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Protein Overview: SPBC543.09

General Information:
Name(s) found: SPBC543.09 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • mitochondrial m-AAA protease [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 773 amino acids

    Gene Ontology:
    Cellular Component: m-AAA complex [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    integral to membrane [IEA]
    Biological Process: protein import into mitochondrial intermembrane space [ISSLink to PubMed article]
    generation of precursor metabolites and energy [RCALink to PubMed article]
    proteolysis [ISS]
    signal peptide processing [ISSLink to PubMed article]
    mitochondrial respiratory chain complex assembly [ISSLink to PubMed article]
    Molecular Function: ATPase activity [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]
    zinc ion binding [IEA]
    metalloendopeptidase activity [IEA]
    metallopeptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNPFLTFRA PTRKTGDYLV SKFVKKDNFS SLRLARAYTF STRSTAVSQF SLLSLSQRSF  60
   61 QSLKINKGIP EKHKIPLISS KQFSVTSKRS QNGSSGSNSD ANGRKNGQKN DDSKKKGLNG 120
  121 NDPKKVFEIA LNGNTILGGI LVAYILYNVL SPNANMQEIT WQDFRQQFLD KGLVERLVVV 180
  181 NRNMVRVILR GGVASGSGQY YFSIGSIDSF DRKLEDAQRQ LGIPPSEFVP VAYHDEVSVL 240
  241 ATLLSFAPTL LIIGSVIYLS RRASGAAGGG QGGIFGIGKS RAKMFNHETD IKIKFADVAG 300
  301 VDEAKEEIME FVKFLKNPKF YERLGAKIPR GAILSGPPGT GKTLLAKATA GEANVPFLSV 360
  361 SGSEFLEMFV GVGPSRVRDL FATARKNAPC IIFIDEIDAI GKARGRGGQF GSNDERESTL 420
  421 NQLLVEMDGF TSSEHIVVFA GTNRPDVLDP ALLRPGRFDR QITIDRPDIG GREQIFKVHL 480
  481 KHIKAADNID LIAKRLAVLT SGFTGADIMN VCNEGALIAA RSNSNEVQMV HFEQAIERVT 540
  541 AGLEKKSRVL SPEEKNTVAH HEAGHAVAGW FMEYVDPLLK VSIIPRAQAL GYASYLPKDQ 600
  601 YLMSRGQILD QMGMALAGRV SEEIFFGPEK ITSGASDDFQ KVTRMAQAYV TQYGMSPTVG 660
  661 TIAYPIDTRE TVQKPFSEAT AQMIDEEIRK LVKHAYERTK KLLLEHKQGL ENIAQRLLQK 720
  721 EVITYNEVET ILGPRPYAYK HLNISELMRQ SEYKNDHDPR NPPIPPSPQQ PSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] deduced N/A No confident structure predictions are available.
    2 View Details [124..156] PSI-BLAST 72.0 VCP/p97
    3 View Details [157..671] PSI-BLAST 25.0 N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
    4 View Details [672..773] PSI-BLAST 114.0 EDTA treated

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.57926427233638 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.61311581579476 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.50934147358924 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.97313818590443 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.97313818590443 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.831762535895849 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.640772201693186 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.63468044350616 bayes_pls_golite062009
  • GTP binding
    		•  0.621689261700018 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • protein transporter activity
    		•  0.498432226280822 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  0.46842047319323 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • protein binding
    		•  0.378225828131122 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
    		• 0.3586311431823 bayes_pls_golite062009
  • signal recognition particle binding
    		•  0.29390189699022 bayes_pls_golite062009
  • DNA binding
    		•  0.143403729737365 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.11674780318211 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0147430141176288 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle