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Protein Overview: FAA1

General Information:
Name(s) found: FAA1 / YOR317W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; accounts for most acyl-CoA synthetase activity; localized to lipid particles [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 700 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: lipid transport [IGILink to PubMed article][IPILink to PubMed article]
    lipid metabolic process [IGILink to PubMed article][IMPLink to PubMed article]
    N-terminal protein myristoylation [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: long-chain fatty acid-CoA ligase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAQYTVPVG KAANEHETAP RRNYQCREKP LVRPPNTKCS TVYEFVLECF QKNKNSNAMG  60
   61 WRDVKEIHEE SKSVMKKVDG KETSVEKKWM YYELSHYHYN SFDQLTDIMH EIGRGLVKIG 120
  121 LKPNDDDKLH LYAATSHKWM KMFLGAQSQG IPVVTAYDTL GEKGLIHSLV QTGSKAIFTD 180
  181 NSLLPSLIKP VQAAQDVKYI IHFDSISSED RRQSGKIYQS AHDAINRIKE VRPDIKTFSF 240
  241 DDILKLGKES CNEIDVHPPG KDDLCCIMYT SGSTGEPKGV VLKHSNVVAG VGGASLNVLK 300
  301 FVGNTDRVIC FLPLAHIFEL VFELLSFYWG ACIGYATVKT LTSSSVRNCQ GDLQEFKPTI 360
  361 MVGVAAVWET VRKGILNQID NLPFLTKKIF WTAYNTKLNM QRLHIPGGGA LGNLVFKKIR 420
  421 TATGGQLRYL LNGGSPISRD AQEFITNLIC PMLIGYGLTE TCASTTILDP ANFELGVAGD 480
  481 LTGCVTVKLV DVEELGYFAK NNQGEVWITG ANVTPEYYKN EEETSQALTS DGWFKTGDIG 540
  541 EWEANGHLKI IDRKKNLVKT MNGEYIALEK LESVYRSNEY VANICVYADQ SKTKPVGIIV 600
  601 PNHAPLTKLA KKLGIMEQKD SSINIENYLE DAKLIKAVYS DLLKTGKDQG LVGIELLAGI 660
  661 VFFDGEWTPQ NGFVTSAQKL KRKDILNAVK DKVDAVYSSS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) FAA1 NDE1
    View Details Ho Y, et al. (2002) ACC1 ADR1 ARP2 AYR1 BGL2 CBP6 CCT6 CDC60 CYR1 DBF2 DEF1 ENP1 FAA1 FAA4 GAR1 GCN3 GDE1 GLT1 GPH1 GSF2 GSP1 GUF1 HEF3 HEM15 HRP1 KAP104 KGD1 KTR3 MAE1 MDH1 MKT1 MOB1 MRT4 NAB2 NDE1 NPA3 OAC1 PET10 PET9 PRO2 PSD1 PTC6 PYC1 RAD1 RMT2 RNR2 RPN5 RPT3 RPT4 RPT5 SAP155 SAP185 SAP190 SEC27 SIT4 SLC1 TAP42 TFG2 TFP1 TIF1, TIF2 TPS1 VMA8 YDL063C YHM2 YMR196W YNL035C
    View Details Qiu et al. (2008) FAA1 FAT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIA40 No Comments Hazbun TR, et al. (2003)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data FAA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] deduced N/A No confident structure predictions are available.
    2 View Details [80..87]
    [101..266]    		 PSI-BLAST 238.741366 Luciferase
    3 View Details [88..100]
    [267..554]    		 PSI-BLAST 238.741366 Luciferase
    4 View Details [555..700] PSI-BLAST 238.741366 Luciferase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle