Bait Protein: | VAM3 |
Organism: | Saccharomyces cerevisiae |
Publication: | Hao Xu , Youngsoo Jun, James Thompson, John Yates and William Wickner (2010) HOPS Prevents the Disassembly of Trans-SNARE Complexes by Sec17p/Sec18p during Membrane Fusion [In Press] |
Comments: | Sample: HX11 - both fusion and trans-SNARE complex formation take place. |
Raw Data: |
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UNFILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
[ |
Contaminant_KERA... | 60 | 818 | 50.4% | 0.0955 | 65494 | |
[ |
KRT10 | keratin 10 | 57 | 764 | 49.6% | 0.0967 | 59519 |
[ |
KRT2 | keratin 2 | 52 | 581 | 51.3% | 0.0676 | 65865 |
[ |
gi|2119236, gi|4... | sp|P35527|K1CI_HUMAN Keratin, type I cytoskeletal 9 (Cytokeratin 9) (K9) (CK 9), gi|545257|gb|AAC60... | 43 | 270 | 60.8% | 0.0326 | 61987 |
[ |
KRT5 | keratin 5 | 42 | 285 | 54.2% | 0.0362 | 62461 |
[ |
contaminant_KERA... | 40 | 279 | 52.1% | 0.0373 | 59822 | |
[ |
gi|34069 | gi|34069|emb|CAA24760.1| unnamed protein product [Homo sapiens] | 34 | 268 | 66.7% | 0.0563 | 39219 |
[ |
contaminant_KERA... | 27 | 106 | 41.2% | 0.017 | 50499 | |
[ |
Contaminant_KERA... | 25 | 90 | 38.9% | 0.0143 | 51531 | |
[ |
SEC17 | Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' ste... | 24 | 247 | 66.8% | 0.0635 | 32803 |
[ |
VAM7 | Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; function... | 19 | 247 | 49.1% | 0.0587 | 36711 |
[ |
KRT17 | keratin 17 | 19 | 36 | 30.6% | 0.00627 | 47974 |
[ |
KRT3 | keratin 3 | 15 | 324 | 18.4% | 0.0387 | 64511 |
[ |
VAM3 | Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein tr... | 14 | 189 | 35.3% | 0.0501 | 32498 |
[ |
VAM6 | Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by fa... | 13 | 44 | 16.2% | 0.00315 | 122881 |
[ |
contaminant_KERA... | isb|A33652|A33652|probable keratin 16, type I, pseudogene - human | 13 | 46 | 15.6% | 0.0073 | 50915 |
[ |
PDA1 | E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarbo... | 12 | 46 | 27.6% | 0.00822 | 46343 |
[ |
SSA2 | ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shoc... | 12 | 46 | 25.4% | 0.0054 | 69470 |
[ |
KAR2 | ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding i... | 12 | 77 | 21.1% | 0.00847 | 74468 |
[ |
YPK9 | Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-t... | 12 | 41 | 11.9% | 0.00209 | 166749 |
[ |
KRT15 | keratin 15 | 11 | 28 | 13.2% | 0.00461 | 49168 |
[ |
NYV1 | v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent C... | 10 | 55 | 39.9% | 0.0163 | 28964 |
[ |
PHO8 | Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of in... | 10 | 39 | 18.9% | 0.00517 | 63004 |
[ |
YDR089W | Protein of unknown function; deletion confers resistance to Nickel | 10 | 43 | 13.5% | 0.00371 | 98712 |
[ |
KRT19 | keratin 19 | 10 | 23 | 13.5% | 0.00431 | 44106 |
[ |
KRT76 | keratin 76 | 10 | 71 | 9.4% | 0.00835 | 65871 |
[ |
SSB2 | Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partn... | 9 | 16 | 23.3% | 0.00196 | 66595 |
[ |
LAT1 | Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes... | 9 | 48 | 19.5% | 0.00747 | 51818 |
[ |
gi|34033, gi|71526 | pir||KRHU3 keratin 13, type I, cytoskeletal, long splice form - human, gi|34033|emb|CAA32786.1| ker... | 9 | 23 | 10.5% | 0.00377 | 49644 |
[ |
TFP1 | Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein prec... | 9 | 24 | 8.6% | 0.00168 | 118637 |
[ |
FKS1 | Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic sub... | 9 | 22 | 8.0% | 8.8E-4 | 214849 |
[ |
YCF1 | Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detox... | 9 | 31 | 7.9% | 0.00154 | 171120 |
[ |
URA2 | Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes t... | 9 | 14 | 5.7% | 4.75E-4 | 245123 |
[ |
contaminant_TRYP... | null | 8 | 15 | 17.0% | 0.00492 | 23993 |
[ |
SHM2 | Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrof... | 8 | 18 | 16.6% | 0.00288 | 52219 |
[ |
VPH1 | Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V... | 8 | 28 | 13.1% | 0.0025 | 95529 |
[ |
gi|105815 | pir||A34720 keratin 8, type II cytoskeletal - human | 8 | 28 | 9.3% | 0.00435 | 53748 |
[ |
VAC7 | Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p k... | 8 | 12 | 7.0% | 7.73E-4 | 128140 |
[ |
CDC19 | Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvat... | 7 | 16 | 22.0% | 0.0024 | 54545 |
[ |
PMA1 | Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plas... | 7 | 13 | 14.1% | 0.00106 | 99619 |
[ |
ADE5,7 | Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole... | 7 | 10 | 13.8% | 9.36E-4 | 86068 |
[ |
VTC3 | Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... | 7 | 21 | 11.0% | 0.00189 | 96553 |
[ |
VPS16 | Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; par... | 7 | 7 | 10.5% | 6.58E-4 | 92741 |
[ |
VPS41 | Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sort... | 7 | 21 | 8.3% | 0.00159 | 113412 |
[ |
Contaminant_KERA... | 7 | 76 | 7.5% | 0.0107 | 57265 | |
[ |
YBT1 | Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mam... | 7 | 14 | 5.4% | 6.33E-4 | 189161 |
[ |
VTI1 | Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and ... | 6 | 175 | 26.7% | 0.0605 | 24668 |
[ |
SSC1 | Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitoc... | 6 | 8 | 15.7% | 9.18E-4 | 70628 |
[ |
PPN1 | Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer | 6 | 12 | 13.6% | 0.00134 | 78344 |
[ |
CPS1 | Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions | 6 | 11 | 12.5% | 0.00143 | 64597 |
[ |
INT-STD1, Contam... | 1 | 6 | 17 | 10.9% | 0.0021 | 69271 |
[ |
VTC4 | Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) comp... | 6 | 17 | 10.8% | 0.00177 | 83155 |
[ |
SPA_STAAU | Immunoglobulin G-binding protein A OS=Staphylococcus aureus GN=spa PE=1 SV=1 | 6 | 12 | 10.6% | 0.00177 | 55439 |
[ |
HMG1 | One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, whi... | 6 | 22 | 8.4% | 0.00157 | 115625 |
[ |
PEP5 | Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein tra... | 6 | 16 | 6.2% | 0.00117 | 117477 |
[ |
PDB1 | E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved mu... | 5 | 60 | 18.9% | 0.0123 | 40054 |
[ |
IVY1 | Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the... | 5 | 6 | 16.8% | 9.94E-4 | 49976 |
[ |
DBP2 | Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated m... | 5 | 10 | 11.4% | 0.00137 | 60999 |
[ |
SEC18 | ATPase required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuol... | 5 | 10 | 11.2% | 9.9E-4 | 84056 |
[ |
DAP2 | Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membra... | 5 | 20 | 9.5% | 0.00183 | 93404 |
[ |
YME1 | Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible f... | 5 | 11 | 7.9% | 0.00111 | 81772 |
[ |
PEP3 | Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular ... | 5 | 6 | 6.3% | 4.9E-4 | 107398 |
[ |
YER138C | Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is proces... | 5 | 9 | 3.9% | 3.85E-4 | 198561 |
[ |
TDH3 | Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tet... | 4 | 9 | 18.1% | 0.00203 | 35747 |
[ |
TDH2 | Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tet... | 4 | 9 | 18.1% | 0.00203 | 35847 |
[ |
RPL8A | Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has simila... | 4 | 7 | 18.0% | 0.00205 | 28125 |
[ |
RPL8B | Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has simila... | 4 | 7 | 18.0% | 0.00205 | 28112 |
[ |
PSA1 | GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from ... | 4 | 12 | 15.8% | 0.00249 | 39566 |
[ |
PDX1 | Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogena... | 4 | 5 | 13.4% | 9.15E-4 | 45362 |
[ |
contaminant_NRL_... | owl|| Immunoglobulin g1 (igg1) (mcg) with a hinge deletion, chain H... | 4 | 6 | 11.4% | 0.00105 | 46852 |
[ |
PHO84 | High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated... | 4 | 27 | 10.1% | 0.00345 | 64382 |
[ |
GRP78_RAT | 78 kDa glucose-regulated protein OS=Rattus norvegicus GN=Hspa5 PE=1 SV=1 | 4 | 5 | 9.3% | 5.74E-4 | 72347 |
[ |
gi|1143492, gi|8... | pir||A29821 dnaK-type molecular chaperone HSPA5 precursor - human, gi|386758|gb|AAA52614.1| GRP78 p... | 4 | 5 | 9.3% | 5.75E-4 | 72116 |
