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Protein Overview: C71AF_ARATH

General Information:
Name(s) found: C71AF_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|15238652|ref|NP_197877.1| CYP71A15; electron carrier/ heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [NCBI NR]
  • gi|13878367|sp|P58046.1|C71AF_ARATH RecName: Full=Cytochrome P450 71A15 [NCBI NR]
  • (P58046) Cytochrome P450 71A15 (EC 1.14.-.-) [Swiss-Prot]
  • Cytochrome P450 71A15 OS=Arabidopsis thaliana GN=CYP71A15 PE=3 SV=1 [Swiss-Prot]
  • Cytochrome P450 71A15gi|15238652|ref|NP_197877.1| cytochrome P450 71A15, putative (CYP71A15) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Cytochrome P450 71A15 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: CYP71A15 | CYP71A15 (cytochrome P450, family 71, subfamily A, polypeptide 15); oxygen binding | chr5:8595212-8597764 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Cytochrome P450 71A15 [nr-271106-contam.fasta]
  • CYP71A15; heme binding / iron ion binding / monooxygenase/ oxygen binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: CYP71A15 | cytochrome P450, family 71, subfamily A, polypeptide 15 | chr5:8595209-8597761 REVERSE LENGTH=496 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: biological_process [ND]
    Molecular Function: oxygen binding [ISS]
    iron ion binding [IEA]
    electron carrier activity [IEA]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIIIISLCL ATILAFLLLK PLLNRTVAKD NLPPSPWRVP VIGNLHQLSL HPHRSLRSLS  60
   61 HRYGPLMLLH FGRVPILVVS SSDVAHDLMK THDLKVANRP RLKVIETILN GGREVVFSPY 120
  121 GDYWRQIKTV CVVHLLNKKM VQSFAKVREE ERSVMMEKVE KASSDSSPLN LSKLLITLTS 180
  181 DVASRVSFGK KHSNEASMSD FKNQVRKITE LVGGFPVSEY IPCLAWIDQI RGLYNRAEEV 240
  241 SKIFGDLMDK VVQEHLDATN KPTKDFVDIL LSFERQSKDG IEVRRSDIKF IILDIFLGGT 300
  301 TTTNSLLEWT MTELIRHPEC MKKLQDEIRG DATNLTIYRS HEEVEDMKYL KAVIKEGLRL 360
  361 HPPFPLLVLR LLTQDVKLKG YDIAAGTQVI TNAWAIQRDI VTWGIDAEEF RPERHLDSPL 420
  421 DFRGTNFEYI PFGSGRRICP GIGFAMALVE VTLANLVNRF NWRMDARLSG DEYDLAEATG 480
  481 IDVCRKFPLI VFPSNA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..496] PSI-BLAST 109.0 Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • electron carrier activity
    		•  4.64931978461551 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  3.99744233006162 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  3.76307535769621 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • demethylase activity
    		•  3.40807632433846 bayes_pls_golite062009
  • oxygen binding
    		•  3.29945075872446 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  3.16634614522939 bayes_pls_golite062009
  • retinoic acid binding
    		•  3.04897926497756 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.94610675710811 bayes_pls_golite062009
  • retinoid binding
    		•  2.60220937953757 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • isoprenoid binding
    		•  2.47826119804163 bayes_pls_golite062009
  • thromboxane-A synthase activity
    		•  2.45281910634006 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  1.65569090470706 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.64204907906991 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • binding
    		•  1.2866152532988 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • protein binding
    		•  0.836411857417911 bayes_pls_golite062009
  • ecdysteroid 22-hydroxylase activity
    		•  0.7601272997427 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.658520486133281 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • iron ion binding
    		•  0.529598228513719 bayes_pls_golite062009
  • cation binding
    		•  0.510556740388808 bayes_pls_golite062009
  • metal ion binding
    		•  0.510556740388808 bayes_pls_golite062009
  • ion binding
    		•  0.503326724714616 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.450436868179747 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  0.0888154993183798 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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