Protein Overview: PSN2_RAT

General Information:
Name(s) found:	PSN2_RAT [Swiss-Prot]
Description(s) found: Found 22 descriptions. SHOW ALL	Presenilin-2 OS=Rattus norvegicus GN=Psen2 PE=1 SV=2 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	448 amino acids
Gene Ontology:
Cellular Component:	Golgi membrane [IEA] endoplasmic reticulum [UNKNOWN][IEA] Golgi apparatus [UNKNOWN][IEA] neuronal cell body [UNKNOWN][IEA] cellular_component [ND] plasma membrane [UNKNOWN] membrane fraction [UNKNOWN][IEA] endoplasmic reticulum membrane [IEA] integral to plasma membrane [UNKNOWN][IEA] Z disc [UNKNOWN][IEA] membrane [IEA] integral to membrane [IEA] cytosol [UNKNOWN][IEA]
Biological Process:	embryonic development [UNKNOWN][IEA] regulation of epidermal growth factor receptor activity [UNKNOWN][IEA] locomotion [UNKNOWN][IEA] protein transport [UNKNOWN][IEA] brain morphogenesis [UNKNOWN][IEA] T cell activation during immune response [UNKNOWN][IEA] cardiac muscle contraction [UNKNOWN][IEA] memory [UNKNOWN][IEA] induction of apoptosis by extracellular signals [UNKNOWN] hemopoietic progenitor cell differentiation [UNKNOWN][IEA] learning or memory [UNKNOWN] thymus development [UNKNOWN][IEA] embryonic limb morphogenesis [UNKNOWN][IEA] lung alveolus development [UNKNOWN][IEA] response to hypoxia [IEP] forebrain development [UNKNOWN][IEA] hair follicle development [UNKNOWN][IEA] calcium ion transport [UNKNOWN][IEA] apoptosis [UNKNOWN] regulation of synaptic plasticity [UNKNOWN][IEA] protein maturation [UNKNOWN] protein maturation by peptide bond cleavage [UNKNOWN][IEA] cell fate specification [UNKNOWN][IEA] beta-amyloid metabolic process [UNKNOWN][IEA] T cell receptor signaling pathway [UNKNOWN][IEA] dorsal/ventral neural tube patterning [UNKNOWN][IEA] membrane protein intracellular domain proteolysis [UNKNOWN] cellular protein metabolic process [UNKNOWN][IEA] anagen [UNKNOWN][IEA] myeloid leukocyte differentiation [UNKNOWN][IEA] Notch signaling pathway [UNKNOWN][IEA] membrane protein ectodomain proteolysis [UNKNOWN][IEA] somitogenesis [UNKNOWN][IEA] positive regulation of catalytic activity [UNKNOWN][IEA] negative regulation of protein amino acid phosphorylation [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] positive regulation of apoptosis [UNKNOWN][IEA] protein processing [UNKNOWN] positive regulation of coagulation [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] endopeptidase activity [UNKNOWN][IEA] peptidase activity [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTFMASDSE EEVCDERTSL MSAESPTSRS CQDSRPGPED GENTAQWRSQ ENEDDCEEDP  60
   61 DHYACSGVPG RPSGLEEELT LKYGAKHVIM LFVPVTLCMI VVVATIKSVR FYTEKNGQLI 120
  121 YTPFTEDTPS VGQRLLNSVL NTLIMISVIV VMTIFLVVLY KYRCYKFIHG WLIMSSLMLL 180
  181 FLFTYIYLGE VFKTYNVAMD YPTLFLAVWN FGAVGMVCIH WKGPLVLQQA YLIVISALMA 240
  241 LVFIKYLPEW SAWVILGAIS VYDLVAVLCP KGPLRMLVET AQERNEPIFP ALIYSSAMVW 300
  301 TVGMAKLDPS SQGALQLPYD PEMEEDSYDS FGEPSYPEAF EAPQPGYPGE EPEEEEERGV 360
  361 KLGLGDFIFY SVLVGKAAAT GNGDWSTTLA CFIAILIGLC LTLLLLAVFK KALPALPISI 420
  421 TFGLIFYFST DNLVRPFMDT LASHQLYI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PSN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: