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View Protein Complex Details

Complex Overview

From Publication: Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65
Notes: Complex description from publication: 08. YGR002C Histone acetylation
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP4
  • nucleus
  • nuclear chromatin
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • DNA repair
  • chromatin remodeling
  • regulation of transcription, DNA-dependent
  • histone acetylation
  • chromatin organization
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • chromatin binding
  • EAF1
  • NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • molecular_function
  • EAF5
  • nucleus
  • NuA4 histone acetyltransferase complex
  • DNA repair
  • molecular_function
  • EPL1
  • NuA4 histone acetyltransferase complex
  • Piccolo NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • ESA1
  • NuA4 histone acetyltransferase complex
  • Piccolo NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • DNA repair
  • RNA elongation
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • RVB1
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • chromatin remodeling complex
  • chromatin remodeling
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • RVB2
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • nuclear outer membrane
  • chromatin remodeling complex
  • chromatin remodeling
  • snoRNA metabolic process
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • SWC4
  • nucleus
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • histone acetylation
  • DNA binding
  • SWR1
  • nucleus
  • Swr1 complex
  • chromatin remodeling
  • histone exchange
  • structural molecule activity
  • TRA1
  • NuA4 histone acetyltransferase complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • histone acetyltransferase complex
  • DNA repair
  • histone acetylation
  • regulation of transcription from RNA polymerase II promoter
  • histone acetyltransferase activity
  • YAF9
  • nucleus
  • NuA4 histone acetyltransferase complex
  • cytoplasm
  • Swr1 complex
  • DNA repair
  • chromatin remodeling
  • histone exchange
  • chromatin silencing at telomere
  • molecular_function
  • YNG2
  • nucleus
  • NuA4 histone acetyltransferase complex
  • Piccolo NuA4 histone acetyltransferase complex
  • histone acetyltransferase complex
  • chromatin modification
  • DNA repair
  • histone acetylation
  • enzyme activator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    H4/H2A histone acetyltransferase complex 1.0378E-23 12 14 9 6292
    NuA4 histone acetyltransferase complex 1.0378E-23 12 14 9 6292
    histone acetyltransferase complex 3.6277E-18 12 44 9 6292
    Swr1 complex 5.3396E-14 12 15 6 6292
    nucleoplasm part 3.5395E-11 12 245 9 6292
    nucleoplasm 6.9488E-11 12 264 9 6292
    nuclear part 8.0153E-10 12 1103 12 6292
    protein complex 1.1559E-9 12 1137 12 6292
    nuclear chromatin 1.7315E-9 12 73 6 6292
    chromatin 2.4037E-9 12 77 6 6292
    Piccolo NuA4 histone acetyltransferase complex 5.3017E-9 12 3 3 6292
    nuclear lumen 8.7176E-9 12 453 9 6292
    chromatin remodeling complex 1.1155E-8 12 99 6 6292
    macromolecular complex 9.1989E-8 12 1635 12 6292
    organelle lumen 2.4016E-7 12 660 9 6292
    intracellular organelle lumen 2.4016E-7 12 660 9 6292
    membrane-enclosed lumen 4.0143E-7 12 700 9 6292
    nuclear chromosome part 5.5684E-7 12 190 6 6292
    DNA helicase complex 8.673E-7 12 11 3 6292
    Ino80 complex 8.673E-7 12 11 3 6292
    nucleus 1.3278E-6 12 2041 12 6292
    nuclear chromosome 1.6322E-6 12 228 6 6292
    chromosomal part 2.0487E-6 12 237 6 6292
    chromosome 4.783E-6 12 274 6 6292
    intracellular organelle part 5.0851E-6 12 2282 12 6292
    organelle part 5.0851E-6 12 2282 12 6292
    membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    intracellular non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    intracellular organelle 5.3355E-3 12 4070 12 6292
    organelle 5.3513E-3 12 4071 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin modification 4.163E-17 12 168 11 6292
    chromatin organization 3.521E-16 12 203 11 6292
    DNA repair 3.8749E-12 12 192 9 6292
    histone acetylation 2.0425E-11 12 36 6 6292
    response to DNA damage stimulus 2.5229E-11 12 236 9 6292
    chromosome organization 2.5368E-11 12 555 11 6292
    protein amino acid acetylation 9.742E-11 12 46 6 6292
    cellular response to stress 1.6197E-10 12 290 9 6292
    protein amino acid acylation 4.6363E-10 12 59 6 6292
    chromatin remodeling 1.1179E-9 12 68 6 6292
    cellular response to stimulus 1.7827E-9 12 379 9 6292
    covalent chromatin modification 5.4445E-9 12 88 6 6292
    histone modification 5.4445E-9 12 88 6 6292
    response to stress 1.9816E-8 12 497 9 6292
    organelle organization 5.8749E-8 12 1127 11 6292
    DNA metabolic process 8.3417E-8 12 585 9 6292
    histone exchange 6.3144E-7 12 10 3 6292
    nucleic acid metabolic process 6.8885E-7 12 1415 11 6292
    response to stimulus 8.7905E-7 12 766 9 6292
    regulation of transcription, DNA-dependent 1.1261E-6 12 358 7 6292
    regulation of RNA metabolic process 1.2374E-6 12 363 7 6292
    regulation of transcription from RNA polymerase II promoter 1.6322E-6 12 228 6 6292
    regulation of transcription 1.8122E-6 12 384 7 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.0509E-6 12 1566 11 6292
    cellular component organization 2.2874E-6 12 1582 11 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.0629E-6 12 415 7 6292
    regulation of nitrogen compound metabolic process 3.113E-6 12 416 7 6292
    regulation of gene expression 4.9002E-6 12 445 7 6292
    regulation of macromolecule biosynthetic process 5.7732E-6 12 456 7 6292
    regulation of cellular biosynthetic process 7.2744E-6 12 472 7 6292
    regulation of biosynthetic process 7.3782E-6 12 473 7 6292
    cellular nitrogen compound metabolic process 7.6146E-6 12 1770 11 6292
    nitrogen compound metabolic process 8.6368E-6 12 1791 11 6292
    regulation of macromolecule metabolic process 9.0913E-6 12 488 7 6292
    transcription, DNA-dependent 1.1127E-5 12 503 7 6292
    RNA biosynthetic process 1.1885E-5 12 508 7 6292
    regulation of primary metabolic process 1.2852E-5 12 514 7 6292
    ATP-dependent chromatin remodeling 1.3448E-5 12 26 3 6292
    transcription from RNA polymerase II promoter 1.5323E-5 12 335 6 6292
    regulation of cellular metabolic process 1.6982E-5 12 536 7 6292
    nucleosome organization 1.8839E-5 12 29 3 6292
    regulation of metabolic process 1.9432E-5 12 547 7 6292
    transcription 2.064E-5 12 552 7 6292
    post-translational protein modification 2.2087E-5 12 357 6 6292
    cellular macromolecule metabolic process 1.144E-4 12 2285 11 6292
    protein modification process 1.475E-4 12 499 6 6292
    macromolecule metabolic process 1.5296E-4 12 2349 11 6292
    regulation of cellular process 2.2484E-4 12 796 7 6292
    regulation of biological process 2.805E-4 12 824 7 6292
    macromolecule modification 3.0613E-4 12 569 6 6292
    RNA metabolic process 7.0867E-4 12 954 7 6292
    primary metabolic process 1.3504E-3 12 2896 11 6292
    cellular metabolic process 2.1697E-3 12 3033 11 6292
    cellular macromolecule biosynthetic process 2.723E-3 12 1187 7 6292
    macromolecule biosynthetic process 2.7509E-3 12 1189 7 6292
    biological regulation 3.1032E-3 12 1213 7 6292
    metabolic process 3.2647E-3 12 3157 11 6292
    gene expression 4.3413E-3 12 1283 7 6292
    cellular protein metabolic process 8.8666E-3 12 1074 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetyltransferase activity 1.782E-8 12 17 4 6292
    lysine N-acetyltransferase activity 1.782E-8 12 17 4 6292
    ATP-dependent 5'-3' DNA helicase activity 1.8476E-7 12 7 3 6292
    5'-3' DNA helicase activity 2.953E-7 12 8 3 6292
    N-acetyltransferase activity 3.0142E-7 12 33 4 6292
    N-acyltransferase activity 5.4096E-7 12 38 4 6292
    acetyltransferase activity 1.6672E-6 12 50 4 6292
    ATP-dependent DNA helicase activity 4.257E-6 12 18 3 6292
    transferase activity, transferring acyl groups other than amino-acyl groups 1.9376E-5 12 92 4 6292
    acyltransferase activity 1.9376E-5 12 92 4 6292
    DNA helicase activity 3.0686E-5 12 34 3 6292
    transferase activity, transferring acyl groups 3.5238E-5 12 107 4 6292
    ATP-dependent helicase activity 8.7367E-5 12 48 3 6292
    purine NTP-dependent helicase activity 8.7367E-5 12 48 3 6292
    DNA-dependent ATPase activity 1.3153E-4 12 55 3 6292
    helicase activity 4.4694E-4 12 83 3 6292
    ATPase activity, coupled 2.4472E-3 12 149 3 6292
    ATPase activity 6.5368E-3 12 211 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle