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Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the Notch signaling pathway. The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell resulting in the modulation of the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. Any process that modulates the frequency, rate or extent of the Notch signaling pathway.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: Notch signaling pathway
Acc: GO:0007219
Aspect: Biological Process
Desc: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell.
Synonyms:
  • N signaling pathway
  • Notch receptor signaling pathway
  • Notch signalling pathway
  • Notch-receptor signalling pathway
  • Notch-receptor signaling pathway
  • Notch receptor signalling pathway
  • GO:0030179
  • N signalling pathway
Proteins in PDR annotated with:
   This term: 169 [Search]
   Term or descendants: 251 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007219 - Notch signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle