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Protein Overview: YKL050C

General Information:
Name(s) found: YKL050C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein of unknown function; the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex and YKL050W transcription is regulated by Azf1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 922 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLISALQTT DVESVQTSPE QITERKAVRV STLQESLHSS EMHRAAPETP RSISNSVHKL  60
   61 KTIYSTYQQS GQPLSKEAIF RAKQKYGILN TPANYKTLGL GDSKSESVDL AARLASKRTK 120
  121 VSPDDCVETA IEQKARGEAF KVTFSKIPLT PPEDVPITVN LGLKGRRDFL TRLAAQKALA 180
  181 FSPSLDNSMK GTSDSSSVKK KRFSGAPIGN EFDANLVNPQ HPAGFKSLDL SKVLDGAERR 240
  241 AISRVNDRLY PQKVNFKNGL QSSDQSGVSK ANKEVFKKGT LEKLEHSAEQ FLESHAGNER 300
  301 QRLSDQQYMC AKGAADAVKD LDPKTLEDPD FAAREAQKKL YIKQVASPVV LNEAQKLANR 360
  361 KLQDIDSRDT YMLLFGNQAY NKLAVNIALQ HYSVKQEEKK KIYLGGGLWM TPEEVNAVAK 420
  421 KLISPVVNEI DERASRQRDV DKDIERRSRV LDQEYEDGNS MERAKEQNDG QLLLAMASKQ 480
  481 QQEKEAKKAE EGQRYDQFVQ KMNIKLQQKE KELENARENR ENLRNELQER LSKNLSGEND 540
  541 ELNDWNDACE RDLKNSSIEH YYAVRSHFDN LGNSERGYDE LLEERSKIQV EIERLVASIA 600
  601 EHKTAIHGFG ETADAGGAIP AVQKQKIPTR KDLLDATVND PLVISAEMAK EEAEMATEEC 660
  661 MLKELQVDEM IIIRNIMLRE CEKKLEEEKE TAKRSRRGTE ESKNNSNFSR DVIMSTPDNN 720
  721 EKVTPIGKSA SPKDVVKSRF LSTYNTGKDI DSSASARSIT GVSGVLDDGP KTPTSNKENE 780
  781 LIDDEVKSYK VHQAVDGTGE DSIANKRDKS SRPAANSGGS ITIEQFLFNK NADKQGLSKT 840
  841 ESVTMKREPV VDQMDSKKGH DFTHCNDNGR RSFSGFSQGS IENDYSNEVT DDQDDQEGSE 900
  901 IRVRDSNDSN TSPKESFFKE VI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARC1 ATG14 CAT8 CCC2 HEK2 IRC20 MCA1 MES1 MGA2 NCS2 NHA1 PET127 PHO89 PHO91 YKL050C YLR363W-A

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A No confident structure predictions are available.
    2 View Details [73..395] PSI-BLAST 13.154902 Heavy meromyosin subfragment
    3 View Details [396..619] PSI-BLAST 8.045757 Tropomyosin
    4 View Details [620..868] MSA 4.011996 View MSA. No confident structure predictions are available.
    5 View Details [869..922] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle