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Protein Overview: C71BE_ARATH

General Information:
Name(s) found: C71BE_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|15238726|ref|NP_197900.1| CYP71B14; electron carrier/ heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [NCBI NR]
  • gi|13878372|sp|P58051.1|C71BE_ARATH RecName: Full=Cytochrome P450 71B14 [NCBI NR]
  • (P58051) Cytochrome P450 71B14 (EC 1.14.-.-) [Swiss-Prot]
  • Cytochrome P450 71B14 OS=Arabidopsis thaliana GN=CYP71B14 PE=2 SV=1 [Swiss-Prot]
  • Cytochrome P450 71B14gi|15238726|ref|NP_197900.1| cytochrome P450 71B14, putative (CYP71B14) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cytochrome P450 71B14 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: CYP71B14 | CYP71B14 (cytochrome P450, family 71, subfamily B, polypeptide 14); oxygen binding | chr5:8694633-8696224 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Cytochrome P450 71B14 [nr-271106-contam.fasta]
  • CYP71B14; heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: CYP71B14 | cytochrome P450, family 71, subfamily B, polypeptide 14 | chr5:8694630-8696221 REVERSE LENGTH=496 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: oxygen binding [ISS]
    iron ion binding [IEA]
    electron carrier activity [IEA]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIWWFIVGAS FFFAFILIAK DTRTTKKNLP PGPPRLPIIG NLHQLGSKPQ RSLFKLSEKY  60
   61 GSLMSLKFGN VSAVVASTPE TVKDVLKTFD AECCSRPYMT YPARVTYNFN DLAFSPYSKY 120
  121 WREVRKMTVI ELYTAKRVKS FQNVRQEEVA SFVDFIKQHA SLEKTVNMKQ KLVKLSGSVI 180
  181 CKVGFGISLE WSKLANTYEE VIQGTMEVVG RFAAADYFPI IGRIIDRITG LHSKCEKVFK 240
  241 EMDSFFDQSI KHHLEDTNIK DDIIGLLLKM EKGETGLGEF QLTRNHTKGI LLNVLIAGVD 300
  301 TSGHTVTWVM THLIKNPRVM KKAQAEVREV IKNKDDITEE DIERLEYLKM VIKETLRINP 360
  361 LVPLLIPREA SKYIKIGGYD IPKKTWIYVN IWAVQRNPNV WKDPEVFIPE RFMHSEIDYK 420
  421 GVDFELLPFG SGRRMCPGMG LGMALVHLTL INLLYRFDWK LPEGMNIEDV DLEESYGLVC 480
  481 PKKVPLQLIP VLTQWT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..496] PSI-BLAST 112.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • electron carrier activity
    		•  4.64931978461551 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxygen binding
    		•  3.7203678182299 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  3.16634614522939 bayes_pls_golite062009
  • demethylase activity
    		•  2.80780658333504 bayes_pls_golite062009
  • retinoic acid binding
    		•  2.70323898361882 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • thromboxane-A synthase activity
    		•  2.45281910634006 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.33937429425924 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  2.30416050662077 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  0.918503562996019 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • protein binding
    		•  0.836411857417911 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • iron ion binding
    		•  0.529598228513719 bayes_pls_golite062009
  • cation binding
    		•  0.510556740388808 bayes_pls_golite062009
  • metal ion binding
    		•  0.510556740388808 bayes_pls_golite062009
  • ion binding
    		•  0.503326724714616 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.450436868179747 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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