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The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. The pattern specification process by which an axis or axes is subdivided in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. The process by which the neural tube is regionalized in the dorsoventral axis. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube. The regionalization process by which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.

View Gene Ontology (GO) Term


Name: dorsal/ventral neural tube patterning
Acc: GO:0021904
Aspect: Biological Process
Desc: The process by which the neural tube is regionalized in the dorsoventral axis.
  • dorsal-ventral neural tube patterning
  • dorsoventral neural tube patterning
Proteins in PDR annotated with:
   This term: 24 [Search]
   Term or descendants: 25 [Search]


GO:0021904 - dorsal/ventral neural tube patterning (interactive image map)

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