| Protein: | FBpp0306705, Pi3... |
| Organism: | Drosophila melanogaster |
| Length: | 1088 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0306705, Pi3....
| Description | E-value | Query Range |
Subject Range |
|
|
1056.0 | [0..26] | [1087..1] |
|
Region A: Residues: [1-134] |
1 11 21 31 41 51
| | | | | |
1 MNMMDNRALA YVAHQPKYET PPEEAEPPCM RFSVNLWKNE MLNWVDLICL LPNGFLLELR 60
61 VNPANTIQVI KVEMVNQAKQ MPLGYVIKEA CEYQVYGIST FNIEPYTDET KRLSEVQPYF 120
121 GILSLGERTD TTSF
|
| Detection Method: |  |
| Confidence: | 31.0 |
| Match: | 2v1yA |
| Description: | No description for 2v1yA was found. |
|
Region A: Residues: [135-1088] |
1 11 21 31 41 51
| | | | | |
1 SSDYELTKMV NGMIGTTFDH NRTHGSPEID DFRLYMTQTC DNIELERSAY TWQQRLLYEH 60
61 PLRLANSTKM PELIRERHPT RTFLIVVKNE NDQSTFTLSV NEQDTPFSLT ESTLQKMNRS 120
121 QMKMNDRTSD YILKVSGRDE YLLGDYPLIQ FLYIQEMLSD SAVPNVVLQS VYRLESYINH 180
181 HNEQAMVTKR PLPKKRTVHL HKSISSLWDM GNYFQLTLHS ISNVNFDKTR ALKVGVHVCL 240
241 YHGDKKLCAQ RSTDSPNGNF DTFLFNDLVM DFDIQMRNLP RMTRLCIVIF EVTKMSRSKK 300
301 SSNNKDIALK DVPYNKNPLA WVNTTIFDHK DILRTGRHTL YTWTYADDIQ SVEVFHPLGT 360
361 IEPNPRKEEC ALVDLTFLSS GTGTVRYPSE EVVLQYAADR EQVNRLQRQL AGPEKPIKEL 420
421 KELMANYTGL DKIYEMVDQD RNAIWERRND ILRELPEELS ILLHCVYWKE RDDVADMWYL 480
481 LKQWPLISIE RSLELLDYAY PDPAVRRFAI RCLHFLKDED LLLYLLQLVQ AIKHESYLES 540
541 DLVVFLLERA LRNQRIGHYF FWHLRSEMQT PSMQTRFGLL LEVYLKGCKH HVAPLRKQLH 600
601 VLEKLKQGSL IAKKGSKEKV KTMLQDFLRD QRNSAVFQNI QNPLNPSFRC SGVTPDRCKV 660
661 MDSKMRPLWV VFENADVNAS DVHIIFKNGD DLRQDMLTLQ MLRVMDQLWK RDGMDFRMNI 720
721 YNCISMEKSL GMIEVVRHAE TIANIQKEKG MFSATSPFKK GSLLSWLKEH NKPADKLNKA 780
781 INEFTLSCAG YCVATYVLGV ADRHSDNIMV KRNGQLFHID FGHILGHFKE KLGVRRERVP 840
841 FVLTHDFVYV INKGFNDRES KEFCHFQELC ERAFLVLRKH GCLILSLFSM MISTGLPELS 900
901 SEKDLDYLRE TLVLDYTEEK AREHFRAKFS EALANSWKTS LNWASHNFSK NNKQ
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1e7vA |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 1-phosphatidylinositol-3-kinase activity | 8.12544462052019 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 8.10715314025226 | bayes_pls_golite062009 |
| lipid kinase activity | 5.98454599133418 | bayes_pls_golite062009 |
| protein kinase activity | 5.63683237027974 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 5.59422890717019 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 4.51744163880238 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| phosphatidylinositol-4-phosphate 3-kinase activity | 4.06630000313653 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| binding | 2.31930216202447 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.97522797979421 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 1.16085055664961 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| profilin binding | 1.08496596907016 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.58590430118616 | bayes_pls_golite062009 |
| insulin receptor activity | 0.585036697436369 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| MAP kinase activity | 0.5066845540941 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.388422171413648 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 0.33808087202461 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.307012041236766 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| insulin binding | 0.147382876071569 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| cation channel activity | 0.0880130476088317 | bayes_pls_golite062009 |
| nucleic acid binding | 0.0723883138085393 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| cation binding | 0.046173055856133 | bayes_pls_golite062009 |
| metal ion binding | 0.046173055856133 | bayes_pls_golite062009 |
| ion binding | 0.0389662058697694 | bayes_pls_golite062009 |
| transcription regulator activity | 0.0336051357091371 | bayes_pls_golite062009 |
| PTB domain binding | 0.0116623342611808 | bayes_pls_golite062009 |
| DNA binding | 0.0091533228439924 | bayes_pls_golite062009 |
| protein tag | 0.00311613478935058 | bayes_pls_golite062009 |
