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Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. The modification of histones by addition of methyl groups. Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of a histone. The covalent alteration of one or more amino acid residues within a histone protein. Any process that modulates the frequency, rate or extent of the covalent alteration of a histone. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones. Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of histone methylation
Acc: GO:0031061
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
Synonyms:
  • down-regulation of histone methylation
  • down regulation of histone methylation
  • downregulation of histone methylation
  • inhibition of histone methylation
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031061 - negative regulation of histone methylation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle