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Protein Overview: KAO2_ARATH

General Information:
Name(s) found: KAO2_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Ent-kaurenoic acid oxidase 2 OS=Arabidopsis thaliana GN=KAO2 PE=2 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    Biological Process: gibberellin biosynthetic process [ISS][TAS]
    Molecular Function: oxygen binding [ISS]
    ent-kaurenoate oxidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETGLILMW FPLIILGLFV LKWVLKRVNV WIYVSKLGEK KHYLPPGDLG WPVIGNMWSF  60
   61 LRAFKTSDPE SFIQSYITRY GRTGIYKAHM FGYPCVLVTT PETCRRVLTD DDAFHIGWPK 120
  121 STMKLIGRKS FVGISFEEHK RLRRLTSAPV NGPEALSVYI QFIEETVNTD LEKWSKMGEI 180
  181 EFLSHLRKLT FKVIMYIFLS SESEHVMDSL EREYTNLNYG VRAMGINLPG FAYHRALKAR 240
  241 KKLVAAFQSI VTNRRNQRKQ NISSNRKDML DNLIDVKDEN GRVLDDEEII DLLLMYLNAG 300
  301 HESSGHLTMW ATILMQEHPM ILQKAKEEQE RIVKKRAPGQ KLTLKETREM VYLSQVIDET 360
  361 LRVITFSLTA FREAKSDVQM DGYIIPKGWK VLTWFRNVHL DPEIYPDPKK FDPSRWEGYT 420
  421 PKAGTFLPFG LGSHLCPGND LAKLEISIFL HHFLLKYRVE RSNPGCPVMF LPHNRPKDNC 480
  481 LARITRTMP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..489] PSI-BLAST 93.39794 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • retinoic acid binding
    		•  3.04897926497756 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • demethylase activity
    		•  2.17116413461366 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  1.71732865382274 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  1.71233606135238 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  1.68985995159863 bayes_pls_golite062009
  • oxygen binding
    		•  1.66120675703571 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  1.65569090470706 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  1.20113920678403 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  0.918503562996019 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.658520486133281 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  0.0888154993183798 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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