[ |
gi|109893 | pir||A37048 dnaK-type molecular chaperone grp78 precursor - mouse | 4 | 5 | 9.3% | 5.73E-4 | 72421 |
[ |
GRP78_MESAU | 78 kDa glucose-regulated protein OS=Mesocricetus auratus GN=HSPA5 PE=1 SV=1 | 4 | 5 | 9.3% | 5.74E-4 | 72379 |
[ |
VAC8 | Phosphorylated and palmitoylated vacuolar membrane protein that interacts with Atg13p, required for ... | 4 | 14 | 9.2% | 0.00182 | 63208 |
[ |
SEC63 | Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/Bi... | 4 | 5 | 8.3% | 5.66E-4 | 75345 |
[ |
FRA1 | Protein involved in negative regulation of transcription of iron regulon; forms an iron independent ... | 4 | 20 | 7.2% | 0.002 | 84924 |
[ |
MNN1 | Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for add... | 4 | 9 | 6.0% | 8.86E-4 | 88529 |
[ |
MNR2 | Vacuolar membrane protein required for magnesium homeostasis; putative magnesium transporter; has si... | 4 | 8 | 5.8% | 6.2E-4 | 109736 |
[ |
CHS1 | Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-ac... | 4 | 6 | 5.7% | 3.98E-4 | 129919 |
[ |
PHO91 | Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90,... | 4 | 11 | 3.2% | 9.23E-4 | 99490 |
[ |
RPL19B, RPL19A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Ap and has similari... | 3 | 3 | 19.0% | 0.00119 | 21704 |
[ |
SEC4 | Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with t... | 3 | 7 | 17.2% | 0.00244 | 23506 |
[ |
VMA6 | Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an elect... | 3 | 4 | 14.8% | 8.7E-4 | 39791 |
[ |
CCC1 | Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack ... | 3 | 3 | 11.2% | 6.99E-4 | 34250 |
[ |
NOP56 | Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that ... | 3 | 6 | 10.5% | 8.93E-4 | 56864 |
[ |
PDI1 | Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, es... | 3 | 9 | 10.2% | 0.00129 | 58227 |
[ |
RPL13A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential f... | 3 | 3 | 9.0% | 0.00113 | 22554 |
[ |
RPL13B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential f... | 3 | 3 | 9.0% | 0.00113 | 22525 |
[ |
VMA2 | Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), a... | 3 | 3 | 8.9% | 4.35E-4 | 57749 |
[ |
LPD1 | Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydroge... | 3 | 7 | 8.4% | 0.00105 | 54010 |
[ |
LCB4 | Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which fun... | 3 | 4 | 7.9% | 4.81E-4 | 69639 |
[ |
DED1 | ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all ye... | 3 | 3 | 7.8% | 3.73E-4 | 65553 |
[ |
RMD8 | Cytosolic protein required for sporulation | 3 | 5 | 6.8% | 5.67E-4 | 75914 |
[ |
SAC1 | Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmemb... | 3 | 5 | 6.7% | 6.02E-4 | 71125 |
[ |
PHO90 | Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthet... | 3 | 7 | 5.0% | 5.96E-4 | 97689 |
[ |
VTC2 | Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuol... | 3 | 3 | 4.7% | 2.72E-4 | 95441 |
[ |
MAM3 | Protein required for normal mitochondrial morphology, has similarity to hemolysins | 3 | 3 | 4.5% | 3.19E-4 | 77712 |
[ |
PEP1 | Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golg... | 3 | 3 | 2.7% | 1.43E-4 | 177777 |
[ |
RPP2B | Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction ... | 2 | 3 | 28.2% | 0.00205 | 11050 |
[ |
RPP2A | Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction... | 2 | 2 | 23.6% | 0.00142 | 10746 |
[ |
RPL36A | N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to ... | 2 | 2 | 21.0% | 0.0015 | 11124 |
[ |
RPL36B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similari... | 2 | 2 | 21.0% | 0.0015 | 11135 |
[ |
RPL12B, RPL12A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b d... | 2 | 4 | 20.6% | 0.00182 | 17823 |
[ |
RPS17B | Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similari... | 2 | 9 | 19.1% | 0.00497 | 15803 |
[ |
RPS17A | Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similari... | 2 | 9 | 19.1% | 0.00497 | 15788 |
[ |
RPS16B, RPS16A | Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E... | 2 | 7 | 18.9% | 0.00367 | 15847 |
[ |
RPL25 | Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarit... | 2 | 2 | 18.3% | 0.00106 | 15758 |
[ |
RPL9A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarit... | 2 | 5 | 16.2% | 0.00196 | 21569 |
[ |
RPL28 | Ribosomal protein of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a r... | 2 | 2 | 16.1% | 0.00101 | 16722 |
[ |
RPL17B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similari... | 2 | 11 | 15.8% | 0.00449 | 20551 |
[ |
RPL17A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similari... | 2 | 11 | 15.8% | 0.00449 | 20549 |
[ |
RPS13 | Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ri... | 2 | 5 | 14.6% | 0.00248 | 17029 |
[ |
RPL26A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similari... | 2 | 2 | 13.4% | 0.00118 | 14234 |
[ |
RPL26B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similari... | 2 | 2 | 13.2% | 0.00116 | 14609 |
[ |
RPS8B, RPS8A | Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to ra... | 2 | 3 | 12.5% | 0.00113 | 22490 |
[ |
TSA1 | Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-as... | 2 | 2 | 12.2% | 7.66E-4 | 21590 |
[ |
YKT6 | Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and wit... | 2 | 9 | 12.0% | 0.00338 | 22707 |
[ |
YNL058C | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 8 | 11.4% | 0.0019 | 35046 |
[ |
RPL7A | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarit... | 2 | 5 | 11.1% | 0.00154 | 27638 |
[ |
RPL7B | Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarit... | 2 | 5 | 11.1% | 0.00154 | 27696 |
[ |
RPP0 | Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphoryl... | 2 | 8 | 8.7% | 0.00192 | 33717 |
[ |
YNL217W | Hypothetical protein | 2 | 4 | 8.3% | 9.21E-4 | 37151 |
[ |
SED5 | cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, bi... | 2 | 2 | 8.2% | 4.41E-4 | 38807 |
[ |
TUB1 | Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form... | 2 | 3 | 8.1% | 5.04E-4 | 49800 |
[ |
PGK1 | 3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phospha... | 2 | 3 | 7.7% | 5.41E-4 | 44738 |
[ |
YDL180W | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th... | 2 | 3 | 7.1% | 4.12E-4 | 62288 |
[ |
KTR1 | Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane pr... | 2 | 4 | 6.9% | 7.64E-4 | 46022 |
[ |
KTR6 | Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein... | 2 | 2 | 6.5% | 3.37E-4 | 52128 |
[ |
YCK3 | Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fus... | 2 | 2 | 5.9% | 2.86E-4 | 60261 |
[ |
TUB2 | Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymeriz... | 2 | 2 | 5.9% | 3.28E-4 | 50923 |
[ |
TDA7 | Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p | 2 | 3 | 5.7% | 3.54E-4 | 67357 |
[ |
PCL8 | Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen s... | 2 | 3 | 5.5% | 4.58E-4 | 55431 |
[ |
STD1 | Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1... | 2 | 2 | 5.4% | 3.38E-4 | 50261 |
[ |
MPS3 | Nuclear envelope protein required for SPB duplication and nuclear fusion; localizes to the SPB half ... | 2 | 2 | 5.1% | 2.2E-4 | 79175 |
[ |
HSP60 | Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides... | 2 | 2 | 4.9% | 2.62E-4 | 60752 |
[ |
SKG6 | Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell ... | 2 | 2 | 4.8% | 2.04E-4 | 81849 |
[ |
FAA1 | Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16... | 2 | 2 | 4.7% | 2.14E-4 | 77866 |
[ |
TAF7 | TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation | 2 | 2 | 4.4% | 2.54E-4 | 67556 |
[ |
RPL2A, RPL2B | Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E.... | 2 | 5 | 4.3% | 0.00148 | 27408 |
[ |
PYK2 | Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by ... | 2 | 2 | 4.2% | 2.97E-4 | 55195 |
[ |
DBP1 | Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability o... | 2 | 2 | 4.1% | 2.43E-4 | 67917 |
[ |
TEF1, TEF2 | Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction ... | 2 | 7 | 4.1% | 0.00115 | 50033 |
[ |
CHS2 | Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of ... | 2 | 2 | 3.8% | 1.56E-4 | 109882 |
[ |
SYG1 | Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G... | 2 | 2 | 3.5% | 1.66E-4 | 104217 |
[ |
VBA4 | Protein of unknown function with proposed role as a basic amino acid permease based on phylogeny; GF... | 2 | 2 | 3.4% | 1.95E-4 | 85683 |
[ |
Reverse_YML029W | USA1 SGDID:S000004491, Chr XIII from 217362-219878, Verified ORF, "Protein that interacts in the two... | 2 | 2 | 3.3% | 1.79E-4 | 96653 |
[ |
KRE6 | Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functional... | 2 | 2 | 3.3% | 2.08E-4 | 80123 |
[ |
CYK3 | SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype a... | 2 | 2 | 3.1% | 1.7E-4 | 100621 |
[ |
VPS33 | ATP-binding protein that is a subunit of the HOPS complex and of the CORVET tethering complex; essen... | 2 | 2 | 3.0% | 2.17E-4 | 79271 |
[ |
HMG2 | One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in... | 2 | 3 | 2.8% | 2.15E-4 | 115692 |
[ |
YLR241W | Putative protein of unknown function, may be involved in detoxification | 2 | 6 | 2.8% | 5.76E-4 | 89344 |
[ |
ENA1 | P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance | 2 | 2 | 2.7% | 1.38E-4 | 120357 |
[ |
ENA2 | P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li... | 2 | 2 | 2.7% | 1.38E-4 | 120317 |
[ |
ENA5 | Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family | 2 | 2 | 2.7% | 1.38E-4 | 120296 |
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PDR5 | Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by ... | 2 | 2 | 2.4% | 9.93E-5 | 170437 |
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YGR125W | Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal ... | 2 | 2 | 2.4% | 1.45E-4 | 116971 |
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MIS1 | Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation ... | 2 | 2 | 2.4% | 1.54E-4 | 106217 |
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PMC1 | Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activ... | 2 | 2 | 2.2% | 1.28E-4 | 130861 |
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RTC1 | Protein of unknown function; may interact with ribosomes, based on co-purification experiments; null... | 2 | 2 | 2.1% | 1.12E-4 | 149269 |
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Reverse_YOR326W | MYO2 SGDID:S000005853, Chr XV from 925716-930440, Verified ORF, "One of two type V myosins, involved... | 2 | 2 | 2.0% | 9.53E-5 | 180679 |
[ |
MHP1 | Microtubule-associated protein involved in assembly and stabilization of microtubules; overproductio... | 2 | 4 | 2.0% | 2.15E-4 | 155207 |
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SNF2 | Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation... | 2 | 4 | 1.9% | 1.76E-4 | 194050 |
[ |
BPT1 | ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the t... | 2 | 7 | 1.9% | 3.37E-4 | 176873 |
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RTG2 | Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcri... | 2 | 3 | 1.5% | 3.83E-4 | 65572 |
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Reverse_YOR290C | SNF2 SGDID:S000005816, Chr XV from 860255-855144, reverse complement, Verified ORF, "Catalytic subun... | 2 | 3 | 1.4% | 1.32E-4 | 194050 |
[ |
Reverse_YDL140C | RPO21 SGDID:S000002299, Chr IV from 210562-205361, reverse complement, Verified ORF, "RNA polymerase... | 2 | 2 | 1.3% | 8.66E-5 | 191610 |
[ |
Reverse_YDR283C | GCN2 SGDID:S000002691, Chr IV from 1030043-1025064, reverse complement, Verified ORF, "Protein kinas... | 2 | 3 | 1.3% | 1.36E-4 | 190192 |
[ |
Reverse_YPL084W | BRO1 SGDID:S000006005, Chr XVI from 394035-396569, Verified ORF, "Cytoplasmic class E vacuolar prote... | 2 | 4 | 1.3% | 3.55E-4 | 97276 |
[ |
GCN1 | Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate ... | 2 | 2 | 0.8% | 5.62E-5 | 296697 |
[ |
Reverse_YDR457W | TOM1 SGDID:S000002865, Chr IV from 1369780-1379586, Verified ORF, "E3 ubiquitin ligase of the hect-d... | 2 | 4 | 0.7% | 9.18E-5 | 374185 |