YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: cyp-25A5

General Information:
Name(s) found: cyp-25A5 / CE17056 [WormBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • WBGene00018326 locus:cyp-25A5 cytochrome P450 status:Predicted UniProt:O44485 protein_id:CCD71131.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 477 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: electron transport [IEALink to PubMed article]
    Molecular Function: iron ion binding [IEALink to PubMed article]
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    heme binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILIISTIF FTIITFISYI IWRRHSIFKL RSSIGIPGPP GYCKVMKFYS KNNFSLYCGT  60
   61 QLHITVSEEE DIKEIFIQNF SNFSDRMTPN IFGMNQLNQS LLQNTYATGW KHTRSAVAPI 120
  121 FSTGKMKAMH ETLVSKIDIF LEVLKEKSSS GQKWDIFDNF QSLSLDIIGK CAFAIDSNCQ 180
  181 RDRIDLFYVQ ARKFVGAVAL KKSWILPVSL ILPELSWLWR FLYKFSDLSA AELPLVKGLV 240
  241 DLYDRRRAGE GGNDSTDLLN LLIRRETIGK MTKREVIENC FAFLIAGYET TSTAMMFSAY 300
  301 LLAEYPIVQQ KLYEEIKKTK ESAGLNYDSI HNMKYSDCVY KESLRFYPPT THFTNRVCLN 360
  361 DMTIQGQIYP KDSTLKVQPH TIHRNPANWE SPDEFQPERF ENWEEKSSSL KWIPFGVGPR 420
  421 YCVGMRFAEM EFKTTIAKLL DTFELSLVPG DPPMIPETNG VIFRPRCPVR LNLKLRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..477] PSI-BLAST 93.522879 Crystal Structure of Human Microsomal P450 3A4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  4.64322346579269 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • oxygen binding
    		•  3.29945075872446 bayes_pls_golite062009
  • demethylase activity
    		•  2.80780658333504 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  2.60901411823382 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  2.36480328243514 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  2.33937429425924 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  2.24146036195166 bayes_pls_golite062009
  • steroid 7-alpha-hydroxylase activity
    		•  2.21042366294727 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  2.15105968497418 bayes_pls_golite062009
  • retinoid binding
    		•  1.91237853759594 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.78853880472253 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • retinoic acid binding
    		•  1.55035199545719 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  1.48500938886158 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • corticosterone 18-monooxygenase activity
    		•  1.4105861338158 bayes_pls_golite062009
  • steroid 11-beta-monooxygenase activity
    		•  1.4105861338158 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.203772707673481 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle