 6.3568E-4 2 2 1 6292
regulation of chromosome organization 6.3568E-4 2 2 1 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
negative regulation of protein modification process 1.2712E-3 2 4 1 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
regulation of protein modification process 2.224E-3 2 7 1 6292
regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
regulation of transcription 3.7155E-3 2 384 2 6292
negative regulation of DNA recombination 3.811E-3 2 12 1 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
negative regulation of cellular protein metabolic process 4.7627E-3 2 15 1 6292
regulation of DNA recombination 4.7627E-3 2 15 1 6292
regulation of gene expression 4.9915E-3 2 445 2 6292
negative regulation of protein metabolic process 5.0798E-3 2 16 1 6292
nucleosome assembly 5.0798E-3 2 16 1 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
chromatin silencing at rDNA 5.7138E-3 2 18 1 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
chromatin assembly 6.0308E-3 2 19 1 6292
histone methylation 6.3477E-3 2 20 1 6292
transcription, DNA-dependent 6.3792E-3 2 503 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
negative regulation of DNA metabolic process 6.6645E-3 2 21 1 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
protein amino acid alkylation 7.6148E-3 2 24 1 6292
protein amino acid methylation 7.6148E-3 2 24 1 6292
transcription 7.6839E-3 2 552 2 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
nucleosome organization 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292
regulation of DNA metabolic process 9.8303E-3 2 31 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

peptidyl-prolyl cis-trans isomerase activity 4.4455E-3 2 14 1 6292
cis-trans isomerase activity 4.4455E-3 2 14 1 6292
histone binding 4.4455E-3 2 14 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle