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A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. The process whereby a signal causes activation of T cell receptor signaling. Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response. Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. The signaling process whereby T cell signal transduction is brought to an end rather than being reversibly modulated. Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell receptor signaling pathway
Acc: GO:0050852
Aspect: Biological Process
Desc: A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms:
  • T-cell receptor signaling pathway
  • TCR signaling pathway
  • T-lymphocyte receptor signaling pathway
  • T-cell receptor signalling pathway
  • T-lymphocyte receptor signalling pathway
  • T lymphocyte receptor signalling pathway
  • T lymphocyte receptor signaling pathway
Proteins in PDR annotated with:
   This term: 40 [Search]
   Term or descendants: 61 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050852 - T cell receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle