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The hydrolysis of a peptide bond or bonds within a protein as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. The removal of the signal peptide from a nascent protein during cotranslational membrane targeting. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. Any protein maturation process achieved by the cleavage of peptide bonds. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. The chemical reactions and pathways by which individual cells transform chemical substances. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: signal peptide processing
Acc: GO:0006465
Aspect: Biological Process
Desc: The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
Synonyms:
  • leader peptide processing
Proteins in PDR annotated with:
   This term: 70 [Search]
   Term or descendants: 70 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006465 - signal peptide processing (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle