General Information: |
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Name(s) found: |
FBpp0306705
[FlyBase]
Pi3K92E-PB / FBpp0083349 [FlyBase] Pi3K92E-PA / FBpp0083348 [FlyBase] |
Description(s) found:
Found 49 descriptions. SHOW ALL |
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Organism: | Drosophila melanogaster |
Length: | 1088 amino acids |
Gene Ontology: |
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Cellular Component: |
1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex
[IPI][NAS]
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Biological Process: |
positive regulation of growth
[TAS]
regulation of multicellular organism growth [IMP][NAS] germ-band shortening [IMP] positive regulation of translation [IMP] insulin receptor signaling pathway [NAS][TAS] regulation of cell size [IMP][NAS] phosphoinositide phosphorylation [IDA][ISS][TAS] metamorphosis [IMP] larval development [IMP] larval salivary gland morphogenesis [IMP] instar larval development [IMP] regulation of dendrite development [IMP] response to oxidative stress [IMP] positive regulation of cell growth [NAS][TAS] positive regulation of cell size [TAS] autophagy [IMP] positive regulation of imaginal disc growth [IMP] phosphorylation [NAS] positive regulation of organ growth [IMP][NAS] regulation of organ growth [NAS] regulation of cell proliferation [IMP] larval feeding behavior [IMP] phosphoinositide-mediated signaling [IEA] oogenesis [IMP] diapause [IMP] cell growth [TAS] |
Molecular Function: |
lipid kinase activity
[IDA]
phosphatidylinositol-4,5-bisphosphate 3-kinase activity [IDA][ISS] phosphoinositide 3-kinase activity [ISS] binding [IEA] phosphatidylinositol-4-phosphate 3-kinase activity [IDA][ISS] 1-phosphatidylinositol-3-kinase activity [IDA][ISS][NAS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MNMMDNRALA YVAHQPKYET PPEEAEPPCM RFSVNLWKNE MLNWVDLICL LPNGFLLELR 60 61 VNPANTIQVI KVEMVNQAKQ MPLGYVIKEA CEYQVYGIST FNIEPYTDET KRLSEVQPYF 120 121 GILSLGERTD TTSFSSDYEL TKMVNGMIGT TFDHNRTHGS PEIDDFRLYM TQTCDNIELE 180 181 RSAYTWQQRL LYEHPLRLAN STKMPELIRE RHPTRTFLIV VKNENDQSTF TLSVNEQDTP 240 241 FSLTESTLQK MNRSQMKMND RTSDYILKVS GRDEYLLGDY PLIQFLYIQE MLSDSAVPNV 300 301 VLQSVYRLES YINHHNEQAM VTKRPLPKKR TVHLHKSISS LWDMGNYFQL TLHSISNVNF 360 361 DKTRALKVGV HVCLYHGDKK LCAQRSTDSP NGNFDTFLFN DLVMDFDIQM RNLPRMTRLC 420 421 IVIFEVTKMS RSKKSSNNKD IALKDVPYNK NPLAWVNTTI FDHKDILRTG RHTLYTWTYA 480 481 DDIQSVEVFH PLGTIEPNPR KEECALVDLT FLSSGTGTVR YPSEEVVLQY AADREQVNRL 540 541 QRQLAGPEKP IKELKELMAN YTGLDKIYEM VDQDRNAIWE RRNDILRELP EELSILLHCV 600 601 YWKERDDVAD MWYLLKQWPL ISIERSLELL DYAYPDPAVR RFAIRCLHFL KDEDLLLYLL 660 661 QLVQAIKHES YLESDLVVFL LERALRNQRI GHYFFWHLRS EMQTPSMQTR FGLLLEVYLK 720 721 GCKHHVAPLR KQLHVLEKLK QGSLIAKKGS KEKVKTMLQD FLRDQRNSAV FQNIQNPLNP 780 781 SFRCSGVTPD RCKVMDSKMR PLWVVFENAD VNASDVHIIF KNGDDLRQDM LTLQMLRVMD 840 841 QLWKRDGMDF RMNIYNCISM EKSLGMIEVV RHAETIANIQ KEKGMFSATS PFKKGSLLSW 900 901 LKEHNKPADK LNKAINEFTL SCAGYCVATY VLGVADRHSD NIMVKRNGQL FHIDFGHILG 960 961 HFKEKLGVRR ERVPFVLTHD FVYVINKGFN DRESKEFCHF QELCERAFLV LRKHGCLILS1020 1021 LFSMMISTGL PELSSEKDLD YLRETLVLDY TEEKAREHFR AKFSEALANS WKTSLNWASH1080 1081 NFSKNNKQ |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Domains predicted:
# | Region(s) | Method | Confidence | Match Description | |
1 | View Details | [1..134] | ![]() |
31.0 | No description for 2v1yA was found. |
2 | View Details | [135..1088] | ![]() |
1000.0 | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Functions predicted (by domain):
# | Gene Ontology predictions | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 | No functions predicted. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 |
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.94 |
Source: Reynolds et al. (2008)