YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling. The process whereby a signal is passed from the insulin receptor to components of the phosphoinositide 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. Any process that modulates the frequency, rate or extent of insulin receptor signaling. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. Any process that increases the frequency, rate or extent of insulin receptor signaling. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: insulin receptor signaling pathway
Acc: GO:0008286
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
Synonyms:
  • insulin receptor signalling pathway
  • daf-2 receptor signaling pathway
Proteins in PDR annotated with:
   This term: 112 [Search]
   Term or descendants: 161 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008286 - insulin receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle