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Protein Overview: RRN3

General Information:
Name(s) found: RRN3 / YKL125W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 627 amino acids

    Gene Ontology:
    Cellular Component: RNA polymerase I transcription factor complex [TASLink to PubMed article]
    Biological Process: transcription from RNA polymerase I promoter [TASLink to PubMed article]
    Molecular Function: RNA polymerase I transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMAFENTSKR PPQDFVAPID QKKRKVQFSD STGLVTLQPE EIKDEVFSAA MYSRFVKSAL  60
   61 DDLDKNDSTQ IGIIANQVAL PSKNPERIND KNLNILLDIL SSNINRIESS RGTFLIQSII 120
  121 NFEKWWELPP HTLSKYIYFI KILCSSIPKW WQDVSMILVS CFILPIKQTV CHHDMLKYFL 180
  181 RMIPSSMGFI DTYLAKFFPN KNDTRRKLVN YTSNLLKLRG YCSELGFQIW SLLIEKIISI 240
  241 DVELQNELDE LDDDVDDDDL EEVDLEDDDD LDDDSGDDDD ENCGNSNEEL RSGAADGSQS 300
  301 DSEDMDIIEG MDGTEEYNVE LTQGIKELST KLDSILTLVS THVEEQVTPE SLESGEGVGV 360
  361 FNTLTTLFKT HVLPTYYTRS IQYIMFHVSQ QQLELMDSFL VTLIDISFAV NEAAEKKIKS 420
  421 LQYLGSYIAR AKKLSRTQII FVASYLTSWL NRYVIEREEE VDQRGGMERF KHFYAAFQAL 480
  481 CYIFCFRHNI FRDTDGNWEC ELDKFFQRMV ISKFNPLKFC NENVMLMFAR IAQQESVAYC 540
  541 FSIIENNNNE RLRGIIGKAD SDKKENSAQA NTTSSSWSLA TRQQFIDLQS YFPYDPLFLK 600
  601 NYKILMKEYY IEWSEASGEY ESDGSDD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) RPS25A RRN3
    View Details Gavin AC, et al. (2002) ACT1 ERG13 LYS12 NCS2 RRN3 SAM1
    View Details Qiu et al. (2008) RRN10 RRN11 RRN3 RRN5 RRN6 RRN7 RRN9 SPT15 UAF30

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #21 Asynchronous Prep2-IMAC Phosphopeptide enrichment A1 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RRN3 Huh WK, et al. (2003)
    View Data RRN3 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..272] ab initio 8.3 No description for 1b3uA was found.
    2 View Details [273..504] deduced N/A No confident structure predictions are available.
    3 View Details [505..627] MSA 1.010974 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle