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Protein Overview: YCG1

General Information:
Name(s) found: YCG1 / YDR325W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation and chromatin binding of the condensin complex; required for clustering of tRNA genes at the nucleolus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1035 amino acids

    Gene Ontology:
    Cellular Component: nuclear condensin complex [IGILink to PubMed article][ISSLink to PubMed article]
    Biological Process: meiotic chromosome condensation [IMPLink to PubMed article]
    mitotic chromosome condensation [IGILink to PubMed article][IMPLink to PubMed article][TASLink to PubMed article]
    mitotic sister chromatid segregation [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDPDGIDIN TKIFNSVAEV FQKAQGSYAG HRKHIAVLKK IQSKAVEQGY EDAFNFWFDK  60
   61 LVTKILPLKK NEIIGDRIVK LVAAFIASLE RELILAKKQN YKLTNDEEGI FSRFVDQFIR 120
  121 HVLRGVESPD KNVRFRVLQL LAVIMDNIGE IDESLFNLLI LSLNKRIYDR EPTVRIQAVF 180
  181 CLTKFQDEEQ TEHLTELSDN EENFEATRTL VASIQNDPSA EVRRAAMLNL INDNNTRPYI 240
  241 LERARDVNIV NRRLVYSRIL KSMGRKCFDD IEPHIFDQLI EWGLEDRELS VRNACKRLIA 300
  301 HDWLNALDGD LIELLEKLDV SRSSVCVKAI EALFQSRPDI LSKIKFPESI WKDFTVEIAF 360
  361 LFRAIYLYCL DNNITEMLEE NFPEASKLSE HLNHYILLRY HHNDISNDSQ SHFDYNTLEF 420
  421 IIEQLSIAAE RYDYSDEVGR RSMLTVVRNM LALTTLSEPL IKIGIRVMKS LSINEKDFVT 480
  481 MAIEIINDIR DDDIEKQEQE EKIKSKKINR RNETSVDEED ENGTHNDEVN EDEEDDNISS 540
  541 FHSAVENLVQ GNGNVSESDI INNLPPEKEA SSATIVLCLT RSSYMLELVN TPLTENILIA 600
  601 SLMDTLITPA VRNTAPNIRE LGVKNLGLCC LLDVKLAIDN MYILGMCVSK GNASLKYIAL 660
  661 QVIVDIFSVH GNTVVDGEGK VDSISLHKIF YKVLKNNGLP ECQVIAAEGL CKLFLADVFT 720
  721 DDDLFETLVL SYFSPINSSN EALVQAFAFC IPVYCFSHPA HQQRMSRTAA DILLRLCVLW 780
  781 DDLQSSVIPE VDREAMLKPN IIFQQLLFWT DPRNLVNQTG STKKDTVQLT FLIDVLKIYA 840
  841 QIEKKEIKKM IITNINAIFL SSEQDYSTLK ELLEYSDDIA ENDNLDNVSK NALDKLRNNL 900
  901 NSLIEEINER SETQTKDENN TANDQYSSIL GNSFNKSSND TIEHAADITD GNNTELTKTT 960
  961 VNISAVDNTT EQSNSRKRTR SEAEQIDTSK NLENMSIQDT STVAKNVSFV LPDEKSDAMS1020
 1021 IDEEDKDSES FSEVC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BRN1 HIS2 SMC2 SMC4 YCG1 YCS4
    View Details Qiu et al. (2008) SMC2 SMC4 YCG1 YCS4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YCG1 Huh WK, et al. (2003)
    View Data YCG1 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] PSI-BLAST 22.69897 Adaptin beta subunit N-terminal fragment
    2 View Details [70..716] PSI-BLAST 23.154902 Constant regulatory domain of protein phosphatase 2a, pr65alpha
    3 View Details [717..793] deduced N/A No confident structure predictions are available.
    4 View Details [794..1035] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle