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Protein Overview: cki2

General Information:
Name(s) found: cki2 / SPBP35G2.05c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • serine/threonine protein kinase Cki2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 435 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    fungal-type vacuole membrane [IDALink to PubMed article]
    Biological Process: signal transduction [RCALink to PubMed article]
    cell morphogenesis [IMPLink to PubMed article]
    regulation of endocytosis [ISS]
    protein amino acid phosphorylation [TASLink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    protein serine/threonine kinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSQTSVVGV HYRVGRKIGE GSFGVIFDGM NLLNNQLIAI KFEPKKSEAP QLRDEYRTYK  60
   61 LLVGNAGIPN VYYFGQEGLH NILVIDLLGP SLEDLFEWCG RRFSVKTVAM TAKQMLSRVQ 120
  121 TIHEKNLVYR DIKPDNFLIG RPSSRNANMV YMVDFGMAKY YRDPKTKQHI PYSERKSLSG 180
  181 TARYMSINTH LGREQSRRDD LESLGHVFMY FLRGSLPWQG LKAANNKHKY EKISEKKQST 240
  241 SISELCAGFP NEFSKYMTYV RSLEFDEEPD YAFLQELFDD VLRANGDTND GVYDWMLLND 300
  301 GKGWESSSSH FSVVAMKRRK NYLGLNVVQN DDSRKKNSTL QTQNMRFKSS YGVRGPRNYS 360
  361 SFDALPSKNA PLVRQEQSAS KKTIYAHSSR GYDRVRPMYV SQPSNNAVGV NHPNDNSDSE 420
  421 AKGGFFDMIC CRCFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..298] PSI-BLAST 53.39794 BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP
    2 View Details [299..435] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.36057410204148 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.18678745551825 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  2.04316366039331 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • receptor activity
    		•  1.9592549430179 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.95775692939268 bayes_pls_golite062009
  • signal transducer activity
    		•  1.95775692939268 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.67588659181633 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.63027742934354 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  1.47162554695064 bayes_pls_golite062009
  • peptidase activity
    		•  1.4194137915074 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.02752755983942 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • hydrolase activity
    		•  0.950393847838778 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.794058505655489 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.775404673285876 bayes_pls_golite062009
  • DNA binding
    		•  0.714163549867672 bayes_pls_golite062009
  • transcription factor activity
    		•  0.563262875317016 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.468913717372328 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.451090007290896 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • growth factor binding
    		•  0.39228429305663 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.284465446035567 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.26024936404169 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.205652638854091 bayes_pls_golite062009
  • protein kinase C activity
    		•  0.0795689006739899 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle