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Protein Overview: PHO91

General Information:
Name(s) found: PHO91 / YNR013C [SGD]
Description(s) found:
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  • gi|732208|sp|P27514.2|YN86_YEAST RecName: Full=Uncharacterized transporter YNR013C [NCBI NR]
  • gi|6324340|ref|NP_014410.1| Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous g [NCBI NR]
  • pir||S45135 probable membrane protein YNR013c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|496729|emb|CAA54581.1| N2052 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1302492|emb|CAA96290.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Uncharacterized transporter YNR013C OS=Saccharomyces cerevisiae GN=YNR013C PE=1 SV=2 [Swiss-Prot]
  • PHO91 Low-affinity phosphate transporter [mips]
  • Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth [SGD]
  • (P27514) Hypothetical 99.5 kDa protein in URK1-SMM1 intergenic region [4932.FASTACCERV.txt]
  • Chr XIV from 651709-649025, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XIV from 649025-651709, reverse complement [yeastorf3.fasta]
  • PHO91, Chr XIV from 649025-651709, reverse complement [yeast_orfs2]
  • PHO91 SGDID:S0005296, Chr XIV from 651711-649027, reverse complement, Verified ORF [yeastflysequest.fasta]
  • PHO91 SGDID:S0005296, Chr XIV from 651712-649028, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth [Saccharomyces cerevisiae]gi|1302492|emb|CAA96 [nrdb_11152004_Chlamydomonas]
  • PHO91 SGDID:S000005296, Chr XIV from 651714-649030, reverse complement, Verified ORF, "Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; ov [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651714-649030, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • N2052 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth; Pho91p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Uncharacterized transporter YNR013C [nr-271106-contam.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651715-649031, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651714-649030, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [yeast-bovrabprots.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651714-649030, reverse complement, Verified ORF, "Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [yeast-contam_custom.fasta]
  • [chemostatdb.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651715-649031, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [SGDyeast.20101221.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651712-649028, Genome Release 64-1-1, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [yeast-030211-contam.fasta]
  • PHO91 SGDID:S000005296, Chr XIV from 651712-649028, Genome Release 64-2-1, reverse complement, Verified ORF, "Low-affinity vacuolar phosphate transporter; exports phosphate from the vacuolar lumen to the cytosol; regulates phosphate and polyphosphate metabolism; acts upstream of Pho81p in regulation of the PHO pathway; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [20141208_orf_trans.fasta]
  • YNR013C SGDID:S000005296, Chr XIV from 651712-649028, Genome Release 64-1-1, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 894 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    Biological Process: phosphate transport [IGILink to PubMed article]
    Molecular Function: phosphate transmembrane transporter activity [IGILink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSHSLQFN SVPEWSTKYL AYSQLKKLIY SLQKDKLYSN NKHHVVEPHD ANDENLPLLA  60
   61 DASPDDQFYI SKFVAALNQE LKKIDKFYIS QETGLIANYN ELKDDVMELE NTNKATQLFN 120
  121 QQQQHQLQSV ARNRKSKSQQ RQRRFSSVSS TDSNPSLTDM SIDSAPVIHT QVSNTTNNGN 180
  181 SMQNLASASV SLSNSNPVYL SPFTQHRLSL KKRLISIYTQ LSELKDFIEL NQTGFSKICK 240
  241 KFDKSLNTNL KQNYLNYIKF HSHVFNPATI NRIQHHITET ILTYASLNKG TRRPSNTFNL 300
  301 DADRINNDEN SSGNEEDEDG NRQEVLDFQD AERELSSHLR DHVVWERNTV WKDMMNLERK 360
  361 YQSAKTDNKK FSKLSSSQLR PNANITESMA MSSGGAGIIA PSTDSLTFRE LMHLPPKQWL 420
  421 QFIMGQTSLL KFLLITSCFI ALLTFNLTPF TQDSLQKNCF AILIYASLLW ATETIPLFVT 480
  481 SLMIPLLIVV FPVIKDPITS QPMSPRDSSQ FILSTMWSSV IMLLLGGFTL AAALSKYNIA 540
  541 KVLSTHILAS AGTNPHFILL TNMFVALFVS MWVSNVAAPV LCYSIVQPLL RTLPRNCSYA 600
  601 KALILGIALA SNIGGMSSPI ASPQNIFSIG IMDPSPSWAE WFMIALPVCF ICVMAIWVLL 660
  661 IITFPPEPNV KILQLHPSRD PFTLKQWFVT LVCIITIVLW CLSNQISGIF GEMGIISIIP 720
  721 IVVFFGTGLL TSDDFNNFMW TIVVLAMGGT TLGKAVSSSG LLSTMAQLIK AQVEHEPIFI 780
  781 IVLIFGLVIL VMATFVSHTV AAMIIVPLMS EIGSNLPSGD HSRLLIVIAA LLCSSAMGLP 840
  841 TSGFPNVTAI SMIDEVGDRY LTVGTFITRG VPASLLSYAA IVTVGYGILK VMGF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARC1 ATG14 CAT8 CCC2 HEK2 IRC20 MCA1 MES1 MGA2 NCS2 NHA1 PET127 PHO89 PHO91 YKL050C YLR363W-A
    View Details Qiu et al. (2008) PHO90 PHO91

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 sample: hx3 Hao Xu, et al. (2010)
    View Run VAM3 sample: hx4 Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)
    View Run VAM3 hx21: both fusion and trans-SNARE complex formation take place. Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run VAM3 hx23: mixture in detergent (control) Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PHO91 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..312] Pfam 71.769551 SPX domain No confident structure predictions are available.
    2 View Details [313..402] deduced N/A No confident structure predictions are available.
    3 View Details [403..894] Pfam 7.638272 Sodium:sulfate symporter transmembrane region No confident structure predictions are available.
    4 View Details [594..682] deduced N/A No confident structure predictions are available.
    5 View Details [683..894] MSA 14.275995 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle