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Protein Overview: CG1494-PA

General Information:
Name(s) found: CG1494-PA / FBpp0076889 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG1494 (CG1494, FBgn0031169). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21156384..21163160. It has the cytological map location 19F3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled to transmembrane movement of substances; transporter activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1570 amino acids

    Gene Ontology:
    Cellular Component: ATP-binding cassette (ABC) transporter complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    ATPase activity, coupled to transmembrane movement of substances [ISS]
    transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVRSYIRKF LLMNWKNHKL QLANPLELLV ILLVPPLFTL VAVLMRFFIP VNHRSDTVYD  60
   61 PIDLDRSWMQ MVEKLEKARQ VADTYNVKGN PFTPHLVIGW APKRYGIFQA MMRRVQKQIE 120
  121 PMTSVGFEDC EEMRESVIEN GLFAGLCFDG SPFVEDQVFE EDTLESYSNI QPMLNYTILL 180
  181 PSELRMLDGD FRMANWMTLY NDDPNTFVLT RLNQPYEGGF VGYVREGFIR LQKSVSESFL 240
  241 VLTSHKSLPT IQIRRFPITG REQDPLMGNL NYGMPFIIII GFLFPAQLFV WQVVSEKQSQ 300
  301 VRQFLINMNI GNLIHFVSWY LKGLIYEMIS SLIIAALLKI RWDQDHGVLT QTPWYILILV 360
  361 LFCYNCAAVA FAIMVAAFFR NALNAVRVLT ILWIMSYVPT FILSNNLEGN IHALRYVSYA 420
  421 LPNVVATLVI EFLIERESIV HITWEDSGYR LNYDGGHITV TASSWIFMLN ALVYCAIGLY 480
  481 VDMWRGGDRS GKKMKKPNTN ASVQEDPYHE RGDSFTHQGQ AIGVNSTKIY EVEPSHRRFK 540
  541 LKIKKLCKRF ATNDRPALNL FSWNVYENEV TVLMGHNGCG KSTLLKILAG LVEPSRGTVM 600
  601 ISSHNIQTER KAASMELGIA FGHDMLLTGF TVIDYLRFIC RVKGLHNNIE IDGQSNYFLN 660
  661 VLQIGGLKTK RIRTLTDRDL CLVSICCAFV GNSPIILIDD VHSDLDKRTQ SLVWNLINEE 720
  721 KSKRTIILVS NSPALAENIA DRMAIMSNGE LKCTGTKPFL KNMYGHGYRL TCVKGKNYKR 780
  781 DELFGMMNSY MPNMSIERDI GYKVTFVLEN KFEDQFPMLI DDLEENMQQL GVVSFRIRDT 840
  841 SMEEIFLRFG CEDNDQSGAF QSHENAQVLL EEYYSTLAEA NEKGRRTGWK LFFLHGRAVI 900
  901 YKRWIAAHRH WIVLIFEVLA MALVAVCTFS SIFIYGKNYE LEPLTFNLSQ LHTVDAFVEL 960
  961 FSEEEDVKDM HAYYTELLYW YDAHVATLTK NRHNAYALLT QNQFTAHVNS RYIFGATFDQ1020
 1021 KIVTAWFNNI PLHSAPYALN VVHNAVARHL FDEEATIDVT LAPLPFRTAI NTFPPSSHTF1080
 1081 GGCLAFGICF VLTFIWPAFA IYMITERGSL LKKQQFLAGV RVCSYWTFTV LYDLLFLLIF1140
 1141 CACVVVMVAL YENPNHDVML YGYISVTLML GGFWVILLAY LMASLCRNPC YGFLWLCGIN1200
 1201 SIGLVCFSQF YRTHPESMLL EPTFMAMYTV ATVICKLFMI YEFKLICMDP VVNFTSVEVF1260
 1261 KSECLSITGA NNSGKTTLLK VVVNETKMNA GQLWIHDYSV NTHRVQCYRM VGYCPQKDSL1320
 1321 PSEFTPRELL YIHAMLQGHR HRIGRELSEA LLRLVGLTPC WNRSVRMCTT GQIRRLYFAY1380
 1381 AVLGSPDLIC VDGVPAGLDP TGKRIILMMT STMQAMGSSF LYTMLTGLDA ERLSLRTPLL1440
 1441 LEGQLWMIRP MDTETENYKS GYQLEVRFKR KVNPNVSMSR ATWNLINHFP MSPNKKFSAF1500
 1501 MEIKFPDAVL TIERDDSMVF VLPLGTTTFS EIFLTLRKDA FEMNIEDYFI TRNMLVGFQI1560
 1561 FTYDQHQDNP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] MSA 1.243991 View MSA. No confident structure predictions are available.
    2 View Details [170..775] PSI-BLAST 85.09691 No description for 2hydA was found.
    3 View Details [776..909] PSI-BLAST 25.39794 No description for 2ix8A was found.
    4 View Details [910..1226] deduced N/A No confident structure predictions are available.
    5 View Details [1227..1570] PSI-BLAST 84.154902 No description for 2d62A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.57844095962502 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.5689620139321 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.55992639965745 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.50005167063544 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.98276715440477 bayes_pls_golite062009
  • ATPase activity
    		•  4.69795387297193 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  4.45923622153365 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  4.39781350157199 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  4.38133275795019 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  4.38085303582726 bayes_pls_golite062009
  • transporter activity
    		•  3.71239480053329 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  3.19399273923292 bayes_pls_golite062009
  • hydrolase activity
    		•  3.14498892233323 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.13960906549884 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.1318898376276 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • ATP binding
    		•  3.01346604299372 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.00745742755195 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  2.97119034312001 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  2.96271391116269 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.9271291809464 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  2.91131545957759 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  2.70262534541085 bayes_pls_golite062009
  • ribonucleotide binding
    		•  2.70178191749524 bayes_pls_golite062009
  • purine nucleotide binding
    		•  2.6583477492092 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.63419811368692 bayes_pls_golite062009
  • nucleotide binding
    		•  2.62374702628143 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.26365379756656 bayes_pls_golite062009
    		• 2.20174656498665 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  2.12727614888121 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  1.88153949603611 bayes_pls_golite062009
  • lipid transporter activity
    		•  1.74534601529986 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  1.57734504779864 bayes_pls_golite062009
  • binding
    		•  1.40652776383476 bayes_pls_golite062009
  • carbohydrate-transporting ATPase activity
    		•  1.37859980472197 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  1.37783759788533 bayes_pls_golite062009
  • carbohydrate-importing ATPase activity
    		•  1.27327946933978 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  1.21226071573355 bayes_pls_golite062009
  • peptide transporter activity
    		•  1.19353064661766 bayes_pls_golite062009
  • cation channel activity
    		•  0.997064416395892 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  0.959018069837069 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • potassium channel activity
    		•  0.843657228494419 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.688632087597536 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.562664200036023 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.559798751382976 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.50574216781413 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.501012663775049 bayes_pls_golite062009
  • signal transducer activity
    		•  0.501012663775049 bayes_pls_golite062009
  • protein transporter activity
    		•  0.498432226280822 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.43332053110728 bayes_pls_golite062009
  • glucoside transmembrane transporter activity
    		•  0.31429820040527 bayes_pls_golite062009
  • alpha-glucoside transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • maltose transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • disaccharide transmembrane transporter activity
    		•  0.309333293394255 bayes_pls_golite062009
  • oligosaccharide transmembrane transporter activity
    		•  0.304521826432814 bayes_pls_golite062009
  • oligosaccharide-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • maltose-transporting ATPase activity
    		•  0.304521826432814 bayes_pls_golite062009
  • gated channel activity
    		•  0.299411774392227 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  0.248918847596573 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.219473333671469 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • ion channel activity
    		•  0.154779598791225 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.134817721656507 bayes_pls_golite062009
  • channel activity
    		•  0.134817721656507 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.126911677161968 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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