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View Structure Prediction Details

Protein: CG1494-PA
Organism: Drosophila melanogaster
Length: 1570 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1494-PA.

Description E-value Query
Range		 Subject
Range
gi|76652817 - gi|76652817|ref|XP_582132.2| PREDICTED: similar to ATP-binding cassette, sub-family A member 3 [Bos ...
 970.0 [0..112] [1570..6]

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Predicted Domain #1
Region A:
Residues: [1-169] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVRSYIRKF LLMNWKNHKL QLANPLELLV ILLVPPLFTL VAVLMRFFIP VNHRSDTVYD  60
   61 PIDLDRSWMQ MVEKLEKARQ VADTYNVKGN PFTPHLVIGW APKRYGIFQA MMRRVQKQIE 120
  121 PMTSVGFEDC EEMRESVIEN GLFAGLCFDG SPFVEDQVFE EDTLESYSN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [170-775] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQPMLNYTIL LPSELRMLDG DFRMANWMTL YNDDPNTFVL TRLNQPYEGG FVGYVREGFI  60
   61 RLQKSVSESF LVLTSHKSLP TIQIRRFPIT GREQDPLMGN LNYGMPFIII IGFLFPAQLF 120
  121 VWQVVSEKQS QVRQFLINMN IGNLIHFVSW YLKGLIYEMI SSLIIAALLK IRWDQDHGVL 180
  181 TQTPWYILIL VLFCYNCAAV AFAIMVAAFF RNALNAVRVL TILWIMSYVP TFILSNNLEG 240
  241 NIHALRYVSY ALPNVVATLV IEFLIERESI VHITWEDSGY RLNYDGGHIT VTASSWIFML 300
  301 NALVYCAIGL YVDMWRGGDR SGKKMKKPNT NASVQEDPYH ERGDSFTHQG QAIGVNSTKI 360
  361 YEVEPSHRRF KLKIKKLCKR FATNDRPALN LFSWNVYENE VTVLMGHNGC GKSTLLKILA 420
  421 GLVEPSRGTV MISSHNIQTE RKAASMELGI AFGHDMLLTG FTVIDYLRFI CRVKGLHNNI 480
  481 EIDGQSNYFL NVLQIGGLKT KRIRTLTDRD LCLVSICCAF VGNSPIILID DVHSDLDKRT 540
  541 QSLVWNLINE EKSKRTIILV SNSPALAENI ADRMAIMSNG ELKCTGTKPF LKNMYGHGYR 600
  601 LTCVKG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.09691
Match: 2hydA
Description: No description for 2hydA was found.

Predicted functions:

Term Confidence Notes
ATPase activity, coupled to transmembrane movement of substances 5.57844095962502 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 5.57813579764186 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 5.57813579764186 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 5.5689620139321 bayes_pls_golite062009
primary active transmembrane transporter activity 5.55992639965745 bayes_pls_golite062009
active transmembrane transporter activity 5.50005167063544 bayes_pls_golite062009
ATPase activity, coupled 4.98276715440477 bayes_pls_golite062009
ATPase activity 4.69795387297193 bayes_pls_golite062009
nucleoside-triphosphatase activity 4.45923622153365 bayes_pls_golite062009
pyrophosphatase activity 4.39781350157199 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 4.38133275795019 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.38085303582726 bayes_pls_golite062009
transporter activity 3.71239480053329 bayes_pls_golite062009
ion transmembrane transporter activity 3.35436118751376 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.19399273923292 bayes_pls_golite062009
hydrolase activity 3.14498892233323 bayes_pls_golite062009
transmembrane transporter activity 3.13960906549884 bayes_pls_golite062009
substrate-specific transporter activity 3.1318898376276 bayes_pls_golite062009
cation transmembrane transporter activity 3.08390071341252 bayes_pls_golite062009
ATP binding 3.01346604299372 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00745742755195 bayes_pls_golite062009
drug transmembrane transporter activity 2.97119034312001 bayes_pls_golite062009
adenyl ribonucleotide binding 2.96271391116269 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 2.9271291809464 bayes_pls_golite062009
adenyl nucleotide binding 2.91131545957759 bayes_pls_golite062009
purine ribonucleotide binding 2.70262534541085 bayes_pls_golite062009
ribonucleotide binding 2.70178191749524 bayes_pls_golite062009
purine nucleotide binding 2.6583477492092 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 2.63419811368692 bayes_pls_golite062009
nucleotide binding 2.62374702628143 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.40292717311506 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.26365379756656 bayes_pls_golite062009
2.20174656498665 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 2.12727614888121 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 1.88153949603611 bayes_pls_golite062009
lipid transporter activity 1.74534601529986 bayes_pls_golite062009
sugar transmembrane transporter activity 1.57734504779864 bayes_pls_golite062009
binding 1.40652776383476 bayes_pls_golite062009
carbohydrate-transporting ATPase activity 1.37859980472197 bayes_pls_golite062009
peptide-transporting ATPase activity 1.37783759788533 bayes_pls_golite062009
carbohydrate-importing ATPase activity 1.27327946933978 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 1.21226071573355 bayes_pls_golite062009
peptide transporter activity 1.19353064661766 bayes_pls_golite062009
cation channel activity 0.997064416395892 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.959018069837069 bayes_pls_golite062009
motor activity 0.87979065815418 bayes_pls_golite062009
potassium channel activity 0.843657228494419 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.767424210804186 bayes_pls_golite062009
voltage-gated cation channel activity 0.688632087597536 bayes_pls_golite062009
voltage-gated channel activity 0.562664200036023 bayes_pls_golite062009
voltage-gated ion channel activity 0.559798751382976 bayes_pls_golite062009
DNA-dependent ATPase activity 0.50574216781413 bayes_pls_golite062009
molecular transducer activity 0.501012663775049 bayes_pls_golite062009
signal transducer activity 0.501012663775049 bayes_pls_golite062009
protein transporter activity 0.498432226280822 bayes_pls_golite062009
anion transmembrane transporter activity 0.43332053110728 bayes_pls_golite062009
glucoside transmembrane transporter activity 0.31429820040527 bayes_pls_golite062009
alpha-glucoside transmembrane transporter activity 0.309333293394255 bayes_pls_golite062009
maltose transmembrane transporter activity 0.309333293394255 bayes_pls_golite062009
disaccharide transmembrane transporter activity 0.309333293394255 bayes_pls_golite062009
oligosaccharide transmembrane transporter activity 0.304521826432814 bayes_pls_golite062009
oligosaccharide-transporting ATPase activity 0.304521826432814 bayes_pls_golite062009
maltose-transporting ATPase activity 0.304521826432814 bayes_pls_golite062009
gated channel activity 0.299411774392227 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 0.248918847596573 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 0.219473333671469 bayes_pls_golite062009
protein binding 0.193768631623192 bayes_pls_golite062009
ion channel activity 0.154779598791225 bayes_pls_golite062009
passive transmembrane transporter activity 0.134817721656507 bayes_pls_golite062009
channel activity 0.134817721656507 bayes_pls_golite062009
substrate-specific channel activity 0.126911677161968 bayes_pls_golite062009
cation-transporting ATPase activity 0.0536898657672154 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [776-909] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNYKRDELFG MMNSYMPNMS IERDIGYKVT FVLENKFEDQ FPMLIDDLEE NMQQLGVVSF  60
   61 RIRDTSMEEI FLRFGCEDND QSGAFQSHEN AQVLLEEYYS TLAEANEKGR RTGWKLFFLH 120
  121 GRAVIYKRWI AAHR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.39794
Match: 2ix8A
Description: No description for 2ix8A was found.

Predicted Domain #4
Region A:
Residues: [910-1226] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HWIVLIFEVL AMALVAVCTF SSIFIYGKNY ELEPLTFNLS QLHTVDAFVE LFSEEEDVKD  60
   61 MHAYYTELLY WYDAHVATLT KNRHNAYALL TQNQFTAHVN SRYIFGATFD QKIVTAWFNN 120
  121 IPLHSAPYAL NVVHNAVARH LFDEEATIDV TLAPLPFRTA INTFPPSSHT FGGCLAFGIC 180
  181 FVLTFIWPAF AIYMITERGS LLKKQQFLAG VRVCSYWTFT VLYDLLFLLI FCACVVVMVA 240
  241 LYENPNHDVM LYGYISVTLM LGGFWVILLA YLMASLCRNP CYGFLWLCGI NSIGLVCFSQ 300
  301 FYRTHPESML LEPTFMA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1227-1570] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTVATVICK LFMIYEFKLI CMDPVVNFTS VEVFKSECLS ITGANNSGKT TLLKVVVNET  60
   61 KMNAGQLWIH DYSVNTHRVQ CYRMVGYCPQ KDSLPSEFTP RELLYIHAML QGHRHRIGRE 120
  121 LSEALLRLVG LTPCWNRSVR MCTTGQIRRL YFAYAVLGSP DLICVDGVPA GLDPTGKRII 180
  181 LMMTSTMQAM GSSFLYTMLT GLDAERLSLR TPLLLEGQLW MIRPMDTETE NYKSGYQLEV 240
  241 RFKRKVNPNV SMSRATWNLI NHFPMSPNKK FSAFMEIKFP DAVLTIERDD SMVFVLPLGT 300
  301 TTFSEIFLTL RKDAFEMNIE DYFITRNMLV GFQIFTYDQH QDNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.154902
Match: 2d62A
Description: No description for 2d62A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle